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Results: 1 to 20 of 141

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1.

Reversal of apixaban induced alterations in hemostasis by different coagulation factor concentrates: significance of studies in vitro with circulating human blood.

Escolar G, Fernandez-Gallego V, Arellano-Rodrigo E, Roquer J, Reverter JC, Sanz VV, Molina P, Lopez-Vilchez I, Diaz-Ricart M, Galan AM.

PLoS One. 2013 Nov 11;8(11):e78696. doi: 10.1371/journal.pone.0078696. eCollection 2013.

2.

Reversal of rivaroxaban-induced alterations on hemostasis by different coagulation factor concentrates – in vitro studies with steady and circulating human blood.

Escolar G, Arellano-Rodrigo E, Lopez-Vilchez I, Molina P, Sanchis J, Reverter JC, Carne X, Cid J, Villalta J, Tassies D, Galan AM, Diaz-Ricart M.

Circ J. 2015;79(2):331-8. doi: 10.1253/circj.CJ-14-0909. Epub 2014 Dec 8.

3.

Reversal of rivaroxaban-induced anticoagulation with prothrombin complex concentrate, activated prothrombin complex concentrate and recombinant activated factor VII in vitro.

Perzborn E, Heitmeier S, Laux V, Buchmüller A.

Thromb Res. 2014 Apr;133(4):671-81. doi: 10.1016/j.thromres.2014.01.017. Epub 2014 Jan 21.

4.
5.

Evaluation of recombinant activated factor VII, prothrombin complex concentrate, and fibrinogen concentrate to reverse apixaban in a rabbit model of bleeding and thrombosis.

Martin AC, Le Bonniec B, Fischer AM, Marchand-Leroux C, Gaussem P, Samama CM, Godier A.

Int J Cardiol. 2013 Oct 9;168(4):4228-33. doi: 10.1016/j.ijcard.2013.07.152. Epub 2013 Aug 6.

PMID:
23928345
6.

Impact of experimental haemodilution on platelet function, thrombin generation and clot firmness: effects of different coagulation factor concentrates.

Caballo C, Escolar G, Diaz-Ricart M, Lopez-Vílchez I, Lozano M, Cid J, Pino M, Beltrán J, Basora M, Pereira A, Galan AM.

Blood Transfus. 2013 Jul;11(3):391-9. doi: 10.2450/2012.0034-12. Epub 2012 Sep 19.

7.

Multimodal assessment of non-specific hemostatic agents for apixaban reversal.

Martin AC, Gouin-Thibault I, Siguret V, Mordohay A, Samama CM, Gaussem P, Le Bonniec B, Godier A.

J Thromb Haemost. 2015 Mar;13(3):426-36. doi: 10.1111/jth.12830. Epub 2015 Feb 5.

PMID:
25630710
8.

Tissue factor-mediated activation of the prothrombin complex concentrate (PCC) is differently inhibited by dabigatran, rivaroxaban, and apixaban: potential clinical implication.

Sadeghi N, Kahn D, Jeske W, Hoppensteadt D, Fareed J.

Clin Appl Thromb Hemost. 2013 Nov-Dec;19(6):589-99. doi: 10.1177/1076029613479819. Epub 2013 Mar 4.

PMID:
23463187
9.

Reversal of new, factor-specific oral anticoagulants by rFVIIa, prothrombin complex concentrate and activated prothrombin complex concentrate: a review of animal and human studies.

Lee FM, Chan AK, Lau KK, Chan HH.

Thromb Res. 2014 May;133(5):705-13. doi: 10.1016/j.thromres.2014.01.031. Epub 2014 Jan 31. Review.

PMID:
24666649
10.

Thrombin generation and fibrinolysis in anti-factor IX treated blood and plasma spiked with factor VIII inhibitor bypassing activity or recombinant factor VIIa.

Bolliger D, Szlam F, Molinaro RJ, Escobar MA, Levy JH, Tanaka KA.

Haemophilia. 2010 May;16(3):510-7. doi: 10.1111/j.1365-2516.2009.02164.x. Epub 2009 Dec 29. Erratum in: Haemophilia. 2010 May;16(3):567.

PMID:
20050927
11.

Apixaban, an oral, direct and highly selective factor Xa inhibitor: in vitro, antithrombotic and antihemostatic studies.

Wong PC, Crain EJ, Xin B, Wexler RR, Lam PY, Pinto DJ, Luettgen JM, Knabb RM.

J Thromb Haemost. 2008 May;6(5):820-9. doi: 10.1111/j.1538-7836.2008.02939.x. Epub 2008 Feb 25.

PMID:
18315548
12.

Effect of apixaban, an oral and direct factor Xa inhibitor, on coagulation activity biomarkers following acute coronary syndrome.

Becker RC, Alexander JH, Newby LK, Yang H, Barrett Y, Mohan P, Wang J, Harrington RA, Wallentin LC.

Thromb Haemost. 2010 Nov;104(5):976-83. doi: 10.1160/TH10-04-0247. Epub 2010 Aug 30.

PMID:
20806117
13.

Impact of apixaban on routine and specific coagulation assays: a practical laboratory guide.

Douxfils J, Chatelain C, Chatelain B, Dogné JM, Mullier F.

Thromb Haemost. 2013 Aug;110(2):283-94. doi: 10.1160/TH12-12-0898. Epub 2013 Jun 13.

PMID:
23765180
14.

In vitro effect of activated recombinant factor VII (rFVIIa) on coagulation properties of human blood at hypothermic temperatures.

Kheirabadi BS, Delgado AV, Dubick MA, Scherer MR, Fedyk CG, Holcomb JB, Pusateri AE.

J Trauma. 2007 Nov;63(5):1079-86.

PMID:
17993954
15.

In vitro effects of recombinant activated factor VII on thrombin generation and coagulation following inhibition of platelet procoagulant activity by prasugrel.

Mazzeffi M, Szlam F, Jakubowski JA, Tanaka KA, Sugidachi A, Levy JH.

Thromb Res. 2013 Jul;132(1):106-11. doi: 10.1016/j.thromres.2013.04.007. Epub 2013 May 9.

PMID:
23664633
16.

Clinical laboratory measurement of direct factor Xa inhibitors: anti-Xa assay is preferable to prothrombin time assay.

Barrett YC, Wang Z, Frost C, Shenker A.

Thromb Haemost. 2010 Dec;104(6):1263-71. doi: 10.1160/TH10-05-0328. Epub 2010 Oct 26.

PMID:
20978714
17.

Inhibitory effect of apixaban compared with rivaroxaban and dabigatran on thrombin generation assay.

Wong PC, White A, Luettgen J.

Hosp Pract (1995). 2013 Feb;41(1):19-25. doi: 10.3810/hp.2013.02.1009.

PMID:
23466964
18.

Evaluation of prothrombin complex concentrate and recombinant activated factor VII to reverse rivaroxaban in a rabbit model.

Godier A, Miclot A, Le Bonniec B, Durand M, Fischer AM, Emmerich J, Marchand-Leroux C, Lecompte T, Samama CM.

Anesthesiology. 2012 Jan;116(1):94-102. doi: 10.1097/ALN.0b013e318238c036.

PMID:
22042412
19.

Recombinant factor VIIa (Novoseven) restores deficient coagulation: experience from an ex vivo model.

Galán AM, Tonda R, Altisent C, Maragall S, Ordinas A, Escolar G.

Semin Hematol. 2001 Oct;38(4 Suppl 12):10-4.

PMID:
11735104
20.

Redistribution and hemostatic action of recombinant activated factor VII associated with platelets.

Lopez-Vilchez I, Hedner U, Altisent C, Diaz-Ricart M, Escolar G, Galan AM.

Am J Pathol. 2011 Jun;178(6):2938-48. doi: 10.1016/j.ajpath.2011.02.026.

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