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Items: 1 to 20 of 182


Translation initiation factors eIF3 and HCR1 control translation termination and stop codon read-through in yeast cells.

Beznosková P, Cuchalová L, Wagner S, Shoemaker CJ, Gunišová S, von der Haar T, Valášek LS.

PLoS Genet. 2013 Nov;9(11):e1003962. doi: 10.1371/journal.pgen.1003962. Epub 2013 Nov 21.


Interaction of the RNP1 motif in PRT1 with HCR1 promotes 40S binding of eukaryotic initiation factor 3 in yeast.

Nielsen KH, Valásek L, Sykes C, Jivotovskaya A, Hinnebusch AG.

Mol Cell Biol. 2006 Apr;26(8):2984-98.


The iron-sulphur protein RNase L inhibitor functions in translation termination.

Khoshnevis S, Gross T, Rotte C, Baierlein C, Ficner R, Krebber H.

EMBO Rep. 2010 Mar;11(3):214-9. doi: 10.1038/embor.2009.272. Epub 2010 Jan 8.


Related eIF3 subunits TIF32 and HCR1 interact with an RNA recognition motif in PRT1 required for eIF3 integrity and ribosome binding.

Valásek L, Phan L, Schoenfeld LW, Valásková V, Hinnebusch AG.

EMBO J. 2001 Feb 15;20(4):891-904.


The indispensable N-terminal half of eIF3j/HCR1 cooperates with its structurally conserved binding partner eIF3b/PRT1-RRM and with eIF1A in stringent AUG selection.

Elantak L, Wagner S, Herrmannová A, Karásková M, Rutkai E, Lukavsky PJ, Valásek L.

J Mol Biol. 2010 Mar 5;396(4):1097-116. doi: 10.1016/j.jmb.2009.12.047. Epub 2010 Jan 11.


The essential ATP-binding cassette protein RLI1 functions in translation by promoting preinitiation complex assembly.

Dong J, Lai R, Nielsen K, Fekete CA, Qiu H, Hinnebusch AG.

J Biol Chem. 2004 Oct 1;279(40):42157-68. Epub 2004 Jul 23.


Translation termination: new factors and insights.

Baierlein C, Krebber H.

RNA Biol. 2010 Sep-Oct;7(5):548-50. Epub 2010 Sep 1.


Rli1/ABCE1 Recycles Terminating Ribosomes and Controls Translation Reinitiation in 3'UTRs In Vivo.

Young DJ, Guydosh NR, Zhang F, Hinnebusch AG, Green R.

Cell. 2015 Aug 13;162(4):872-84. doi: 10.1016/j.cell.2015.07.041.


Eukaryotic release factor 3 is required for multiple turnovers of peptide release catalysis by eukaryotic release factor 1.

Eyler DE, Wehner KA, Green R.

J Biol Chem. 2013 Oct 11;288(41):29530-8. doi: 10.1074/jbc.M113.487090. Epub 2013 Aug 20.


A subcomplex of three eIF3 subunits binds eIF1 and eIF5 and stimulates ribosome binding of mRNA and tRNA(i)Met.

Phan L, Schoenfeld LW, Valásek L, Nielsen KH, Hinnebusch AG.

EMBO J. 2001 Jun 1;20(11):2954-65.


The C-terminal region of eukaryotic translation initiation factor 3a (eIF3a) promotes mRNA recruitment, scanning, and, together with eIF3j and the eIF3b RNA recognition motif, selection of AUG start codons.

Chiu WL, Wagner S, Herrmannová A, Burela L, Zhang F, Saini AK, Valásek L, Hinnebusch AG.

Mol Cell Biol. 2010 Sep;30(18):4415-34. doi: 10.1128/MCB.00280-10. Epub 2010 Jun 28.


Cryoelectron microscopic structures of eukaryotic translation termination complexes containing eRF1-eRF3 or eRF1-ABCE1.

Preis A, Heuer A, Barrio-Garcia C, Hauser A, Eyler DE, Berninghausen O, Green R, Becker T, Beckmann R.

Cell Rep. 2014 Jul 10;8(1):59-65. doi: 10.1016/j.celrep.2014.04.058. Epub 2014 Jul 4.


Translation initiation factor eIF3 promotes programmed stop codon readthrough.

Beznosková P, Wagner S, Jansen ME, von der Haar T, Valášek LS.

Nucleic Acids Res. 2015 May 26;43(10):5099-111. doi: 10.1093/nar/gkv421. Epub 2015 Apr 29.


N-terminal region of Saccharomyces cerevisiae eRF3 is essential for the functioning of the eRF1/eRF3 complex beyond translation termination.

Urakov VN, Valouev IA, Kochneva-Pervukhova NV, Packeiser AN, Vishnevsky AY, Glebov OO, Smirnov VN, Ter-Avanesyan MD.

BMC Mol Biol. 2006 Oct 11;7:34.


Termination of translation in eukaryotes is governed by two interacting polypeptide chain release factors, eRF1 and eRF3.

Zhouravleva G, Frolova L, Le Goff X, Le Guellec R, Inge-Vechtomov S, Kisselev L, Philippe M.

EMBO J. 1995 Aug 15;14(16):4065-72.


Multiple roles for the C-terminal domain of eIF5 in translation initiation complex assembly and GTPase activation.

Asano K, Shalev A, Phan L, Nielsen K, Clayton J, Valásek L, Donahue TF, Hinnebusch AG.

EMBO J. 2001 May 1;20(9):2326-37.

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