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Items: 1 to 20 of 100

1.

Genetic regulation of vesiculogenesis and immunomodulation in Mycobacterium tuberculosis.

Rath P, Huang C, Wang T, Wang T, Li H, Prados-Rosales R, Elemento O, Casadevall A, Nathan CF.

Proc Natl Acad Sci U S A. 2013 Dec 3;110(49):E4790-7. doi: 10.1073/pnas.1320118110. Epub 2013 Nov 18.

2.

TLR2 and its co-receptors determine responses of macrophages and dendritic cells to lipoproteins of Mycobacterium tuberculosis.

Drage MG, Pecora ND, Hise AG, Febbraio M, Silverstein RL, Golenbock DT, Boom WH, Harding CV.

Cell Immunol. 2009;258(1):29-37. doi: 10.1016/j.cellimm.2009.03.008. Epub 2009 Apr 11.

3.

Mycobacterium tuberculosis LprA is a lipoprotein agonist of TLR2 that regulates innate immunity and APC function.

Pecora ND, Gehring AJ, Canaday DH, Boom WH, Harding CV.

J Immunol. 2006 Jul 1;177(1):422-9.

5.

Functional dissection of protein domains involved in the immunomodulatory properties of PE_PGRS33 of Mycobacterium tuberculosis.

Zumbo A, Palucci I, Cascioferro A, Sali M, Ventura M, D'Alfonso P, Iantomasi R, Di Sante G, Ria F, Sanguinetti M, Fadda G, Manganelli R, Delogu G.

Pathog Dis. 2013 Dec;69(3):232-9. doi: 10.1111/2049-632X.12096. Epub 2013 Oct 7.

7.

Containment of aerogenic Mycobacterium tuberculosis infection in mice does not require MyD88 adaptor function for TLR2, -4 and -9.

Hölscher C, Reiling N, Schaible UE, Hölscher A, Bathmann C, Korbel D, Lenz I, Sonntag T, Kröger S, Akira S, Mossmann H, Kirschning CJ, Wagner H, Freudenberg M, Ehlers S.

Eur J Immunol. 2008 Mar;38(3):680-94. doi: 10.1002/eji.200736458.

8.

Mycobacteria release active membrane vesicles that modulate immune responses in a TLR2-dependent manner in mice.

Prados-Rosales R, Baena A, Martinez LR, Luque-Garcia J, Kalscheuer R, Veeraraghavan U, Camara C, Nosanchuk JD, Besra GS, Chen B, Jimenez J, Glatman-Freedman A, Jacobs WR Jr, Porcelli SA, Casadevall A.

J Clin Invest. 2011 Apr;121(4):1471-83. doi: 10.1172/JCI44261.

10.

Toll-like receptor 2-dependent inhibition of macrophage class II MHC expression and antigen processing by 19-kDa lipoprotein of Mycobacterium tuberculosis.

Noss EH, Pai RK, Sellati TJ, Radolf JD, Belisle J, Golenbock DT, Boom WH, Harding CV.

J Immunol. 2001 Jul 15;167(2):910-8.

11.

Bacterial Membrane Vesicles Mediate the Release of Mycobacterium tuberculosis Lipoglycans and Lipoproteins from Infected Macrophages.

Athman JJ, Wang Y, McDonald DJ, Boom WH, Harding CV, Wearsch PA.

J Immunol. 2015 Aug 1;195(3):1044-53. doi: 10.4049/jimmunol.1402894. Epub 2015 Jun 24.

PMID:
26109643
12.

Mycobacterium tuberculosis lipoprotein LprG (Rv1411c) binds triacylated glycolipid agonists of Toll-like receptor 2.

Drage MG, Tsai HC, Pecora ND, Cheng TY, Arida AR, Shukla S, Rojas RE, Seshadri C, Moody DB, Boom WH, Sacchettini JC, Harding CV.

Nat Struct Mol Biol. 2010 Sep;17(9):1088-95. doi: 10.1038/nsmb.1869. Epub 2010 Aug 8.

13.

Mycobacterium tuberculosis lipoprotein-induced association of TLR2 with protein kinase C zeta in lipid rafts contributes to reactive oxygen species-dependent inflammatory signalling in macrophages.

Shin DM, Yang CS, Lee JY, Lee SJ, Choi HH, Lee HM, Yuk JM, Harding CV, Jo EK.

Cell Microbiol. 2008 Sep;10(9):1893-905. doi: 10.1111/j.1462-5822.2008.01179.x. Epub 2008 Jul 15.

15.

Mycobacterium tuberculosis inhibits macrophage responses to IFN-gamma through myeloid differentiation factor 88-dependent and -independent mechanisms.

Fortune SM, Solache A, Jaeger A, Hill PJ, Belisle JT, Bloom BR, Rubin EJ, Ernst JD.

J Immunol. 2004 May 15;172(10):6272-80.

16.

TLR2 engagement on CD4(+) T cells enhances effector functions and protective responses to Mycobacterium tuberculosis.

Reba SM, Li Q, Onwuzulike S, Ding X, Karim AF, Hernandez Y, Fulton SA, Harding CV, Lancioni CL, Nagy N, Rodriguez ME, Wearsch PA, Rojas RE.

Eur J Immunol. 2014 May;44(5):1410-21. doi: 10.1002/eji.201344100. Epub 2014 Mar 14.

17.

Mycobacterium tuberculosis lipoproteins directly regulate human memory CD4(+) T cell activation via Toll-like receptors 1 and 2.

Lancioni CL, Li Q, Thomas JJ, Ding X, Thiel B, Drage MG, Pecora ND, Ziady AG, Shank S, Harding CV, Boom WH, Rojas RE.

Infect Immun. 2011 Feb;79(2):663-73. doi: 10.1128/IAI.00806-10. Epub 2010 Nov 15.

18.

Navigating through the maze of TLR2 mediated signaling network for better mycobacterium infection control.

Yu X, Zeng J, Xie J.

Biochimie. 2014 Jul;102:1-8. doi: 10.1016/j.biochi.2014.02.012. Epub 2014 Mar 2. Review.

PMID:
24594065
19.
20.

Host defense and recruitment of Foxp3⁺ T regulatory cells to the lungs in chronic Mycobacterium tuberculosis infection requires toll-like receptor 2.

McBride A, Konowich J, Salgame P.

PLoS Pathog. 2013;9(6):e1003397. doi: 10.1371/journal.ppat.1003397. Epub 2013 Jun 13.

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