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Items: 1 to 20 of 148

1.

Brd4 is displaced from HPV replication factories as they expand and amplify viral DNA.

Sakakibara N, Chen D, Jang MK, Kang DW, Luecke HF, Wu SY, Chiang CM, McBride AA.

PLoS Pathog. 2013;9(11):e1003777. doi: 10.1371/journal.ppat.1003777. Epub 2013 Nov 21.

2.

Recruitment of Brd4 to the human papillomavirus type 16 DNA replication complex is essential for replication of viral DNA.

Wang X, Helfer CM, Pancholi N, Bradner JE, You J.

J Virol. 2013 Apr;87(7):3871-84. doi: 10.1128/JVI.03068-12. Epub 2013 Jan 30.

3.

Evidence supporting a role for TopBP1 and Brd4 in the initiation but not continuation of human papillomavirus 16 E1/E2-mediated DNA replication.

Gauson EJ, Donaldson MM, Dornan ES, Wang X, Bristol M, Bodily JM, Morgan IM.

J Virol. 2015 May;89(9):4980-91. doi: 10.1128/JVI.00335-15. Epub 2015 Feb 18.

4.

Brd4-independent transcriptional repression function of the papillomavirus e2 proteins.

Schweiger MR, Ottinger M, You J, Howley PM.

J Virol. 2007 Sep;81(18):9612-22. Epub 2007 Jul 11.

5.

Papillomavirus genomes associate with BRD4 to replicate at fragile sites in the host genome.

Jang MK, Shen K, McBride AA.

PLoS Pathog. 2014 May 15;10(5):e1004117. doi: 10.1371/journal.ppat.1004117. eCollection 2014 May.

6.

Brd4-mediated nuclear retention of the papillomavirus E2 protein contributes to its stabilization in host cells.

Li J, Li Q, Diaz J, You J.

Viruses. 2014 Jan 20;6(1):319-35. doi: 10.3390/v6010319.

7.

Viral trans-factor independent replication of human papillomavirus genomes.

Pittayakhajonwut D, Angeletti PC.

Virol J. 2010 Jun 10;7:123. doi: 10.1186/1743-422X-7-123.

8.

Analysis of the papillomavirus E2 and bromodomain protein Brd4 interaction using bimolecular fluorescence complementation.

Helfer CM, Wang R, You J.

PLoS One. 2013 Oct 25;8(10):e77994. doi: 10.1371/journal.pone.0077994. eCollection 2013.

9.

Abrogation of the Brd4-positive transcription elongation factor B complex by papillomavirus E2 protein contributes to viral oncogene repression.

Yan J, Li Q, Lievens S, Tavernier J, You J.

J Virol. 2010 Jan;84(1):76-87. doi: 10.1128/JVI.01647-09. Epub .

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12.

The E1 protein of human papillomavirus type 16 is dispensable for maintenance replication of the viral genome.

Egawa N, Nakahara T, Ohno S, Narisawa-Saito M, Yugawa T, Fujita M, Yamato K, Natori Y, Kiyono T.

J Virol. 2012 Mar;86(6):3276-83. doi: 10.1128/JVI.06450-11. Epub 2012 Jan 11.

13.

The E8--E2 gene product of human papillomavirus type 16 represses early transcription and replication but is dispensable for viral plasmid persistence in keratinocytes.

Lace MJ, Anson JR, Thomas GS, Turek LP, Haugen TH.

J Virol. 2008 Nov;82(21):10841-53. doi: 10.1128/JVI.01481-08. Epub 2008 Aug 27.

14.

The human papillomavirus type 8 E2 tethering protein targets the ribosomal DNA loci of host mitotic chromosomes.

Poddar A, Reed SC, McPhillips MG, Spindler JE, McBride AA.

J Virol. 2009 Jan;83(2):640-50. doi: 10.1128/JVI.01936-08. Epub 2008 Nov 12.

15.

The papillomavirus E1 helicase activates a cellular DNA damage response in viral replication foci.

Sakakibara N, Mitra R, McBride AA.

J Virol. 2011 Sep;85(17):8981-95. doi: 10.1128/JVI.00541-11. Epub 2011 Jul 6.

16.

Identification and analysis of papillomavirus E2 protein binding sites in the human genome.

V├Ása L, Sudakov A, Remm M, Ustav M, Kurg R.

J Virol. 2012 Jan;86(1):348-57. doi: 10.1128/JVI.05606-11. Epub 2011 Oct 26.

17.

CCHCR1 interacts specifically with the E2 protein of human papillomavirus type 16 on a surface overlapping BRD4 binding.

Muller M, Demeret C.

PLoS One. 2014 Mar 24;9(3):e92581. doi: 10.1371/journal.pone.0092581. eCollection 2014.

18.

Bromodomain protein Brd4 plays a key role in Merkel cell polyomavirus DNA replication.

Wang X, Li J, Schowalter RM, Jiao J, Buck CB, You J.

PLoS Pathog. 2012;8(11):e1003021. doi: 10.1371/journal.ppat.1003021. Epub 2012 Nov 8.

19.

Phosphorylation of HPV-16 E2 at serine 243 enables binding to Brd4 and mitotic chromosomes.

Chang SW, Liu WC, Liao KY, Tsao YP, Hsu PH, Chen SL.

PLoS One. 2014 Oct 23;9(10):e110882. doi: 10.1371/journal.pone.0110882. eCollection 2014.

20.

Genome-wide siRNA screen identifies SMCX, EP400, and Brd4 as E2-dependent regulators of human papillomavirus oncogene expression.

Smith JA, White EA, Sowa ME, Powell ML, Ottinger M, Harper JW, Howley PM.

Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3752-7. doi: 10.1073/pnas.0914818107. Epub 2010 Feb 2.

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