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Results: 1 to 20 of 94

1.

Metabolic reconstruction identifies strain-specific regulation of virulence in Toxoplasma gondii.

Song C, Chiasson MA, Nursimulu N, Hung SS, Wasmuth J, Grigg ME, Parkinson J.

Mol Syst Biol. 2013 Nov 19;9:708. doi: 10.1038/msb.2013.62.

PMID:
24247825
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Transcriptional analysis of murine macrophages infected with different Toxoplasma strains identifies novel regulation of host signaling pathways.

Melo MB, Nguyen QP, Cordeiro C, Hassan MA, Yang N, McKell R, Rosowski EE, Julien L, Butty V, Dardé ML, Ajzenberg D, Fitzgerald K, Young LH, Saeij JP.

PLoS Pathog. 2013;9(12):e1003779. doi: 10.1371/journal.ppat.1003779. Epub 2013 Dec 19.

PMID:
24367253
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Apicoplast isoprenoid precursor synthesis and the molecular basis of fosmidomycin resistance in Toxoplasma gondii.

Nair SC, Brooks CF, Goodman CD, Sturm A, McFadden GI, Sundriyal S, Anglin JL, Song Y, Moreno SN, Striepen B.

J Exp Med. 2011 Jul 4;208(7):1547-59. doi: 10.1084/jem.20110039. Epub 2011 Jun 20. Erratum in: J Exp Med. 2012 May 7;209(5):1051. Strurm, Angelika [corrected to Sturm, Angelika].

PMID:
21690250
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Strain-dependent host transcriptional responses to Toxoplasma infection are largely conserved in mammalian and avian hosts.

Ong YC, Boyle JP, Boothroyd JC.

PLoS One. 2011;6(10):e26369. doi: 10.1371/journal.pone.0026369. Epub 2011 Oct 13.

PMID:
22022607
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Genetic basis for phenotypic differences between different Toxoplasma gondii type I strains.

Yang N, Farrell A, Niedelman W, Melo M, Lu D, Julien L, Marth GT, Gubbels MJ, Saeij JP.

BMC Genomics. 2013 Jul 10;14:467. doi: 10.1186/1471-2164-14-467.

PMID:
23837824
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Differences among the three major strains of Toxoplasma gondii and their specific interactions with the infected host.

Saeij JP, Boyle JP, Boothroyd JC.

Trends Parasitol. 2005 Oct;21(10):476-81. Review.

PMID:
16098810
[PubMed - indexed for MEDLINE]
7.

Phosphorylation of mouse immunity-related GTPase (IRG) resistance proteins is an evasion strategy for virulent Toxoplasma gondii.

Steinfeldt T, Könen-Waisman S, Tong L, Pawlowski N, Lamkemeyer T, Sibley LD, Hunn JP, Howard JC.

PLoS Biol. 2010 Dec 21;8(12):e1000576. doi: 10.1371/journal.pbio.1000576.

PMID:
21203588
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Expression variance, biochemical and immunological properties of Toxoplasma gondii dense granule protein GRA7.

Neudeck A, Stachelhaus S, Nischik N, Striepen B, Reichmann G, Fischer HG.

Microbes Infect. 2002 May;4(6):581-90.

PMID:
12048027
[PubMed - indexed for MEDLINE]
9.

Comparative genomics of the apicomplexan parasites Toxoplasma gondii and Neospora caninum: Coccidia differing in host range and transmission strategy.

Reid AJ, Vermont SJ, Cotton JA, Harris D, Hill-Cawthorne GA, Könen-Waisman S, Latham SM, Mourier T, Norton R, Quail MA, Sanders M, Shanmugam D, Sohal A, Wasmuth JD, Brunk B, Grigg ME, Howard JC, Parkinson J, Roos DS, Trees AJ, Berriman M, Pain A, Wastling JM.

PLoS Pathog. 2012;8(3):e1002567. doi: 10.1371/journal.ppat.1002567. Epub 2012 Mar 22.

PMID:
22457617
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Hammondia hammondi, an avirulent relative of Toxoplasma gondii, has functional orthologs of known T. gondii virulence genes.

Walzer KA, Adomako-Ankomah Y, Dam RA, Herrmann DC, Schares G, Dubey JP, Boyle JP.

Proc Natl Acad Sci U S A. 2013 Apr 30;110(18):7446-51. doi: 10.1073/pnas.1304322110. Epub 2013 Apr 15.

PMID:
23589877
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Changes in the expression of human cell division autoantigen-1 influence Toxoplasma gondii growth and development.

Radke JR, Donald RG, Eibs A, Jerome ME, Behnke MS, Liberator P, White MW.

PLoS Pathog. 2006 Oct;2(10):e105.

PMID:
17069459
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

In vitro generation of novel pyrimethamine resistance mutations in the Toxoplasma gondii dihydrofolate reductase.

Reynolds MG, Oh J, Roos DS.

Antimicrob Agents Chemother. 2001 Apr;45(4):1271-7.

PMID:
11257045
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Determination of stage interconversion in vitro and in vivo by construction of transgenic Toxoplasma gondii that stably express stage-specific fluorescent proteins.

Zhang H, Zhang Y, Cao J, Zhou Y, Wang N, Zhou J.

Exp Parasitol. 2013 Jul;134(3):275-80. doi: 10.1016/j.exppara.2013.03.015. Epub 2013 Mar 29.

PMID:
23545429
[PubMed - indexed for MEDLINE]
14.

Population structure and mouse-virulence of Toxoplasma gondii in Brazil.

Pena HF, Gennari SM, Dubey JP, Su C.

Int J Parasitol. 2008 Apr;38(5):561-9. Epub 2007 Sep 21.

PMID:
17963770
[PubMed - indexed for MEDLINE]
15.

Host cells participate in the in vitro effects of novel diamidine analogues against tachyzoites of the intracellular apicomplexan parasites Neospora caninum and Toxoplasma gondii.

Leepin A, Stüdli A, Brun R, Stephens CE, Boykin DW, Hemphill A.

Antimicrob Agents Chemother. 2008 Jun;52(6):1999-2008. doi: 10.1128/AAC.01236-07. Epub 2008 Mar 24.

PMID:
18362190
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Integrated bioinformatic and targeted deletion analyses of the SRS gene superfamily identify SRS29C as a negative regulator of Toxoplasma virulence.

Wasmuth JD, Pszenny V, Haile S, Jansen EM, Gast AT, Sher A, Boyle JP, Boulanger MJ, Parkinson J, Grigg ME.

MBio. 2012 Nov 13;3(6). pii: e00321-12. doi: 10.1128/mBio.00321-12.

PMID:
23149485
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Determinants of GBP recruitment to Toxoplasma gondii vacuoles and the parasitic factors that control it.

Virreira Winter S, Niedelman W, Jensen KD, Rosowski EE, Julien L, Spooner E, Caradonna K, Burleigh BA, Saeij JP, Ploegh HL, Frickel EM.

PLoS One. 2011;6(9):e24434. doi: 10.1371/journal.pone.0024434. Epub 2011 Sep 8.

PMID:
21931713
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Polymorphic family of injected pseudokinases is paramount in Toxoplasma virulence.

Reese ML, Zeiner GM, Saeij JP, Boothroyd JC, Boyle JP.

Proc Natl Acad Sci U S A. 2011 Jun 7;108(23):9625-30. doi: 10.1073/pnas.1015980108. Epub 2011 Mar 21.

PMID:
21436047
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Infection of mice by a Toxoplasma gondii isolate from an AIDS patient: virulence and activation of hosts' immune responses are independent of parasite genotype.

Haque S, Hanna S, Gharbi S, Franck J, Dumon H, Haque A.

Parasite Immunol. 1999 Dec;21(12):649-57.

PMID:
10583867
[PubMed - indexed for MEDLINE]
20.

Optogenetic modulation of an adenylate cyclase in Toxoplasma gondii demonstrates a requirement of the parasite cAMP for host-cell invasion and stage differentiation.

Hartmann A, Arroyo-Olarte RD, Imkeller K, Hegemann P, Lucius R, Gupta N.

J Biol Chem. 2013 May 10;288(19):13705-17. doi: 10.1074/jbc.M113.465583. Epub 2013 Mar 22.

PMID:
23525100
[PubMed - indexed for MEDLINE]
Free PMC Article

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