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Results: 1 to 20 of 98

1.

Disease-modifying effect of strontium ranelate in a subset of patients from the Phase III knee osteoarthritis study SEKOIA using quantitative MRI: reduction in bone marrow lesions protects against cartilage loss.

Pelletier JP, Roubille C, Raynauld JP, Abram F, Dorais M, Delorme P, Martel-Pelletier J.

Ann Rheum Dis. 2013 Dec 2. doi: 10.1136/annrheumdis-2013-203989. [Epub ahead of print]

PMID:
24297379
[PubMed - as supplied by publisher]
2.

Strontium ranelate reduces the progression of experimental dog osteoarthritis by inhibiting the expression of key proteases in cartilage and of IL-1β in the synovium.

Pelletier JP, Kapoor M, Fahmi H, Lajeunesse D, Blesius A, Maillet J, Martel-Pelletier J.

Ann Rheum Dis. 2013 Feb;72(2):250-7. doi: 10.1136/annrheumdis-2012-201710. Epub 2012 Oct 13.

PMID:
23065732
[PubMed - indexed for MEDLINE]
3.

Chondroitin sulphate reduces both cartilage volume loss and bone marrow lesions in knee osteoarthritis patients starting as early as 6 months after initiation of therapy: a randomised, double-blind, placebo-controlled pilot study using MRI.

Wildi LM, Raynauld JP, Martel-Pelletier J, Beaulieu A, Bessette L, Morin F, Abram F, Dorais M, Pelletier JP.

Ann Rheum Dis. 2011 Jun;70(6):982-9. doi: 10.1136/ard.2010.140848. Epub 2011 Mar 1.

PMID:
21367761
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Efficacy and safety of strontium ranelate in the treatment of knee osteoarthritis: results of a double-blind, randomised placebo-controlled trial.

Reginster JY, Badurski J, Bellamy N, Bensen W, Chapurlat R, Chevalier X, Christiansen C, Genant H, Navarro F, Nasonov E, Sambrook PN, Spector TD, Cooper C.

Ann Rheum Dis. 2013 Feb;72(2):179-86. doi: 10.1136/annrheumdis-2012-202231. Epub 2012 Nov 1.

PMID:
23117245
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Strontium ranelate in the treatment of knee osteoarthritis: new insights and emerging clinical evidence.

Reginster JY, Beaudart C, Neuprez A, Bruyère O.

Ther Adv Musculoskelet Dis. 2013 Oct;5(5):268-76. doi: 10.1177/1759720X13500862.

PMID:
24101948
[PubMed]
Free PMC Article
6.

Increase in bone marrow lesions associated with cartilage loss: a longitudinal magnetic resonance imaging study of knee osteoarthritis.

Hunter DJ, Zhang Y, Niu J, Goggins J, Amin S, LaValley MP, Guermazi A, Genant H, Gale D, Felson DT.

Arthritis Rheum. 2006 May;54(5):1529-35.

PMID:
16646037
[PubMed - indexed for MEDLINE]
Free Article
7.

Protective effects of licofelone, a 5-lipoxygenase and cyclo-oxygenase inhibitor, versus naproxen on cartilage loss in knee osteoarthritis: a first multicentre clinical trial using quantitative MRI.

Raynauld JP, Martel-Pelletier J, Bias P, Laufer S, Haraoui B, Choquette D, Beaulieu AD, Abram F, Dorais M, Vignon E, Pelletier JP; Canadian Licofelone Study Group.

Ann Rheum Dis. 2009 Jun;68(6):938-47. doi: 10.1136/ard.2008.088732. Epub 2008 Jul 23.

PMID:
18653484
[PubMed - indexed for MEDLINE]
8.

Quantitative bone marrow lesion size in osteoarthritic knees correlates with cartilage damage and predicts longitudinal cartilage loss.

Driban JB, Lo GH, Lee JY, Ward RJ, Miller E, Pang J, Price LL, McAlindon TE.

BMC Musculoskelet Disord. 2011 Sep 30;12:217. doi: 10.1186/1471-2474-12-217.

PMID:
21961433
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Bone marrow lesions predict site-specific cartilage defect development and volume loss: a prospective study in older adults.

Dore D, Martens A, Quinn S, Ding C, Winzenberg T, Zhai G, Pelletier JP, Martel-Pelletier J, Abram F, Cicuttini F, Jones G.

Arthritis Res Ther. 2010;12(6):R222. doi: 10.1186/ar3209. Epub 2010 Dec 29.

PMID:
21190554
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Risk factors associated with the loss of cartilage volume on weight-bearing areas in knee osteoarthritis patients assessed by quantitative magnetic resonance imaging: a longitudinal study.

Pelletier JP, Raynauld JP, Berthiaume MJ, Abram F, Choquette D, Haraoui B, Beary JF, Cline GA, Meyer JM, Martel-Pelletier J.

Arthritis Res Ther. 2007;9(4):R74.

PMID:
17672891
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Clinically meaningful effect of strontium ranelate on symptoms in knee osteoarthritis: a responder analysis.

Bruyère O, Reginster JY, Bellamy N, Chapurlat R, Richette P, Cooper C; SEKOIA investigators.

Rheumatology (Oxford). 2014 Aug;53(8):1457-64. doi: 10.1093/rheumatology/keu018. Epub 2014 Mar 25.

PMID:
24667161
[PubMed - in process]
12.

Analysis of the precision and sensitivity to change of different approaches to assess cartilage loss by quantitative MRI in a longitudinal multicentre clinical trial in patients with knee osteoarthritis.

Raynauld JP, Martel-Pelletier J, Abram F, Dorais M, Haraoui B, Choquette D, Bias P, Emmert KH, Laufer S, Pelletier JP.

Arthritis Res Ther. 2008;10(6):R129. doi: 10.1186/ar2543. Epub 2008 Nov 5.

PMID:
18986534
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Long term evaluation of disease progression through the quantitative magnetic resonance imaging of symptomatic knee osteoarthritis patients: correlation with clinical symptoms and radiographic changes.

Raynauld JP, Martel-Pelletier J, Berthiaume MJ, Beaudoin G, Choquette D, Haraoui B, Tannenbaum H, Meyer JM, Beary JF, Cline GA, Pelletier JP.

Arthritis Res Ther. 2006;8(1):R21. Epub 2005 Dec 30.

PMID:
16507119
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

A study of the prevalence and associations of subchondral bone marrow lesions in the knees of healthy, middle-aged women.

Guymer E, Baranyay F, Wluka AE, Hanna F, Bell RJ, Davis SR, Wang Y, Cicuttini FM.

Osteoarthritis Cartilage. 2007 Dec;15(12):1437-42. Epub 2007 Jun 7.

PMID:
17560134
[PubMed - indexed for MEDLINE]
Free Article
15.

Changes in bone marrow lesions in response to weight-loss in obese knee osteoarthritis patients: a prospective cohort study.

Gudbergsen H, Boesen M, Christensen R, Bartels EM, Henriksen M, Danneskiold-Samsøe B, Bliddal H.

BMC Musculoskelet Disord. 2013 Mar 22;14:106. doi: 10.1186/1471-2474-14-106.

PMID:
23522337
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Risedronate decreases biochemical markers of cartilage degradation but does not decrease symptoms or slow radiographic progression in patients with medial compartment osteoarthritis of the knee: results of the two-year multinational knee osteoarthritis structural arthritis study.

Bingham CO 3rd, Buckland-Wright JC, Garnero P, Cohen SB, Dougados M, Adami S, Clauw DJ, Spector TD, Pelletier JP, Raynauld JP, Strand V, Simon LS, Meyer JM, Cline GA, Beary JF.

Arthritis Rheum. 2006 Nov;54(11):3494-507.

PMID:
17075851
[PubMed - indexed for MEDLINE]
Free Article
17.

Central bone marrow lesions in symptomatic knee osteoarthritis and their relationship to anterior cruciate ligament tears and cartilage loss.

Hernández-Molina G, Guermazi A, Niu J, Gale D, Goggins J, Amin S, Felson DT.

Arthritis Rheum. 2008 Jan;58(1):130-6. doi: 10.1002/art.23173.

PMID:
18163483
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Bone marrow lesions in knee osteoarthritis change in 6-12 weeks.

Felson DT, Parkes MJ, Marjanovic EJ, Callaghan M, Gait A, Cootes T, Lunt M, Oldham J, Hutchinson CE.

Osteoarthritis Cartilage. 2012 Dec;20(12):1514-8. doi: 10.1016/j.joca.2012.08.020. Epub 2012 Sep 1.

PMID:
22944524
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Correlation between bone lesion changes and cartilage volume loss in patients with osteoarthritis of the knee as assessed by quantitative magnetic resonance imaging over a 24-month period.

Raynauld JP, Martel-Pelletier J, Berthiaume MJ, Abram F, Choquette D, Haraoui B, Beary JF, Cline GA, Meyer JM, Pelletier JP.

Ann Rheum Dis. 2008 May;67(5):683-8. Epub 2007 Aug 29.

PMID:
17728333
[PubMed - indexed for MEDLINE]
20.

Change in MRI-detected subchondral bone marrow lesions is associated with cartilage loss: the MOST Study. A longitudinal multicentre study of knee osteoarthritis.

Roemer FW, Guermazi A, Javaid MK, Lynch JA, Niu J, Zhang Y, Felson DT, Lewis CE, Torner J, Nevitt MC; MOST Study investigators.

Ann Rheum Dis. 2009 Sep;68(9):1461-5. doi: 10.1136/ard.2008.096834. Epub 2008 Oct 1.

PMID:
18829615
[PubMed - indexed for MEDLINE]
Free PMC Article

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