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Results: 1 to 20 of 165

1.

Serine hydrolase inhibitors block necrotic cell death by preventing calcium overload of the mitochondria and permeability transition pore formation.

Yun B, Lee H, Ghosh M, Cravatt BF, Hsu KL, Bonventre JV, Ewing H, Gelb MH, Leslie CC.

J Biol Chem. 2014 Jan 17;289(3):1491-504. doi: 10.1074/jbc.M113.497651. Epub 2013 Dec 2.

PMID:
24297180
[PubMed - indexed for MEDLINE]
2.

CaMKII determines mitochondrial stress responses in heart.

Joiner ML, Koval OM, Li J, He BJ, Allamargot C, Gao Z, Luczak ED, Hall DD, Fink BD, Chen B, Yang J, Moore SA, Scholz TD, Strack S, Mohler PJ, Sivitz WI, Song LS, Anderson ME.

Nature. 2012 Nov 8;491(7423):269-73. doi: 10.1038/nature11444. Epub 2012 Oct 10.

PMID:
23051746
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Genetic ablation of calcium-independent phospholipase A(2)γ (iPLA(2)γ) attenuates calcium-induced opening of the mitochondrial permeability transition pore and resultant cytochrome c release.

Moon SH, Jenkins CM, Kiebish MA, Sims HF, Mancuso DJ, Gross RW.

J Biol Chem. 2012 Aug 24;287(35):29837-50. doi: 10.1074/jbc.M112.373654. Epub 2012 Jul 9.

PMID:
22778252
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Hydrogen peroxide-induced arachidonic acid release in L929 cells; roles of Src, protein kinase C and cytosolic phospholipase A2alpha.

Taniguchi T, Shimizu M, Nakamura H, Hirabayashi T, Fujino H, Murayama T.

Eur J Pharmacol. 2006 Sep 28;546(1-3):1-10. Epub 2006 Jul 5.

PMID:
16914136
[PubMed - indexed for MEDLINE]
5.

Local control of mitochondrial membrane potential, permeability transition pore and reactive oxygen species by calcium and calmodulin in rat ventricular myocytes.

Odagiri K, Katoh H, Kawashima H, Tanaka T, Ohtani H, Saotome M, Urushida T, Satoh H, Hayashi H.

J Mol Cell Cardiol. 2009 Jun;46(6):989-97. doi: 10.1016/j.yjmcc.2008.12.022. Epub 2009 Jan 20.

PMID:
19318235
[PubMed - indexed for MEDLINE]
6.

Opening of mitochondrial permeability transition pore induces hypercontracture in Ca2+ overloaded cardiac myocytes.

Ruiz-Meana M, Abellán A, Miró-Casas E, Garcia-Dorado D.

Basic Res Cardiol. 2007 Nov;102(6):542-52. Epub 2007 Sep 24.

PMID:
17891523
[PubMed - indexed for MEDLINE]
7.

Calcium-induced cardiac mitochondrial dysfunction is predominantly mediated by cyclosporine A-dependent mitochondrial permeability transition pore.

Yarana C, Sripetchwandee J, Sanit J, Chattipakorn S, Chattipakorn N.

Arch Med Res. 2012 Jul;43(5):333-8. doi: 10.1016/j.arcmed.2012.06.010. Epub 2012 Jul 21.

PMID:
22824212
[PubMed - indexed for MEDLINE]
8.

Inhibition of alpha-ketoglutarate dehydrogenase complex promotes cytochrome c release from mitochondria, caspase-3 activation, and necrotic cell death.

Huang HM, Ou HC, Xu H, Chen HL, Fowler C, Gibson GE.

J Neurosci Res. 2003 Oct 15;74(2):309-17.

PMID:
14515360
[PubMed - indexed for MEDLINE]
9.

Interplay between Ca2+ cycling and mitochondrial permeability transition pores promotes reperfusion-induced injury of cardiac myocytes.

Abdallah Y, Kasseckert SA, Iraqi W, Said M, Shahzad T, Erdogan A, Neuhof C, Gündüz D, Schlüter KD, Tillmanns H, Piper HM, Reusch HP, Ladilov Y.

J Cell Mol Med. 2011 Nov;15(11):2478-85. doi: 10.1111/j.1582-4934.2010.01249.x.

PMID:
21199327
[PubMed - indexed for MEDLINE]
10.

Ser515 phosphorylation-independent regulation of cytosolic phospholipase A2alpha (cPLA2alpha) by calmodulin-dependent protein kinase: possible interaction with catalytic domain A of cPLA2alpha.

Shimizu M, Nakamura H, Hirabayashi T, Suganami A, Tamura Y, Murayama T.

Cell Signal. 2008 May;20(5):815-24. doi: 10.1016/j.cellsig.2007.12.016. Epub 2008 Jan 4.

PMID:
18280113
[PubMed - indexed for MEDLINE]
11.

Mechanism of cyclosporin-induced inhibition of intracellular collagen degradation.

Arora PD, Silvestri L, Ganss B, Sodek J, McCulloch CA.

J Biol Chem. 2001 Apr 27;276(17):14100-9. Epub 2001 Jan 22.

PMID:
11278659
[PubMed - indexed for MEDLINE]
Free Article
12.

Cysteine 203 of cyclophilin D is critical for cyclophilin D activation of the mitochondrial permeability transition pore.

Nguyen TT, Stevens MV, Kohr M, Steenbergen C, Sack MN, Murphy E.

J Biol Chem. 2011 Nov 18;286(46):40184-92. doi: 10.1074/jbc.M111.243469. Epub 2011 Sep 19.

PMID:
21930693
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Bnip3-mediated mitochondrial autophagy is independent of the mitochondrial permeability transition pore.

Quinsay MN, Thomas RL, Lee Y, Gustafsson AB.

Autophagy. 2010 Oct;6(7):855-62.

PMID:
20668412
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Not all mitochondrial carrier proteins support permeability transition pore formation: no involvement of uncoupling protein 1.

Crichton PG, Parker N, Vidal-Puig AJ, Brand MD.

Biosci Rep. 2009 Dec 15;30(3):187-92. doi: 10.1042/BSR20090063.

PMID:
19622065
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Oxidant-induced inhibition of the plasma membrane Ca2+-ATPase in pancreatic acinar cells: role of the mitochondria.

Baggaley EM, Elliott AC, Bruce JI.

Am J Physiol Cell Physiol. 2008 Nov;295(5):C1247-60. doi: 10.1152/ajpcell.00083.2008. Epub 2008 Sep 11.

PMID:
18787078
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Palmitic acid opens a novel cyclosporin A-insensitive pore in the inner mitochondrial membrane.

Sultan A, Sokolove PM.

Arch Biochem Biophys. 2001 Feb 1;386(1):37-51.

PMID:
11360999
[PubMed - indexed for MEDLINE]
17.

Calcineurin-independent inhibition of mitochondrial Ca2+ uptake by cyclosporin A.

Montero M, Lobatón CD, Gutierrez-Fernández S, Moreno A, Alvarez J.

Br J Pharmacol. 2004 Jan;141(2):263-8. Epub 2003 Dec 22.

PMID:
14691054
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Measurements of threshold of mitochondrial permeability transition pore opening in intact and permeabilized cells by flash photolysis of caged calcium.

Abramov AY, Duchen MR.

Methods Mol Biol. 2011;793:299-309. doi: 10.1007/978-1-61779-328-8_19.

PMID:
21913108
[PubMed - indexed for MEDLINE]
19.

Cyclophilin D gene ablation protects mice from ischemic renal injury.

Devalaraja-Narashimha K, Diener AM, Padanilam BJ.

Am J Physiol Renal Physiol. 2009 Sep;297(3):F749-59. doi: 10.1152/ajprenal.00239.2009. Epub 2009 Jun 24.

PMID:
19553348
[PubMed - indexed for MEDLINE]
Free Article

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