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Items: 1 to 20 of 97

1.

Mitigation of radiation-induced hematopoietic injury via regulation of cellular MAPK/phosphatase levels and increasing hematopoietic stem cells.

Patwardhan RS, Sharma D, Checker R, Sandur SK.

Free Radic Biol Med. 2014 Mar;68:52-64. doi: 10.1016/j.freeradbiomed.2013.11.004. Epub 2013 Nov 25.

PMID:
24287141
2.

Amelioration of radiation-induced hematopoietic syndrome by an antioxidant chlorophyllin through increased stem cell activity and modulation of hematopoiesis.

Suryavanshi S, Sharma D, Checker R, Thoh M, Gota V, Sandur SK, Sainis KB.

Free Radic Biol Med. 2015 Aug;85:56-70. doi: 10.1016/j.freeradbiomed.2015.04.007. Epub 2015 Apr 11.

PMID:
25872101
3.

Involvement of ERK-Nrf-2 signaling in ionizing radiation induced cell death in normal and tumor cells.

Patwardhan RS, Checker R, Sharma D, Sandur SK, Sainis KB.

PLoS One. 2013 Jun 11;8(6):e65929. doi: 10.1371/journal.pone.0065929. Print 2013.

4.

Baicalein inhibits melanogenesis through activation of the ERK signaling pathway.

Li X, Guo L, Sun Y, Zhou J, Gu Y, Li Y.

Int J Mol Med. 2010 Jun;25(6):923-7.

PMID:
20428797
5.

Pro-oxidants ameliorate radiation-induced apoptosis through activation of the calcium-ERK1/2-Nrf2 pathway.

Khan NM, Sandur SK, Checker R, Sharma D, Poduval TB, Sainis KB.

Free Radic Biol Med. 2011 Jul 1;51(1):115-28. doi: 10.1016/j.freeradbiomed.2011.03.037. Epub 2011 Apr 8.

PMID:
21530647
6.

Baicalein protects against 6-OHDA-induced neurotoxicity through activation of Keap1/Nrf2/HO-1 and involving PKCα and PI3K/AKT signaling pathways.

Zhang Z, Cui W, Li G, Yuan S, Xu D, Hoi MP, Lin Z, Dou J, Han Y, Lee SM.

J Agric Food Chem. 2012 Aug 22;60(33):8171-82. doi: 10.1021/jf301511m. Epub 2012 Aug 9.

PMID:
22838648
7.

Delta-tocotrienol protects mouse and human hematopoietic progenitors from gamma-irradiation through extracellular signal-regulated kinase/mammalian target of rapamycin signaling.

Li XH, Fu D, Latif NH, Mullaney CP, Ney PH, Mog SR, Whitnall MH, Srinivasan V, Xiao M.

Haematologica. 2010 Dec;95(12):1996-2004. doi: 10.3324/haematol.2010.026492. Epub 2010 Sep 7.

9.

Flavonoid baicalein modulates H2O2-induced mitogen-activated protein kinases activation and cell death in SK-N-MC cells.

Moslehi M, Meshkini A, Yazdanparast R.

Cell Mol Neurobiol. 2012 May;32(4):549-60. doi: 10.1007/s10571-011-9795-x. Epub 2012 Jan 14.

PMID:
22246135
10.

MKP3 negatively modulates PDGF-induced Akt and Erk5 phosphorylation as well as chemotaxis.

Razmara M, Eger G, Rorsman C, Heldin CH, Lennartsson J.

Cell Signal. 2012 Mar;24(3):635-40. doi: 10.1016/j.cellsig.2011.11.001. Epub 2011 Nov 9.

PMID:
22100392
11.

Inhibitory effect of baicalein on IL-6-mediated signaling cascades in human myeloma cells.

Liu S, Ma Z, Cai H, Li Q, Rong W, Kawano M.

Eur J Haematol. 2010 Feb 1;84(2):137-44. doi: 10.1111/j.1600-0609.2009.01365.x. Epub 2009 Oct 28.

PMID:
19878271
12.

Sodium orthovanadate (vanadate), a potent mitigator of radiation-induced damage to the hematopoietic system in mice.

Wang B, Tanaka K, Morita A, Ninomiya Y, Maruyama K, Fujita K, Hosoi Y, Nenoi M.

J Radiat Res. 2013 Jul 1;54(4):620-9. doi: 10.1093/jrr/rrs140. Epub 2013 Jan 24.

13.

Baicalein attenuates impaired hippocampal neurogenesis and the neurocognitive deficits induced by γ-ray radiation.

Oh SB, Park HR, Jang YJ, Choi SY, Son TG, Lee J.

Br J Pharmacol. 2013 Jan;168(2):421-31. doi: 10.1111/j.1476-5381.2012.02142.x.

14.

Metformin ameliorates ionizing irradiation-induced long-term hematopoietic stem cell injury in mice.

Xu G, Wu H, Zhang J, Li D, Wang Y, Wang Y, Zhang H, Lu L, Li C, Huang S, Xing Y, Zhou D, Meng A.

Free Radic Biol Med. 2015 Oct;87:15-25. doi: 10.1016/j.freeradbiomed.2015.05.045. Epub 2015 Jun 16.

15.

NRF2-mediated Notch pathway activation enhances hematopoietic reconstitution following myelosuppressive radiation.

Kim JH, Thimmulappa RK, Kumar V, Cui W, Kumar S, Kombairaju P, Zhang H, Margolick J, Matsui W, Macvittie T, Malhotra SV, Biswal S.

J Clin Invest. 2014 Feb;124(2):730-41. doi: 10.1172/JCI70812. Epub 2014 Jan 27.

16.

Baicalein attenuates intimal hyperplasia after rat carotid balloon injury through arresting cell-cycle progression and inhibiting ERK, Akt, and NF-kappaB activity in vascular smooth-muscle cells.

Peng CY, Pan SL, Huang YW, Guh JH, Chang YL, Teng CM.

Naunyn Schmiedebergs Arch Pharmacol. 2008 Dec;378(6):579-88. doi: 10.1007/s00210-008-0328-1. Epub 2008 Jul 29.

PMID:
18663431
17.

The potential benefits of nicaraven to protect against radiation-induced injury in hematopoietic stem/progenitor cells with relative low dose exposures.

Ali H, Galal O, Urata Y, Goto S, Guo CY, Luo L, Abdelrahim E, Ono Y, Mostafa E, Li TS.

Biochem Biophys Res Commun. 2014 Sep 26;452(3):548-53. doi: 10.1016/j.bbrc.2014.08.112. Epub 2014 Aug 28.

PMID:
25173934
18.

Baicalein inhibits the invasion and metastatic capabilities of hepatocellular carcinoma cells via down-regulation of the ERK pathway.

Chen K, Zhang S, Ji Y, Li J, An P, Ren H, Liang R, Yang J, Li Z.

PLoS One. 2013 Sep 6;8(9):e72927. doi: 10.1371/journal.pone.0072927. eCollection 2013.

19.

Activation of the MAP kinase pathway by c-Kit is PI-3 kinase dependent in hematopoietic progenitor/stem cell lines.

Wandzioch E, Edling CE, Palmer RH, Carlsson L, Hallberg B.

Blood. 2004 Jul 1;104(1):51-7. Epub 2004 Mar 2.

20.

The activation of HO-1/Nrf-2 contributes to the protective effects of diallyl disulfide (DADS) against ethanol-induced oxidative stress.

Zeng T, Zhang CL, Song FY, Zhao XL, Yu LH, Zhu ZP, Xie KQ.

Biochim Biophys Acta. 2013 Oct;1830(10):4848-59. doi: 10.1016/j.bbagen.2013.06.028. Epub 2013 Jun 28.

PMID:
23816986
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