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Results: 1 to 20 of 100

1.

Genetic complexity in a Drosophila model of diabetes-associated misfolded human proinsulin.

Park SY, Ludwig MZ, Tamarina NA, He BZ, Carl SH, Dickerson DA, Barse L, Arun B, Williams CL, Miles CM, Philipson LH, Steiner DF, Bell GI, Kreitman M.

Genetics. 2014 Feb;196(2):539-55. doi: 10.1534/genetics.113.157602. Epub 2013 Nov 26.

PMID:
24281154
[PubMed - in process]
Free PMC Article
2.

Effect of genetic variation in a Drosophila model of diabetes-associated misfolded human proinsulin.

He BZ, Ludwig MZ, Dickerson DA, Barse L, Arun B, Vilhjálmsson BJ, Jiang P, Park SY, Tamarina NA, Selleck SB, Wittkopp PJ, Bell GI, Kreitman M.

Genetics. 2014 Feb;196(2):557-67. doi: 10.1534/genetics.113.157800. Epub 2013 Nov 26. Erratum in: Genetics. 2014 Apr;196(4):1357. Jiang, Pengyao [added].

PMID:
24281155
[PubMed - in process]
Free PMC Article
3.

IRE1 inhibition perturbs the unfolded protein response in a pancreatic beta-cell line expressing mutant proinsulin, but does not sensitize the cells to apoptosis.

Zhang L, Nosak C, Sollazzo P, Odisho T, Volchuk A.

BMC Cell Biol. 2014 Jul 10;15(1):29. [Epub ahead of print]

PMID:
25011481
[PubMed - as supplied by publisher]
Free Article
4.

Ectopic expression of BEAF32A in the Drosophila eye imaginal disc inhibits differentiation of photoreceptor cells and induces apoptosis.

Yamaguchi M, Yoshida H, Hirose F, Inoue YH, Hayashi Y, Yamagishi M, Nishi Y, Tamai K, Sakaguchi K, Matsukage A.

Chromosoma. 2001 Sep;110(5):313-21.

PMID:
11685531
[PubMed - indexed for MEDLINE]
5.

Endoplasmic reticulum oxidoreductin-1α (Ero1α) improves folding and secretion of mutant proinsulin and limits mutant proinsulin-induced endoplasmic reticulum stress.

Wright J, Birk J, Haataja L, Liu M, Ramming T, Weiss MA, Appenzeller-Herzog C, Arvan P.

J Biol Chem. 2013 Oct 25;288(43):31010-8. doi: 10.1074/jbc.M113.510065. Epub 2013 Sep 10.

PMID:
24022479
[PubMed - indexed for MEDLINE]
6.

Ectopic expression of human p53 inhibits entry into S phase and induces apoptosis in the Drosophila eye imaginal disc.

Yamaguchi M, Hirose F, Inoue YH, Shiraki M, Hayashi Y, Nishi Y, Matsukage A.

Oncogene. 1999 Nov 18;18(48):6767-75.

PMID:
10597285
[PubMed - indexed for MEDLINE]
Free Article
7.

Ectopic expression of DREF induces DNA synthesis, apoptosis, and unusual morphogenesis in the Drosophila eye imaginal disc: possible interaction with Polycomb and trithorax group proteins.

Hirose F, Ohshima N, Shiraki M, Inoue YH, Taguchi O, Nishi Y, Matsukage A, Yamaguchi M.

Mol Cell Biol. 2001 Nov;21(21):7231-42.

PMID:
11585906
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Endoplasmic reticulum stress response in an INS-1 pancreatic beta-cell line with inducible expression of a folding-deficient proinsulin.

Hartley T, Siva M, Lai E, Teodoro T, Zhang L, Volchuk A.

BMC Cell Biol. 2010 Jul 26;11:59. doi: 10.1186/1471-2121-11-59.

PMID:
20659334
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Mutant INS-gene induced diabetes of youth: proinsulin cysteine residues impose dominant-negative inhibition on wild-type proinsulin transport.

Liu M, Haataja L, Wright J, Wickramasinghe NP, Hua QX, Phillips NF, Barbetti F, Weiss MA, Arvan P.

PLoS One. 2010 Oct 11;5(10):e13333. doi: 10.1371/journal.pone.0013333. Erratum in: PLoS One. 2010;5(10) doi: 10.1371/annotation/6d5e12f2-defc-48b5-84f6-43253f593a2a.

PMID:
20948967
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Defective gap-junctional communication associated with imaginal disc overgrowth and degeneration caused by mutations of the dco gene in Drosophila.

Jursnich VA, Fraser SE, Held LI Jr, Ryerse J, Bryant PJ.

Dev Biol. 1990 Aug;140(2):413-29.

PMID:
2373260
[PubMed - indexed for MEDLINE]
12.

In vitro processing and secretion of mutant insulin proteins that cause permanent neonatal diabetes.

Rajan S, Eames SC, Park SY, Labno C, Bell GI, Prince VE, Philipson LH.

Am J Physiol Endocrinol Metab. 2010 Mar;298(3):E403-10. doi: 10.1152/ajpendo.00592.2009. Epub 2009 Dec 1.

PMID:
19952343
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Mutant proinsulin proteins associated with neonatal diabetes are retained in the endoplasmic reticulum and not efficiently secreted.

Park SY, Ye H, Steiner DF, Bell GI.

Biochem Biophys Res Commun. 2010 Jan 15;391(3):1449-54. doi: 10.1016/j.bbrc.2009.12.090. Epub 2009 Dec 23.

PMID:
20034470
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Molecular, phenotypic, and expression analysis of vein, a gene required for growth of the Drosophila wing disc.

Simcox AA, Grumbling G, Schnepp B, Bennington-Mathias C, Hersperger E, Shearn A.

Dev Biol. 1996 Aug 1;177(2):475-89.

PMID:
8806825
[PubMed - indexed for MEDLINE]
Free Article
15.

Using natural variation in Drosophila to discover previously unknown endoplasmic reticulum stress genes.

Chow CY, Wolfner MF, Clark AG.

Proc Natl Acad Sci U S A. 2013 May 28;110(22):9013-8. doi: 10.1073/pnas.1307125110. Epub 2013 May 10.

PMID:
23667151
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Several levels of EGF receptor signaling during photoreceptor specification in wild-type, Ellipse, and null mutant Drosophila.

Lesokhin AM, Yu SY, Katz J, Baker NE.

Dev Biol. 1999 Jan 1;205(1):129-44.

PMID:
9882502
[PubMed - indexed for MEDLINE]
Free Article
17.

Positional signaling by hedgehog in Drosophila imaginal disc development.

Felsenfeld AL, Kennison JA.

Development. 1995 Jan;121(1):1-10.

PMID:
7867491
[PubMed - indexed for MEDLINE]
Free Article
18.

Transdetermination in the homeotic eye--antenna imaginal disc of Drosophila melanogaster.

Schmid H.

Dev Biol. 1985 Jan;107(1):28-37.

PMID:
3917414
[PubMed - indexed for MEDLINE]
19.

Multiple Allele Approach to the Study of Genes in DROSOPHILA MELANOGASTER That Are Involved in Imaginal Disc Development.

Shearn A, Hersperger G, Hersperger E, Pentz ES, Denker P.

Genetics. 1978 Jun;89(2):355-70.

PMID:
17248839
[PubMed]
Free PMC Article
20.

canoe encodes a novel protein containing a GLGF/DHR motif and functions with Notch and scabrous in common developmental pathways in Drosophila.

Miyamoto H, Nihonmatsu I, Kondo S, Ueda R, Togashi S, Hirata K, Ikegami Y, Yamamoto D.

Genes Dev. 1995 Mar 1;9(5):612-25.

PMID:
7698650
[PubMed - indexed for MEDLINE]
Free Article

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