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Results: 1 to 20 of 97

Similar articles for PubMed (Select 24289083)

1.

Blockage of hERG current and the disruption of trafficking as induced by roxithromycin.

Han SN, Yang SH, Zhang Y, Duan YY, Sun XY, Chen Q, Fan TL, Ye ZK, Huang CZ, Hu XJ, Zhang Z, Zhang LR.

Can J Physiol Pharmacol. 2013 Dec;91(12):1112-8. doi: 10.1139/cjpp-2012-0456. Epub 2013 Sep 3.

PMID:
24289083
2.

The protease inhibitor atazanavir blocks hERG K(+) channels expressed in HEK293 cells and obstructs hERG protein transport to cell membrane.

Han SN, Sun XY, Zhang Z, Zhang LR.

Acta Pharmacol Sin. 2015 Apr;36(4):454-62. doi: 10.1038/aps.2014.165. Epub 2015 Mar 23.

3.

Up-regulation of miR-21 and miR-23a Contributes to As2 O3 -induced hERG Channel Deficiency.

Zhao X, Shi YQ, Yan CC, Feng PF, Wang X, Zhang R, Zhang X, Li BX.

Basic Clin Pharmacol Toxicol. 2015 Jun;116(6):516-23. doi: 10.1111/bcpt.12348. Epub 2014 Dec 17.

PMID:
25395240
4.

The variant hERG/R148W associated with LQTS is a mutation that reduces current density on co-expression with the WT.

Mechakra A, Vincent Y, Chevalier P, Millat G, Ficker E, Jastrzebski M, Poulin H, Pouliot V, Chahine M, Christé G.

Gene. 2014 Feb 25;536(2):348-56. doi: 10.1016/j.gene.2013.11.072. Epub 2013 Dec 12.

PMID:
24334129
5.

Mechanism of hERG channel block by the psychoactive indole alkaloid ibogaine.

Thurner P, Stary-Weinzinger A, Gafar H, Gawali VS, Kudlacek O, Zezula J, Hilber K, Boehm S, Sandtner W, Koenig X.

J Pharmacol Exp Ther. 2014 Feb;348(2):346-58. doi: 10.1124/jpet.113.209643. Epub 2013 Dec 4.

6.

Effect of azelastine on cardiac repolarization of guinea-pig cardiomyocytes, hERG K⁺ channel, and human L-type and T-type Ca²⁺ channel.

Park MH, Lee SH, Chu DH, Won KH, Choi BH, Choe H, Jo SH.

J Pharmacol Sci. 2013 Sep 20;123(1):67-77. Epub 2013 Sep 3.

7.

Hsp90 prevents interaction between CHIP and HERG proteins to facilitate maturation of wild-type and mutant HERG proteins.

Iwai C, Li P, Kurata Y, Hoshikawa Y, Morikawa K, Maharani N, Higaki K, Sasano T, Notsu T, Ishido Y, Miake J, Yamamoto Y, Shirayoshi Y, Ninomiya H, Nakai A, Murata S, Yoshida A, Yamamoto K, Hiraoka M, Hisatome I.

Cardiovasc Res. 2013 Dec 1;100(3):520-8. doi: 10.1093/cvr/cvt200. Epub 2013 Aug 20.

8.

Blockade of the human ether-a-go-go-related gene potassium channel by ketamine.

Zhang P, Xing J, Luo A, Feng J, Liu Z, Gao C, Ma J.

J Pharm Pharmacol. 2013 Sep;65(9):1321-8. doi: 10.1111/jphp.12095. Epub 2013 Jul 10.

PMID:
23927470
9.

Block of hERG K+ channel and prolongation of action potential duration by fluphenazine at submicromolar concentration.

Hong HK, Lee BH, Park MH, Lee SH, Chu D, Kim WJ, Choe H, Hee Choi B, Jo SH.

Eur J Pharmacol. 2013 Feb 28;702(1-3):165-73. doi: 10.1016/j.ejphar.2013.01.039. Epub 2013 Feb 6.

PMID:
23395964
10.

Blocking of the human ether-à-go-go-related gene channel by imatinib mesylate.

Dong Q, Fu XX, Du LL, Zhao N, Xia CK, Yu KW, Cheng LX, Du YM.

Biol Pharm Bull. 2013;36(2):268-75. Epub 2012 Nov 30.

11.

L539 fs/47, a truncated mutation of human ether-a-go-go-related gene (hERG), decreases hERG ion channel currents in HEK 293 cells.

Zhang A, Sun C, Zhang L, Lv Y, Xue X, Li G, Cui C, Yan GX.

Clin Exp Pharmacol Physiol. 2013 Jan;40(1):28-36. doi: 10.1111/1440-1681.12028.

PMID:
23134353
12.

Mechanisms of zolpidem-induced long QT syndrome: acute inhibition of recombinant hERG K(+) channels and action potential prolongation in human cardiomyocytes derived from induced pluripotent stem cells.

Jehle J, Ficker E, Wan X, Deschenes I, Kisselbach J, Wiedmann F, Staudacher I, Schmidt C, Schweizer PA, Becker R, Katus HA, Thomas D.

Br J Pharmacol. 2013 Mar;168(5):1215-29. doi: 10.1111/bph.12002.

13.

Identification and functional characterization of the novel human ether-a-go-go-related gene (hERG) R744P mutant associated with hereditary long QT syndrome 2.

Aidery P, Kisselbach J, Gaspar H, Baldea I, Schweizer PA, Becker R, Katus HA, Thomas D.

Biochem Biophys Res Commun. 2012 Feb 24;418(4):830-5. doi: 10.1016/j.bbrc.2012.01.118. Epub 2012 Jan 30.

PMID:
22314138
14.

Molecular determinants of hERG potassium channel inhibition by disopyramide.

El Harchi A, Zhang YH, Hussein L, Dempsey CE, Hancox JC.

J Mol Cell Cardiol. 2012 Jan;52(1):185-95. doi: 10.1016/j.yjmcc.2011.09.021. Epub 2011 Sep 29.

PMID:
21989164
15.

Antidepressant-induced ubiquitination and degradation of the cardiac potassium channel hERG.

Dennis AT, Nassal D, Deschenes I, Thomas D, Ficker E.

J Biol Chem. 2011 Sep 30;286(39):34413-25. doi: 10.1074/jbc.M111.254367. Epub 2011 Aug 9.

16.

HIV Tat protein inhibits hERG K+ channels: a potential mechanism of HIV infection induced LQTs.

Bai YL, Liu HB, Sun B, Zhang Y, Li Q, Hu CW, Zhu JX, Gong DM, Teng X, Zhang Q, Yang BF, Dong DL.

J Mol Cell Cardiol. 2011 Nov;51(5):876-80. doi: 10.1016/j.yjmcc.2011.07.017. Epub 2011 Jul 28.

PMID:
21820442
17.

Progesterone impairs human ether-a-go-go-related gene (HERG) trafficking by disruption of intracellular cholesterol homeostasis.

Wu ZY, Yu DJ, Soong TW, Dawe GS, Bian JS.

J Biol Chem. 2011 Jun 24;286(25):22186-94. doi: 10.1074/jbc.M110.198853. Epub 2011 Apr 27.

18.

Trafficking-deficient hERG K⁺ channels linked to long QT syndrome are regulated by a microtubule-dependent quality control compartment in the ER.

Smith JL, McBride CM, Nataraj PS, Bartos DC, January CT, Delisle BP.

Am J Physiol Cell Physiol. 2011 Jul;301(1):C75-85. doi: 10.1152/ajpcell.00494.2010. Epub 2011 Apr 13.

19.

Trafficking defect and proteasomal degradation contribute to the phenotype of a novel KCNH2 long QT syndrome mutation.

Mihic A, Chauhan VS, Gao X, Oudit GY, Tsushima RG.

PLoS One. 2011 Mar 31;6(3):e18273. doi: 10.1371/journal.pone.0018273.

20.

hERG K+ channel-associated cardiac effects of the antidepressant drug desipramine.

Staudacher I, Wang L, Wan X, Obers S, Wenzel W, Tristram F, Koschny R, Staudacher K, Kisselbach J, Koelsch P, Schweizer PA, Katus HA, Ficker E, Thomas D.

Naunyn Schmiedebergs Arch Pharmacol. 2011 Feb;383(2):119-39. doi: 10.1007/s00210-010-0583-9. Epub 2010 Dec 1.

PMID:
21120454
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