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Results: 1 to 20 of 104

1.

SUMO-1 gene transfer improves cardiac function in a large-animal model of heart failure.

Tilemann L, Lee A, Ishikawa K, Aguero J, Rapti K, Santos-Gallego C, Kohlbrenner E, Fish KM, Kho C, Hajjar RJ.

Sci Transl Med. 2013 Nov 13;5(211):211ra159. doi: 10.1126/scitranslmed.3006487.

PMID:
24225946
[PubMed - indexed for MEDLINE]
2.

Reversal of cardiac dysfunction after long-term expression of SERCA2a by gene transfer in a pre-clinical model of heart failure.

Kawase Y, Ly HQ, Prunier F, Lebeche D, Shi Y, Jin H, Hadri L, Yoneyama R, Hoshino K, Takewa Y, Sakata S, Peluso R, Zsebo K, Gwathmey JK, Tardif JC, Tanguay JF, Hajjar RJ.

J Am Coll Cardiol. 2008 Mar 18;51(11):1112-9. doi: 10.1016/j.jacc.2007.12.014.

PMID:
18342232
[PubMed - indexed for MEDLINE]
Free Article
3.

[Effects of sarcoplasmic reticulum Ca(2+)-ATPase gene transfer in a minipig model of chronic ischemic heart failure].

Xin W, Lu XC, Li XY, Niu K, Cai JM.

Zhonghua Xin Xue Guan Bing Za Zhi. 2011 Apr;39(4):336-42. doi: 10.3760/cma.j.issn.0253-3758.2011.04.012. Chinese.

PMID:
21624310
[PubMed - indexed for MEDLINE]
4.

[Adeno-associated viral gene transfer of SERCA2a improves heart function in chronic congestive heart failure rats].

Hui HP, Li XY, Liu XH, Sun S, Lu XC, Liu T, Yang W.

Zhonghua Xin Xue Guan Bing Za Zhi. 2006 Apr;34(4):357-62. Chinese.

PMID:
16776934
[PubMed - indexed for MEDLINE]
5.

Improvement in cardiac function after sarcoplasmic reticulum Ca2+-ATPase gene transfer in a beagle heart failure model.

Mi YF, Li XY, Tang LJ, Lu XC, Fu ZQ, Ye WH.

Chin Med J (Engl). 2009 Jun 20;122(12):1423-8.

PMID:
19567165
[PubMed - indexed for MEDLINE]
Free Article
6.

[Overexpression of sarcoplasmic reticulum calcium ATPase induced hemodynamic and proteomic changes in a dog model of heart failure].

Fu ZQ, Li XY, Liu XH, Sun S, Liu T, Mi YF, Zhou SA, Ye WH, Wang QS.

Zhonghua Xin Xue Guan Bing Za Zhi. 2008 Mar;36(3):260-5. Chinese.

PMID:
19099986
[PubMed - indexed for MEDLINE]
7.

Targeted sarcoplasmic reticulum Ca2+ ATPase 2a gene delivery to restore electrical stability in the failing heart.

Cutler MJ, Wan X, Plummer BN, Liu H, Deschenes I, Laurita KR, Hajjar RJ, Rosenbaum DS.

Circulation. 2012 Oct 23;126(17):2095-104. doi: 10.1161/CIRCULATIONAHA.111.071480. Epub 2012 Sep 27.

PMID:
23019291
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

SUMO1-dependent modulation of SERCA2a in heart failure.

Kho C, Lee A, Jeong D, Oh JG, Chaanine AH, Kizana E, Park WJ, Hajjar RJ.

Nature. 2011 Sep 7;477(7366):601-5. doi: 10.1038/nature10407.

PMID:
21900893
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Improvement in survival and cardiac metabolism after gene transfer of sarcoplasmic reticulum Ca(2+)-ATPase in a rat model of heart failure.

del Monte F, Williams E, Lebeche D, Schmidt U, Rosenzweig A, Gwathmey JK, Lewandowski ED, Hajjar RJ.

Circulation. 2001 Sep 18;104(12):1424-9.

PMID:
11560860
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Adenoviral gene transfer of SERCA2a improves left-ventricular function in aortic-banded rats in transition to heart failure.

Miyamoto MI, del Monte F, Schmidt U, DiSalvo TS, Kang ZB, Matsui T, Guerrero JL, Gwathmey JK, Rosenzweig A, Hajjar RJ.

Proc Natl Acad Sci U S A. 2000 Jan 18;97(2):793-8.

PMID:
10639159
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Concomitant intravenous nitroglycerin with intracoronary delivery of AAV1.SERCA2a enhances gene transfer in porcine hearts.

Karakikes I, Hadri L, Rapti K, Ladage D, Ishikawa K, Tilemann L, Yi GH, Morel C, Gwathmey JK, Zsebo K, Weber T, Kawase Y, Hajjar RJ.

Mol Ther. 2012 Mar;20(3):565-71. doi: 10.1038/mt.2011.268. Epub 2012 Jan 3.

PMID:
22215018
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

AAV9.I-1c delivered via direct coronary infusion in a porcine model of heart failure improves contractility and mitigates adverse remodeling.

Fish KM, Ladage D, Kawase Y, Karakikes I, Jeong D, Ly H, Ishikawa K, Hadri L, Tilemann L, Muller-Ehmsen J, Samulski RJ, Kranias EG, Hajjar RJ.

Circ Heart Fail. 2013 Mar;6(2):310-7. doi: 10.1161/CIRCHEARTFAILURE.112.971325. Epub 2012 Dec 27.

PMID:
23271792
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Augmentation of left ventricular mechanics by recirculation-mediated AAV2/1-SERCA2a gene delivery in experimental heart failure.

Mariani JA, Smolic A, Preovolos A, Byrne MJ, Power JM, Kaye DM.

Eur J Heart Fail. 2011 Mar;13(3):247-53. doi: 10.1093/eurjhf/hfq234. Epub 2011 Feb 2.

PMID:
21289077
[PubMed - indexed for MEDLINE]
14.

Gene delivery of sarcoplasmic reticulum calcium ATPase inhibits ventricular remodeling in ischemic mitral regurgitation.

Beeri R, Chaput M, Guerrero JL, Kawase Y, Yosefy C, Abedat S, Karakikes I, Morel C, Tisosky A, Sullivan S, Handschumacher MD, Gilon D, Vlahakes GJ, Hajjar RJ, Levine RA.

Circ Heart Fail. 2010 Sep;3(5):627-34. doi: 10.1161/CIRCHEARTFAILURE.109.891184. Epub 2010 Jul 15.

PMID:
20634484
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

[Treatment of chronic heart failure by overexpressing sarcoplasmic reticulum calcium ATPase through gene therapy: an experiment with rats].

Li XY, Hui HP, Lu XC, Guo YT.

Zhonghua Yi Xue Za Zhi. 2006 May 9;86(17):1174-8. Chinese.

PMID:
16796857
[PubMed - indexed for MEDLINE]
16.

Long-term effects of AAV1/SERCA2a gene transfer in patients with severe heart failure: analysis of recurrent cardiovascular events and mortality.

Zsebo K, Yaroshinsky A, Rudy JJ, Wagner K, Greenberg B, Jessup M, Hajjar RJ.

Circ Res. 2014 Jan 3;114(1):101-8. doi: 10.1161/CIRCRESAHA.113.302421. Epub 2013 Sep 24.

PMID:
24065463
[PubMed - indexed for MEDLINE]
17.

SERCA2a gene transfer enhances eNOS expression and activity in endothelial cells.

Hadri L, Bobe R, Kawase Y, Ladage D, Ishikawa K, Atassi F, Lebeche D, Kranias EG, Leopold JA, Lompré AM, Lipskaia L, Hajjar RJ.

Mol Ther. 2010 Jul;18(7):1284-92. doi: 10.1038/mt.2010.77. Epub 2010 May 11.

PMID:
20461063
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Recirculating cardiac delivery of AAV2/1SERCA2a improves myocardial function in an experimental model of heart failure in large animals.

Byrne MJ, Power JM, Preovolos A, Mariani JA, Hajjar RJ, Kaye DM.

Gene Ther. 2008 Dec;15(23):1550-7. doi: 10.1038/gt.2008.120. Epub 2008 Jul 24.

PMID:
18650850
[PubMed - indexed for MEDLINE]
19.

Cardiac AAV9-S100A1 gene therapy rescues post-ischemic heart failure in a preclinical large animal model.

Pleger ST, Shan C, Ksienzyk J, Bekeredjian R, Boekstegers P, Hinkel R, Schinkel S, Leuchs B, Ludwig J, Qiu G, Weber C, Raake P, Koch WJ, Katus HA, Müller OJ, Most P.

Sci Transl Med. 2011 Jul 20;3(92):92ra64. doi: 10.1126/scitranslmed.3002097.

PMID:
21775667
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Design of a phase 1/2 trial of intracoronary administration of AAV1/SERCA2a in patients with heart failure.

Hajjar RJ, Zsebo K, Deckelbaum L, Thompson C, Rudy J, Yaroshinsky A, Ly H, Kawase Y, Wagner K, Borow K, Jaski B, London B, Greenberg B, Pauly DF, Patten R, Starling R, Mancini D, Jessup M.

J Card Fail. 2008 Jun;14(5):355-67. doi: 10.1016/j.cardfail.2008.02.005. Epub 2008 May 27.

PMID:
18514926
[PubMed - indexed for MEDLINE]

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