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Items: 1 to 20 of 103


Lamellipodin and the Scar/WAVE complex cooperate to promote cell migration in vivo.

Law AL, Vehlow A, Kotini M, Dodgson L, Soong D, Theveneau E, Bodo C, Taylor E, Navarro C, Perera U, Michael M, Dunn GA, Bennett D, Mayor R, Krause M.

J Cell Biol. 2013 Nov 25;203(4):673-89. doi: 10.1083/jcb.201304051. Epub 2013 Nov 18.


Sra-1 and Nap1 link Rac to actin assembly driving lamellipodia formation.

Steffen A, Rottner K, Ehinger J, Innocenti M, Scita G, Wehland J, Stradal TE.

EMBO J. 2004 Feb 25;23(4):749-59. Epub 2004 Feb 5.


Membrane targeting of WAVE2 is not sufficient for WAVE2-dependent actin polymerization: a role for IRSp53 in mediating the interaction between Rac and WAVE2.

Abou-Kheir W, Isaac B, Yamaguchi H, Cox D.

J Cell Sci. 2008 Feb 1;121(Pt 3):379-90. doi: 10.1242/jcs.010272. Epub 2008 Jan 15.


HSPC300 and its role in neuronal connectivity.

Qurashi A, Sahin HB, Carrera P, Gautreau A, Schenck A, Giangrande A.

Neural Dev. 2007 Sep 25;2:18.


Clathrin is required for Scar/Wave-mediated lamellipodium formation.

Gautier JJ, Lomakina ME, Bouslama-Oueghlani L, Derivery E, Beilinson H, Faigle W, Loew D, Louvard D, Echard A, Alexandrova AY, Baum B, Gautreau A.

J Cell Sci. 2011 Oct 15;124(Pt 20):3414-27. doi: 10.1242/jcs.081083.


SrGAP3 interacts with lamellipodin at the cell membrane and regulates Rac-dependent cellular protrusions.

Endris V, Haussmann L, Buss E, Bacon C, Bartsch D, Rappold G.

J Cell Sci. 2011 Dec 1;124(Pt 23):3941-55. doi: 10.1242/jcs.077081. Epub 2011 Dec 8.


IRSp53 is an essential intermediate between Rac and WAVE in the regulation of membrane ruffling.

Miki H, Yamaguchi H, Suetsugu S, Takenawa T.

Nature. 2000 Dec 7;408(6813):732-5.


Abp1 utilizes the Arp2/3 complex activator Scar/WAVE in bristle development.

Koch N, Dharmalingam E, Westermann M, Qualmann B, Thomas U, Kessels MM.

J Cell Sci. 2012 Aug 1;125(Pt 15):3578-89. Epub 2012 Mar 30.


Two distinct modes of guidance signalling during collective migration of border cells.

Bianco A, Poukkula M, Cliffe A, Mathieu J, Luque CM, Fulga TA, Rørth P.

Nature. 2007 Jul 19;448(7151):362-5.


ERK-MAPK drives lamellipodia protrusion by activating the WAVE2 regulatory complex.

Mendoza MC, Er EE, Zhang W, Ballif BA, Elliott HL, Danuser G, Blenis J.

Mol Cell. 2011 Mar 18;41(6):661-71. doi: 10.1016/j.molcel.2011.02.031.


G-protein-coupled receptor-2-interacting protein-1 is required for endothelial cell directional migration and tumor angiogenesis via cortactin-dependent lamellipodia formation.

Majumder S, Sowden MP, Gerber SA, Thomas T, Christie CK, Mohan A, Yin G, Lord EM, Berk BC, Pang J.

Arterioscler Thromb Vasc Biol. 2014 Feb;34(2):419-26. doi: 10.1161/ATVBAHA.113.302689. Epub 2013 Nov 21.


Molecular requirements for actin-based lamella formation in Drosophila S2 cells.

Rogers SL, Wiedemann U, Stuurman N, Vale RD.

J Cell Biol. 2003 Sep 15;162(6):1079-88.


N-WASP, WAVE and Mena play different roles in the organization of actin cytoskeleton in lamellipodia.

Nakagawa H, Miki H, Ito M, Ohashi K, Takenawa T, Miyamoto S.

J Cell Sci. 2001 Apr;114(Pt 8):1555-65.


Ephrin-B ligands play a dual role in the control of neural crest cell migration.

Santiago A, Erickson CA.

Development. 2002 Aug;129(15):3621-32.


PtdIns(3,4,5)P3 binding is necessary for WAVE2-induced formation of lamellipodia.

Oikawa T, Yamaguchi H, Itoh T, Kato M, Ijuin T, Yamazaki D, Suetsugu S, Takenawa T.

Nat Cell Biol. 2004 May;6(5):420-6. Epub 2004 Apr 25.


Phosphorylation of WAVE2 by MAP kinases regulates persistent cell migration and polarity.

Danson CM, Pocha SM, Bloomberg GB, Cory GO.

J Cell Sci. 2007 Dec 1;120(Pt 23):4144-54.


Steering cell migration: lamellipodium dynamics and the regulation of directional persistence.

Krause M, Gautreau A.

Nat Rev Mol Cell Biol. 2014 Sep;15(9):577-90. doi: 10.1038/nrm3861. Review.


IRSp53/Eps8 complex is important for positive regulation of Rac and cancer cell motility/invasiveness.

Funato Y, Terabayashi T, Suenaga N, Seiki M, Takenawa T, Miki H.

Cancer Res. 2004 Aug 1;64(15):5237-44.

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