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Results: 1 to 20 of 103

1.

Free fatty acids and protein kinase C activation induce GPR120 (free fatty acid receptor 4) phosphorylation.

Sánchez-Reyes OB, Romero-Ávila MT, Castillo-Badillo JA, Takei Y, Hirasawa A, Tsujimoto G, Villalobos-Molina R, García-Sáinz JA.

Eur J Pharmacol. 2014 Jan 15;723:368-74. doi: 10.1016/j.ejphar.2013.11.003. Epub 2013 Nov 12.

PMID:
24239485
[PubMed - in process]
2.

Agonism with the omega-3 fatty acids alpha-linolenic acid and docosahexaenoic acid mediates phosphorylation of both the short and long isoforms of the human GPR120 receptor.

Burns RN, Moniri NH.

Biochem Biophys Res Commun. 2010 Jun 11;396(4):1030-5. doi: 10.1016/j.bbrc.2010.05.057. Epub 2010 May 13.

PMID:
20471368
[PubMed - indexed for MEDLINE]
3.

Conventional protein kinase C isoforms mediate phorbol ester-induced lysophosphatidic acid LPA1 receptor phosphorylation.

Hernández-Méndez A, Alcántara-Hernández R, Acosta-Cervantes GC, Martínez-Ortiz J, Avendaño-Vázquez SE, García-Sáinz JA.

Eur J Pharmacol. 2014 Jan 15;723:124-30. doi: 10.1016/j.ejphar.2013.11.043. Epub 2013 Dec 16.

PMID:
24355769
[PubMed - in process]
4.

Omega-3 and omega-6 PUFAs induce the same GPR120-mediated signalling events, but with different kinetics and intensity in Caco-2 cells.

Mobraten K, Haug TM, Kleiveland CR, Lea T.

Lipids Health Dis. 2013 Jul 13;12:101. doi: 10.1186/1476-511X-12-101.

PMID:
23849180
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Mechanisms of homologous and heterologous phosphorylation of FFA receptor 4 (GPR120): GRK6 and PKC mediate phosphorylation of Thr³⁴⁷, Ser³⁵⁰, and Ser³⁵⁷ in the C-terminal tail.

Burns RN, Singh M, Senatorov IS, Moniri NH.

Biochem Pharmacol. 2014 Feb 15;87(4):650-9. doi: 10.1016/j.bcp.2013.12.016. Epub 2014 Jan 8.

PMID:
24412271
[PubMed - indexed for MEDLINE]
6.

P2Y(2) nucleotide receptor signaling in human monocytic cells: activation, desensitization and coupling to mitogen-activated protein kinases.

Santiago-Pérez LI, Flores RV, Santos-Berríos C, Chorna NE, Krugh B, Garrad RC, Erb L, Weisman GA, González FA.

J Cell Physiol. 2001 May;187(2):196-208.

PMID:
11267999
[PubMed - indexed for MEDLINE]
7.

Activation of the omega-3 fatty acid receptor GPR120 mediates anti-inflammatory actions in immortalized hypothalamic neurons.

Wellhauser L, Belsham DD.

J Neuroinflammation. 2014 Mar 27;11:60. doi: 10.1186/1742-2094-11-60.

PMID:
24674717
[PubMed - in process]
Free PMC Article
8.

Free fatty acids inhibit serum deprivation-induced apoptosis through GPR120 in a murine enteroendocrine cell line STC-1.

Katsuma S, Hatae N, Yano T, Ruike Y, Kimura M, Hirasawa A, Tsujimoto G.

J Biol Chem. 2005 May 20;280(20):19507-15. Epub 2005 Mar 17.

PMID:
15774482
[PubMed - indexed for MEDLINE]
Free Article
9.

Isoforms of protein kinase C involved in phorbol ester-induced sphingosine 1-phosphate receptor 1 phosphorylation and desensitization.

Morquecho-León MA, Bazúa-Valenti S, Romero-Ávila MT, García-Sáinz JA.

Biochim Biophys Acta. 2014 Feb;1843(2):327-34. doi: 10.1016/j.bbamcr.2013.11.002. Epub 2013 Nov 13.

PMID:
24239722
[PubMed - indexed for MEDLINE]
10.

Cloning and characterization of the rat free fatty acid receptor GPR120: in vivo effect of the natural ligand on GLP-1 secretion and proliferation of pancreatic beta cells.

Tanaka T, Yano T, Adachi T, Koshimizu TA, Hirasawa A, Tsujimoto G.

Naunyn Schmiedebergs Arch Pharmacol. 2008 Jun;377(4-6):515-22. doi: 10.1007/s00210-007-0250-y. Epub 2008 Mar 5.

PMID:
18320172
[PubMed - indexed for MEDLINE]
11.
12.

Investigation of free fatty acid associated recombinant membrane receptor protein expression in HEK293 cells using Raman spectroscopy, calcium imaging, and atomic force microscopy.

Lin J, Xu H, Wu Y, Tang M, McEwen GD, Liu P, Hansen DR, Gilbertson TA, Zhou A.

Anal Chem. 2013 Feb 5;85(3):1374-81. doi: 10.1021/ac3020577. Epub 2013 Jan 23.

PMID:
23234236
[PubMed - indexed for MEDLINE]
13.

Differential signaling by splice variants of the human free fatty acid receptor GPR120.

Watson SJ, Brown AJ, Holliday ND.

Mol Pharmacol. 2012 May;81(5):631-42. doi: 10.1124/mol.111.077388. Epub 2012 Jan 26.

PMID:
22282525
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Sensing of fatty acids for octanoylation of ghrelin involves a gustatory G-protein.

Janssen S, Laermans J, Iwakura H, Tack J, Depoortere I.

PLoS One. 2012;7(6):e40168. doi: 10.1371/journal.pone.0040168. Epub 2012 Jun 29.

PMID:
22768248
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Effect of retinoic acid on phorbol ester-stimulated differentiation and protein kinase C-dependent phosphorylation in the U937 human monoblastoid cell.

Ways DK, Dodd RC, Bennett TE, Hooker JL, Earp HS.

Cancer Res. 1988 Oct 15;48(20):5779-87.

PMID:
3048649
[PubMed - indexed for MEDLINE]
Free Article
16.

Cloning, expression, and pharmacological characterization of the GPR120 free fatty acid receptor from cynomolgus monkey: comparison with human GPR120 splice variants.

Moore K, Zhang Q, Murgolo N, Hosted T, Duffy R.

Comp Biochem Physiol B Biochem Mol Biol. 2009 Dec;154(4):419-26. doi: 10.1016/j.cbpb.2009.08.005. Epub 2009 Aug 31.

PMID:
19723586
[PubMed - indexed for MEDLINE]
17.

Protein tyrosine phosphorylation and p56lck modification in IL-2 or phorbol ester-activated human natural killer cells.

Einspahr KJ, Abraham RT, Dick CJ, Leibson PJ.

J Immunol. 1990 Sep 1;145(5):1490-7.

PMID:
1696599
[PubMed - indexed for MEDLINE]
18.

Novel selective ligands for free fatty acid receptors GPR120 and GPR40.

Hara T, Hirasawa A, Sun Q, Sadakane K, Itsubo C, Iga T, Adachi T, Koshimizu TA, Hashimoto T, Asakawa Y, Tsujimoto G.

Naunyn Schmiedebergs Arch Pharmacol. 2009 Sep;380(3):247-55. doi: 10.1007/s00210-009-0425-9. Epub 2009 May 27.

PMID:
19471906
[PubMed - indexed for MEDLINE]
19.

Thapsigargin-stimulated MAP kinase phosphorylation via CRAC channels and PLD activation: inhibitory action of docosahexaenoic acid.

Denys A, Aires V, Hichami A, Khan NA.

FEBS Lett. 2004 Apr 23;564(1-2):177-82.

PMID:
15094063
[PubMed - indexed for MEDLINE]
Free Article
20.

The pharmacology of TUG-891, a potent and selective agonist of the free fatty acid receptor 4 (FFA4/GPR120), demonstrates both potential opportunity and possible challenges to therapeutic agonism.

Hudson BD, Shimpukade B, Mackenzie AE, Butcher AJ, Pediani JD, Christiansen E, Heathcote H, Tobin AB, Ulven T, Milligan G.

Mol Pharmacol. 2013 Nov;84(5):710-25. doi: 10.1124/mol.113.087783. Epub 2013 Aug 26.

PMID:
23979972
[PubMed - indexed for MEDLINE]
Free PMC Article

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