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Results: 1 to 20 of 99

1.

Lentivirus vector-mediated Rho guanine nucleotide dissociation inhibitor 2 overexpression induces beta-2 adrenergic receptor desensitization in airway smooth muscle cells.

Ni S, Zhang Y, Wang H, Zhou J, Ding L, Liu H.

J Thorac Dis. 2013 Oct;5(5):658-66. doi: 10.3978/j.issn.2072-1439.2013.10.07.

PMID:
24255780
[PubMed]
Free PMC Article
2.
3.

Construction of a cell model of β2-adrenoceptor downregulation.

Liu H, Chen Y, Li J, Zhang W, Ni S.

J Thorac Dis. 2013 Aug;5(4):492-7. doi: 10.3978/j.issn.2072-1439.2013.08.32.

PMID:
23991307
[PubMed]
Free PMC Article
4.

Mechanisms of acute desensitization of the beta2AR-adenylyl cyclase pathway in human airway smooth muscle.

Penn RB, Panettieri RA Jr, Benovic JL.

Am J Respir Cell Mol Biol. 1998 Aug;19(2):338-48.

PMID:
9698608
[PubMed - indexed for MEDLINE]
5.
6.

Regulation of membrane targeting of the G protein-coupled receptor kinase 2 by protein kinase A and its anchoring protein AKAP79.

Cong M, Perry SJ, Lin FT, Fraser ID, Hu LA, Chen W, Pitcher JA, Scott JD, Lefkowitz RJ.

J Biol Chem. 2001 May 4;276(18):15192-9. Epub 2001 Jan 22.

PMID:
11278469
[PubMed - indexed for MEDLINE]
Free Article
7.

Mechanism regulating proasthmatic effects of prolonged homologous beta2-adrenergic receptor desensitization in airway smooth muscle.

Nino G, Hu A, Grunstein JS, Grunstein MM.

Am J Physiol Lung Cell Mol Physiol. 2009 Oct;297(4):L746-57. doi: 10.1152/ajplung.00079.2009. Epub 2009 Aug 7.

PMID:
19666775
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Cytokines regulate beta-2-adrenergic receptor responsiveness in airway smooth muscle via multiple PKA- and EP2 receptor-dependent mechanisms.

Guo M, Pascual RM, Wang S, Fontana MF, Valancius CA, Panettieri RA Jr, Tilley SL, Penn RB.

Biochemistry. 2005 Oct 25;44(42):13771-82.

PMID:
16229467
[PubMed - indexed for MEDLINE]
9.

Increased RhoGDI2 and peroxiredoxin 5 levels in asthmatic murine model of beta2-adrenoceptor desensitization: a proteomics approach.

Liu H, Zhou LF, Zhang Q, Qian FH, Yin KS, Huang M, Zhang XL.

Chin Med J (Engl). 2008 Feb 20;121(4):355-62.

PMID:
18304470
[PubMed - indexed for MEDLINE]
Free Article
10.

Extracellular signal-regulated kinase activation in airway smooth muscle cell proliferation in chronic asthmatic rats.

Bai J, Liu XS, Xu YJ, Zhang ZX, Xie M, Ni W.

Sheng Li Xue Bao. 2007 Jun 25;59(3):311-8.

PMID:
17579786
[PubMed - indexed for MEDLINE]
Free Article
11.

A dominant negative mutant of the G protein-coupled receptor kinase 2 selectively attenuates adenosine A2 receptor desensitization.

Mundell SJ, Benovic JL, Kelly E.

Mol Pharmacol. 1997 Jun;51(6):991-8.

PMID:
9187265
[PubMed - indexed for MEDLINE]
Free Article
12.

Functional receptor coupling to Gi is a mechanism of agonist-promoted desensitization of the beta2-adrenergic receptor.

Tepe NM, Liggett SB.

J Recept Signal Transduct Res. 2000 Jan;20(1):75-85.

PMID:
10711498
[PubMed - indexed for MEDLINE]
13.

Enhanced expression of G protein-coupled receptor kinase 2 selectively increases the sensitivity of A2A adenosine receptors to agonist-induced desensitization.

Mundell SJ, Luty JS, Willets J, Benovic JL, Kelly E.

Br J Pharmacol. 1998 Sep;125(2):347-56.

PMID:
9786508
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Clinical significance of Rho GDP dissociation inhibitor 2 in colorectal carcinoma.

Fujita A, Shida A, Fujioka S, Kurihara H, Okamoto T, Yanaga K.

Int J Clin Oncol. 2012 Apr;17(2):137-42. doi: 10.1007/s10147-011-0270-y. Epub 2011 Jun 24.

PMID:
21698524
[PubMed - indexed for MEDLINE]
15.

Synergistic regulation of beta2-adrenergic receptor sequestration: intracellular complement of beta-adrenergic receptor kinase and beta-arrestin determine kinetics of internalization.

Ménard L, Ferguson SS, Zhang J, Lin FT, Lefkowitz RJ, Caron MG, Barak LS.

Mol Pharmacol. 1997 May;51(5):800-8.

PMID:
9145918
[PubMed - indexed for MEDLINE]
Free Article
16.

Effect of tumor suppressor PTEN gene on apoptosis and cell cycle of human airway smooth muscle cells.

Luo L, Gong YQ, Qi X, Lai W, Lan H, Luo Y.

Mol Cell Biochem. 2013 Mar;375(1-2):1-9. doi: 10.1007/s11010-012-1484-7. Epub 2012 Dec 29.

PMID:
23275086
[PubMed - indexed for MEDLINE]
17.

Alveolar epithelial type I cells express beta2-adrenergic receptors and G-protein receptor kinase 2.

Liebler JM, Borok Z, Li X, Zhou B, Sandoval AJ, Kim KJ, Crandall ED.

J Histochem Cytochem. 2004 Jun;52(6):759-67.

PMID:
15150284
[PubMed - indexed for MEDLINE]
18.

Endogenous Gs-coupled receptors in smooth muscle exhibit differential susceptibility to GRK2/3-mediated desensitization.

Kong KC, Gandhi U, Martin TJ, Anz CB, Yan H, Misior AM, Pascual RM, Deshpande DA, Penn RB.

Biochemistry. 2008 Sep 2;47(35):9279-88. doi: 10.1021/bi801056w. Epub 2008 Aug 9.

PMID:
18690720
[PubMed - indexed for MEDLINE]
Free PMC Article
19.
20.

Selective reduction in A2 adenosine receptor desensitization following antisense-induced suppression of G protein-coupled receptor kinase 2 expression.

Willets JM, Parent JL, Benovic JL, Kelly E.

J Neurochem. 1999 Nov;73(5):1781-9.

PMID:
10537035
[PubMed - indexed for MEDLINE]

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