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Items: 1 to 20 of 120

1.

Use of an avian hepatocyte assay and the avian Toxchip Polymerse chain reaction array for testing prioritization of 16 organic flame retardants.

Porter E, Crump D, Egloff C, Chiu S, Kennedy SW.

Environ Toxicol Chem. 2014 Mar;33(3):573-82. doi: 10.1002/etc.2469. Epub 2014 Jan 24.

PMID:
24273086
2.
3.

Time-dependent effects of the flame retardant tris(1,3-dichloro-2-propyl) phosphate (TDCPP) on mRNA expression, in vitro and in ovo, reveal optimal sampling times for rapidly metabolized compounds.

Farhat A, Crump D, Porter E, Chiu S, Letcher RJ, Su G, Kennedy SW.

Environ Toxicol Chem. 2014 Dec;33(12):2842-9. doi: 10.1002/etc.2755. Epub 2014 Oct 29.

PMID:
25242413
5.

Biochemical and Transcriptomic Effects of Herring Gull Egg Extracts from Variably Contaminated Colonies of the Laurentian Great Lakes in Chicken Hepatocytes.

Crump D, Williams KL, Chiu S, Letcher RJ, Periard L, Kennedy SW.

Environ Sci Technol. 2015 Aug 18;49(16):10190-8. doi: 10.1021/acs.est.5b02745. Epub 2015 Jul 31.

PMID:
26192021
6.

In Ovo effects of two organophosphate flame retardants--TCPP and TDCPP--on pipping success, development, mRNA expression, and thyroid hormone levels in chicken embryos.

Farhat A, Crump D, Chiu S, Williams KL, Letcher RJ, Gauthier LT, Kennedy SW.

Toxicol Sci. 2013 Jul;134(1):92-102. doi: 10.1093/toxsci/kft100. Epub 2013 Apr 29.

7.

Rapid in vitro metabolism of the flame retardant triphenyl phosphate and effects on cytotoxicity and mRNA expression in chicken embryonic hepatocytes.

Su G, Crump D, Letcher RJ, Kennedy SW.

Environ Sci Technol. 2014 Nov 18;48(22):13511-9. doi: 10.1021/es5039547. Epub 2014 Nov 7.

PMID:
25350880
8.

1,2-Dibromo-4-(1,2-dibromoethyl)-cyclohexane and tris(methylphenyl) phosphate cause significant effects on development, mRNA expression, and circulating bile acid concentrations in chicken embryos.

Crump D, Porter E, Egloff C, Williams KL, Letcher RJ, Gauthier LT, Kennedy SW.

Toxicol Appl Pharmacol. 2014 Jun 15;277(3):279-87. doi: 10.1016/j.taap.2014.03.028. Epub 2014 Apr 12.

PMID:
24726521
9.

Photolytic degradation products of two highly brominated flame retardants cause cytotoxicity and mRNA expression alterations in chicken embryonic hepatocytes.

Su G, Letcher RJ, Crump D, Farmahin R, Giesy JP, Kennedy SW.

Environ Sci Technol. 2014 Oct 21;48(20):12039-46. doi: 10.1021/es503399r. Epub 2014 Sep 29.

PMID:
25222814
10.

In vitro and in ovo effects of four brominated flame retardants on toxicity and hepatic mRNA expression in chicken embryos.

Egloff C, Crump D, Chiu S, Manning G, McLaren KK, Cassone CG, Letcher RJ, Gauthier LT, Kennedy SW.

Toxicol Lett. 2011 Nov 10;207(1):25-33. doi: 10.1016/j.toxlet.2011.08.015. Epub 2011 Aug 26.

PMID:
21893176
11.

Tris(2-butoxyethyl)phosphate and triethyl phosphate alter embryonic development, hepatic mRNA expression, thyroid hormone levels, and circulating bile acid concentrations in chicken embryos.

Egloff C, Crump D, Porter E, Williams KL, Letcher RJ, Gauthier LT, Kennedy SW.

Toxicol Appl Pharmacol. 2014 Sep 15;279(3):303-10. doi: 10.1016/j.taap.2014.06.024. Epub 2014 Jul 3.

PMID:
24998971
12.

Pipping success, isomer-specific accumulation, and hepatic mRNA expression in chicken embryos exposed to HBCD.

Crump D, Egloff C, Chiu S, Letcher RJ, Chu S, Kennedy SW.

Toxicol Sci. 2010 Jun;115(2):492-500. doi: 10.1093/toxsci/kfq068. Epub 2010 Mar 3.

13.

Effects of hexabromocyclododecane and polybrominated diphenyl ethers on mRNA expression in chicken (Gallus domesticus) hepatocytes.

Crump D, Chiu S, Egloff C, Kennedy SW.

Toxicol Sci. 2008 Dec;106(2):479-87. doi: 10.1093/toxsci/kfn196. Epub 2008 Sep 12.

14.

Differential expression, induction, and stability of CYP1A4 and CYP1A5 mRNA in chicken and herring gull embryo hepatocytes.

Head JA, Kennedy SW.

Comp Biochem Physiol C Toxicol Pharmacol. 2007 May;145(4):617-24. Epub 2007 Feb 24.

PMID:
17400515
15.

The effects of Dechlorane Plus on toxicity and mRNA expression in chicken embryos: a comparison of in vitro and in ovo approaches.

Crump D, Chiu S, Gauthier LT, Hickey NJ, Letcher RJ, Kennedy SW.

Comp Biochem Physiol C Toxicol Pharmacol. 2011 Aug;154(2):129-34. doi: 10.1016/j.cbpc.2011.04.005. Epub 2011 Apr 22.

PMID:
21539933
16.

Developmental exposure to organophosphate flame retardants elicits overt toxicity and alters behavior in early life stage zebrafish (Danio rerio).

Dishaw LV, Hunter DL, Padnos B, Padilla S, Stapleton HM.

Toxicol Sci. 2014 Dec;142(2):445-54. doi: 10.1093/toxsci/kfu194. Epub 2014 Sep 19.

17.

Use of a Novel Double-Crested Cormorant ToxChip PCR Array and the EROD Assay to Determine Effects of Environmental Contaminants in Primary Hepatocytes.

Crump D, Farhat A, Chiu S, Williams KL, Jones SP, Langlois VS.

Environ Sci Technol. 2016 Mar 15;50(6):3265-74. doi: 10.1021/acs.est.5b06181. Epub 2016 Mar 3.

PMID:
26894911
18.

A reverse transcription-polymerase chain reaction bioassay for avian vitellogenin mRNA.

Lorenzen A, Casley WL, Moon TW.

Toxicol Appl Pharmacol. 2001 Nov 1;176(3):169-80.

PMID:
11714249
19.

2,3,4,7,8-pentachlorodibenzofuran is a more potent cytochrome P4501A inducer than 2,3,7,8-tetrachlorodibenzo-p-dioxin in herring gull hepatocyte cultures.

Hervé JC, Crump DL, McLaren KK, Giesy JP, Zwiernik MJ, Bursian SJ, Kennedy SW.

Environ Toxicol Chem. 2010 Sep;29(9):2088-95. doi: 10.1002/etc.255.

PMID:
20821667
20.

Endocrine disruption potentials of organophosphate flame retardants and related mechanisms in H295R and MVLN cell lines and in zebrafish.

Liu X, Ji K, Choi K.

Aquat Toxicol. 2012 Jun 15;114-115:173-81. doi: 10.1016/j.aquatox.2012.02.019. Epub 2012 Feb 28.

PMID:
22446829
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