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Protein S is a cofactor for platelet and endothelial tissue factor pathway inhibitor-α but not for cell surface-associated tissue factor pathway inhibitor.

Wood JP, Ellery PE, Maroney SA, Mast AE.

Arterioscler Thromb Vasc Biol. 2014 Jan;34(1):169-76. doi: 10.1161/ATVBAHA.113.302655. Epub 2013 Nov 14.


Biology of tissue factor pathway inhibitor.

Wood JP, Ellery PE, Maroney SA, Mast AE.

Blood. 2014 May 8;123(19):2934-43. doi: 10.1182/blood-2013-11-512764. Epub 2014 Mar 11. Review.


TFPIα and TFPIβ are expressed at the surface of breast cancer cells and inhibit TF-FVIIa activity.

Stavik B, Tinholt M, Sletten M, Skretting G, Sandset PM, Iversen N.

J Hematol Oncol. 2013 Jan 15;6:5. doi: 10.1186/1756-8722-6-5.


Tissue factor pathway inhibitor-alpha inhibits prothrombinase during the initiation of blood coagulation.

Wood JP, Bunce MW, Maroney SA, Tracy PB, Camire RM, Mast AE.

Proc Natl Acad Sci U S A. 2013 Oct 29;110(44):17838-43. doi: 10.1073/pnas.1310444110. Epub 2013 Oct 14.


TFPIβ is the GPI-anchored TFPI isoform on human endothelial cells and placental microsomes.

Girard TJ, Tuley E, Broze GJ Jr.

Blood. 2012 Feb 2;119(5):1256-62. doi: 10.1182/blood-2011-10-388512. Epub 2011 Dec 5.


Caveolae optimize tissue factor-Factor VIIa inhibitory activity of cell-surface-associated tissue factor pathway inhibitor.

Maroney SA, Ellery PE, Wood JP, Ferrel JP, Bonesho CE, Mast AE.

Biochem J. 2012 Apr 1;443(1):259-66. doi: 10.1042/BJ20111994.


Platelet protein S directly inhibits procoagulant activity on platelets and microparticles.

Stavenuiter F, Davis NF, Duan E, Gale AJ, Heeb MJ.

Thromb Haemost. 2013 Feb;109(2):229-37. doi: 10.1160/TH12-08-0622. Epub 2012 Dec 13.


Comparison of the inhibitory activities of human tissue factor pathway inhibitor (TFPI)α and TFPIβ.

Maroney SA, Ellery PE, Wood JP, Ferrel JP, Martinez ND, Mast AE.

J Thromb Haemost. 2013 May;11(5):911-8. doi: 10.1111/jth.12188.


Translation of human tissue factor pathway inhibitor-β mRNA is controlled by alternative splicing within the 5' untranslated region.

Ellery PE, Maroney SA, Martinez ND, Wickens MP, Mast AE.

Arterioscler Thromb Vasc Biol. 2014 Jan;34(1):187-95. doi: 10.1161/ATVBAHA.113.302660. Epub 2013 Nov 14.


Tissue factor pathway inhibitor: structure-function.

Broze GJ Jr, Girard TJ.

Front Biosci (Landmark Ed). 2012 Jan 1;17:262-80. Review.


Glycosyl phosphatidylinositol anchorage of tissue factor pathway inhibitor.

Zhang J, Piro O, Lu L, Broze GJ Jr.

Circulation. 2003 Aug 5;108(5):623-7. Epub 2003 Jun 30.


Cellular expression and biological activities of alternatively spliced forms of tissue factor pathway inhibitor.

Maroney SA, Hansen KG, Mast AE.

Curr Opin Hematol. 2013 Sep;20(5):403-9. doi: 10.1097/MOH.0b013e3283634412. Review.


Inhibitory effects of LDL-associated tissue factor pathway inhibitor.

Augustsson C, Hilden I, Petersen LC.

Thromb Res. 2014 Jul;134(1):132-7. doi: 10.1016/j.thromres.2014.03.043. Epub 2014 Apr 1.


Protein S is a cofactor for tissue factor pathway inhibitor.

Rosing J, Maurissen LF, Tchaikovski SN, Tans G, Hackeng TM.

Thromb Res. 2008;122 Suppl 1:S60-3. doi: 10.1016/S0049-3848(08)70021-5. Review.


Tissue factor pathway inhibitor-gamma is an active alternatively spliced form of tissue factor pathway inhibitor present in mice but not in humans.

Maroney SA, Ferrel JP, Collins ML, Mast AE.

J Thromb Haemost. 2008 Aug;6(8):1344-51. doi: 10.1111/j.1538-7836.2008.03033.x. Epub 2008 May 22.


Inhibition of tissue factor:factor VIIa-catalyzed factor IX and factor X activation by TFPI and TFPI constructs.

Peraramelli S, Thomassen S, Heinzmann A, Rosing J, Hackeng TM, Hartmann R, Scheiflinger F, Dockal M.

J Thromb Haemost. 2014 Nov;12(11):1826-37. doi: 10.1111/jth.12713. Epub 2014 Oct 12.


Tissue factor-independent inhibition of thrombin generation by tissue factor pathway inhibitor-α.

Thomassen MC, Heinzmann AC, Herfs L, Hartmann R, Dockal M, Scheiflinger F, Hackeng TM, Rosing J.

J Thromb Haemost. 2015 Jan;13(1):92-100. doi: 10.1111/jth.12766. Epub 2014 Nov 29.


The Kunitz-3 domain of TFPI-alpha is required for protein S-dependent enhancement of factor Xa inhibition.

Ndonwi M, Tuley EA, Broze GJ Jr.

Blood. 2010 Aug 26;116(8):1344-51. doi: 10.1182/blood-2009-10-246686. Epub 2010 May 17.


Factor Xa dimerization competes with prothrombinase complex formation on platelet-like membrane surfaces.

Koklic T, Chattopadhyay R, Majumder R, Lentz BR.

Biochem J. 2015 Apr 1;467(1):37-46. doi: 10.1042/BJ20141177.

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