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Results: 1 to 20 of 116

2.

Longikaurin A, a natural ent-kaurane, induces G2/M phase arrest via downregulation of Skp2 and apoptosis induction through ROS/JNK/c-Jun pathway in hepatocellular carcinoma cells.

Liao YJ, Bai HY, Li ZH, Zou J, Chen JW, Zheng F, Zhang JX, Mai SJ, Zeng MS, Sun HD, Pu JX, Xie D.

Cell Death Dis. 2014 Mar 20;5:e1137. doi: 10.1038/cddis.2014.66.

PMID:
24651440
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

2'-Nitroflavone induces apoptosis and modulates mitogen-activated protein kinase pathways in human leukaemia cells.

Cárdenas MG, Blank VC, Marder MN, Roguin LP.

Anticancer Drugs. 2012 Sep;23(8):815-26. doi: 10.1097/CAD.0b013e328353f947.

PMID:
22555195
[PubMed - indexed for MEDLINE]
4.

GL-V9, a newly synthetic flavonoid derivative, induces mitochondrial-mediated apoptosis and G2/M cell cycle arrest in human hepatocellular carcinoma HepG2 cells.

Li L, Lu N, Dai Q, Wei L, Zhao Q, Li Z, He Q, Dai Y, Guo Q.

Eur J Pharmacol. 2011 Nov 16;670(1):13-21. doi: 10.1016/j.ejphar.2011.08.054. Epub 2011 Sep 17.

PMID:
21944925
[PubMed - indexed for MEDLINE]
5.

Bufotalin from Venenum Bufonis inhibits growth of multidrug resistant HepG2 cells through G2/M cell cycle arrest and apoptosis.

Zhang DM, Liu JS, Tang MK, Yiu A, Cao HH, Jiang L, Chan JY, Tian HY, Fung KP, Ye WC.

Eur J Pharmacol. 2012 Oct 5;692(1-3):19-28. doi: 10.1016/j.ejphar.2012.06.045. Epub 2012 Jul 25.

PMID:
22841670
[PubMed - indexed for MEDLINE]
6.

Millepachine, a novel chalcone, induces G2/M arrest by inhibiting CDK1 activity and causing apoptosis via ROS-mitochondrial apoptotic pathway in human hepatocarcinoma cells in vitro and in vivo.

Wu W, Ye H, Wan L, Han X, Wang G, Hu J, Tang M, Duan X, Fan Y, He S, Huang L, Pei H, Wang X, Li X, Xie C, Zhang R, Yuan Z, Mao Y, Wei Y, Chen L.

Carcinogenesis. 2013 Jul;34(7):1636-43. doi: 10.1093/carcin/bgt087. Epub 2013 Mar 7.

PMID:
23471882
[PubMed - indexed for MEDLINE]
Free Article
7.

Anti-tumor effect of germacrone on human hepatoma cell lines through inducing G2/M cell cycle arrest and promoting apoptosis.

Liu Y, Wang W, Fang B, Ma F, Zheng Q, Deng P, Zhao S, Chen M, Yang G, He G.

Eur J Pharmacol. 2013 Jan 5;698(1-3):95-102. doi: 10.1016/j.ejphar.2012.10.013. Epub 2012 Oct 29.

PMID:
23117090
[PubMed - indexed for MEDLINE]
8.

Osthole induces G2/M cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells.

Chao X, Zhou X, Zheng G, Dong C, Zhang W, Song X, Jin T.

Pharm Biol. 2014 May;52(5):544-50. doi: 10.3109/13880209.2013.850517. Epub 2013 Nov 15.

PMID:
24236568
[PubMed - indexed for MEDLINE]
9.

6-Dehydrogingerdione, an active constituent of dietary ginger, induces cell cycle arrest and apoptosis through reactive oxygen species/c-Jun N-terminal kinase pathways in human breast cancer cells.

Hsu YL, Chen CY, Hou MF, Tsai EM, Jong YJ, Hung CH, Kuo PL.

Mol Nutr Food Res. 2010 Sep;54(9):1307-17. doi: 10.1002/mnfr.200900125.

PMID:
20175081
[PubMed - indexed for MEDLINE]
10.

DICO, a novel nonaromatic B-ring flavonoid, induces G2/M cell cycle arrest and apoptosis in human hepatoma cells.

Zhou D, Wei A, Cao C, Ruan J.

Food Chem Toxicol. 2013 Jul;57:322-9. doi: 10.1016/j.fct.2013.03.032. Epub 2013 Apr 6.

PMID:
23567243
[PubMed - indexed for MEDLINE]
11.

Induction of Fas-mediated extrinsic apoptosis, p21WAF1-related G2/M cell cycle arrest and ROS generation by costunolide in estrogen receptor-negative breast cancer cells, MDA-MB-231.

Choi YK, Seo HS, Choi HS, Choi HS, Kim SR, Shin YC, Ko SG.

Mol Cell Biochem. 2012 Apr;363(1-2):119-28. doi: 10.1007/s11010-011-1164-z. Epub 2011 Dec 7.

PMID:
22147197
[PubMed - indexed for MEDLINE]
12.

BML-275, an AMPK inhibitor, induces DNA damage, G2/M arrest and apoptosis in human pancreatic cancer cells.

Duong HQ, Hwang JS, Kim HJ, Seong YS, Bae I.

Int J Oncol. 2012 Dec;41(6):2227-36. doi: 10.3892/ijo.2012.1672. Epub 2012 Oct 17.

PMID:
23076030
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Plumbagin induces cell cycle arrest and apoptosis through reactive oxygen species/c-Jun N-terminal kinase pathways in human melanoma A375.S2 cells.

Wang CC, Chiang YM, Sung SC, Hsu YL, Chang JK, Kuo PL.

Cancer Lett. 2008 Jan 18;259(1):82-98. Epub 2007 Nov 19.

PMID:
18023967
[PubMed - indexed for MEDLINE]
14.

Benzyl isothiocyanate (BITC) induces G2/M phase arrest and apoptosis in human melanoma A375.S2 cells through reactive oxygen species (ROS) and both mitochondria-dependent and death receptor-mediated multiple signaling pathways.

Huang SH, Wu LW, Huang AC, Yu CC, Lien JC, Huang YP, Yang JS, Yang JH, Hsiao YP, Wood WG, Yu CS, Chung JG.

J Agric Food Chem. 2012 Jan 18;60(2):665-75. doi: 10.1021/jf204193v. Epub 2012 Jan 6.

PMID:
22148415
[PubMed - indexed for MEDLINE]
15.

Involvement of histone H3 phosphorylation through p38 MAPK pathway activation in casticin-induced cytocidal effects against the human promyelocytic cell line HL-60.

Kikuchi H, Yuan B, Yuhara E, Takagi N, Toyoda H.

Int J Oncol. 2013 Dec;43(6):2046-56. doi: 10.3892/ijo.2013.2106. Epub 2013 Sep 20.

PMID:
24064676
[PubMed - indexed for MEDLINE]
16.

Oridonin induces G2/M cell cycle arrest and apoptosis through MAPK and p53 signaling pathways in HepG2 cells.

Wang H, Ye Y, Chui JH, Zhu GY, Li YW, Fong DW, Yu ZL.

Oncol Rep. 2010 Sep;24(3):647-51.

PMID:
20664969
[PubMed - indexed for MEDLINE]
17.

Apoptosis induced by a new flavonoid in human hepatoma HepG2 cells involves reactive oxygen species-mediated mitochondrial dysfunction and MAPK activation.

Liu H, Xiao Y, Xiong C, Wei A, Ruan J.

Eur J Pharmacol. 2011 Mar 11;654(3):209-16. doi: 10.1016/j.ejphar.2010.12.036. Epub 2011 Jan 15.

PMID:
21241688
[PubMed - indexed for MEDLINE]
18.
20.

8-Bromo-7-methoxychrysin-induced apoptosis of hepatocellular carcinoma cells involves ROS and JNK.

Yang XH, Zheng X, Cao JG, Xiang HL, Liu F, Lv Y.

World J Gastroenterol. 2010 Jul 21;16(27):3385-93.

PMID:
20632440
[PubMed - indexed for MEDLINE]
Free PMC Article
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