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Results: 1 to 20 of 102

Related Citations for PubMed (Select 24269238)

1.

Small molecule glutaminase inhibitors block glutamate release from stimulated microglia.

Thomas AG, O'Driscoll CM, Bressler J, Kaufmann W, Rojas CJ, Slusher BS.

Biochem Biophys Res Commun. 2014 Jan 3;443(1):32-6. doi: 10.1016/j.bbrc.2013.11.043. Epub 2013 Nov 19.

2.

Kinetic characterization of ebselen, chelerythrine and apomorphine as glutaminase inhibitors.

Thomas AG, Rojas C, Tanega C, Shen M, Simeonov A, Boxer MB, Auld DS, Ferraris DV, Tsukamoto T, Slusher BS.

Biochem Biophys Res Commun. 2013 Aug 23;438(2):243-8. doi: 10.1016/j.bbrc.2013.06.110. Epub 2013 Jul 10.

3.

Macrophage-induced neurotoxicity is mediated by glutamate and attenuated by glutaminase inhibitors and gap junction inhibitors.

Yawata I, Takeuchi H, Doi Y, Liang J, Mizuno T, Suzumura A.

Life Sci. 2008 May 23;82(21-22):1111-6. doi: 10.1016/j.lfs.2008.03.010. Epub 2008 Apr 1.

PMID:
18452953
4.

Glutamate production by HIV-1 infected human macrophage is blocked by the inhibition of glutaminase.

Erdmann N, Zhao J, Lopez AL, Herek S, Curthoys N, Hexum TD, Tsukamoto T, Ferraris D, Zheng J.

J Neurochem. 2007 Jul;102(2):539-49.

5.

Mitochondrial glutaminase enhances extracellular glutamate production in HIV-1-infected macrophages: linkage to HIV-1 associated dementia.

Zhao J, Lopez AL, Erichsen D, Herek S, Cotter RL, Curthoys NP, Zheng J.

J Neurochem. 2004 Jan;88(1):169-80.

PMID:
14675161
6.

Blockade of glutamate release from microglia attenuates experimental autoimmune encephalomyelitis in mice.

Shijie J, Takeuchi H, Yawata I, Harada Y, Sonobe Y, Doi Y, Liang J, Hua L, Yasuoka S, Zhou Y, Noda M, Kawanokuchi J, Mizuno T, Suzumura A.

Tohoku J Exp Med. 2009 Feb;217(2):87-92.

7.

Necrotic neurons enhance microglial neurotoxicity through induction of glutaminase by a MyD88-dependent pathway.

Pais TF, Figueiredo C, Peixoto R, Braz MH, Chatterjee S.

J Neuroinflammation. 2008 Oct 9;5:43. doi: 10.1186/1742-2094-5-43.

8.

Glutamate released by Japanese encephalitis virus-infected microglia involves TNF-α signaling and contributes to neuronal death.

Chen CJ, Ou YC, Chang CY, Pan HC, Liao SL, Chen SY, Raung SL, Lai CY.

Glia. 2012 Mar;60(3):487-501. doi: 10.1002/glia.22282. Epub 2011 Dec 5.

PMID:
22144112
9.

Interferon-α regulates glutaminase 1 promoter through STAT1 phosphorylation: relevance to HIV-1 associated neurocognitive disorders.

Zhao L, Huang Y, Tian C, Taylor L, Curthoys N, Wang Y, Vernon H, Zheng J.

PLoS One. 2012;7(3):e32995. doi: 10.1371/journal.pone.0032995. Epub 2012 Mar 30.

10.

Design, synthesis, and pharmacological evaluation of bis-2-(5-phenylacetamido-1,2,4-thiadiazol-2-yl)ethyl sulfide 3 (BPTES) analogs as glutaminase inhibitors.

Shukla K, Ferraris DV, Thomas AG, Stathis M, Duvall B, Delahanty G, Alt J, Rais R, Rojas C, Gao P, Xiang Y, Dang CV, Slusher BS, Tsukamoto T.

J Med Chem. 2012 Dec 13;55(23):10551-63. doi: 10.1021/jm301191p. Epub 2012 Nov 30.

11.

Glutaminase dysregulation in HIV-1-infected human microglia mediates neurotoxicity: relevant to HIV-1-associated neurocognitive disorders.

Huang Y, Zhao L, Jia B, Wu L, Li Y, Curthoys N, Zheng JC.

J Neurosci. 2011 Oct 19;31(42):15195-204. doi: 10.1523/JNEUROSCI.2051-11.2011.

12.

Tumor necrosis factor-alpha induces neurotoxicity via glutamate release from hemichannels of activated microglia in an autocrine manner.

Takeuchi H, Jin S, Wang J, Zhang G, Kawanokuchi J, Kuno R, Sonobe Y, Mizuno T, Suzumura A.

J Biol Chem. 2006 Jul 28;281(30):21362-8. Epub 2006 May 23.

13.

MeCP2 deficiency enhances glutamate release through NF-κB signaling in myeloid derived cells.

O'Driscoll CM, Kaufmann WE, Bressler JP.

J Neuroimmunol. 2013 Dec 15;265(1-2):61-7. doi: 10.1016/j.jneuroim.2013.09.002. Epub 2013 Sep 12.

PMID:
24268627
14.

Proteasome blockers inhibit TNF-alpha release by lipopolysaccharide stimulated macrophages and microglia: implications for HIV-1 dementia.

Fine SM, Maggirwar SB, Elliott PR, Epstein LG, Gelbard HA, Dewhurst S.

J Neuroimmunol. 1999 Mar 1;95(1-2):55-64.

PMID:
10229115
15.

Novel mechanism of inhibition of rat kidney-type glutaminase by bis-2-(5-phenylacetamido-1,2,4-thiadiazol-2-yl)ethyl sulfide (BPTES).

Robinson MM, McBryant SJ, Tsukamoto T, Rojas C, Ferraris DV, Hamilton SK, Hansen JC, Curthoys NP.

Biochem J. 2007 Sep 15;406(3):407-14.

16.

Blockade of microglial glutamate release protects against ischemic brain injury.

Takeuchi H, Jin S, Suzuki H, Doi Y, Liang J, Kawanokuchi J, Mizuno T, Sawada M, Suzumura A.

Exp Neurol. 2008 Nov;214(1):144-6. doi: 10.1016/j.expneurol.2008.08.001. Epub 2008 Aug 16.

PMID:
18775425
17.
18.

The synthetic triterpenoid CDDO-methyl ester modulates microglial activities, inhibits TNF production, and provides dopaminergic neuroprotection.

Tran TA, McCoy MK, Sporn MB, Tansey MG.

J Neuroinflammation. 2008 May 12;5:14. doi: 10.1186/1742-2094-5-14.

19.

In vitro glutaminase regulation and mechanisms of glutamate generation in HIV-1-infected macrophage.

Erdmann N, Tian C, Huang Y, Zhao J, Herek S, Curthoys N, Zheng J.

J Neurochem. 2009 Apr;109(2):551-61. doi: 10.1111/j.1471-4159.2009.05989.x. Epub 2009 Feb 13.

20.

HIV-infected macrophages mediate neuronal apoptosis through mitochondrial glutaminase.

Tian C, Erdmann N, Zhao J, Cao Z, Peng H, Zheng J.

J Neurochem. 2008 May;105(3):994-1005. Epub 2007 Dec 18.

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