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Results: 1 to 20 of 88

1.

Aβ-induced microglial cell activation is inhibited by baicalin through the JAK2/STAT3 signaling pathway.

Xiong J, Wang C, Chen H, Hu Y, Tian L, Pan J, Geng M.

Int J Neurosci. 2014 Aug;124(8):609-20. doi: 10.3109/00207454.2013.865027. Epub 2013 Dec 12.

PMID:
24219385
[PubMed - in process]
2.

The role of the JAK2-STAT3 pathway in pro-inflammatory responses of EMF-stimulated N9 microglial cells.

Yang X, He G, Hao Y, Chen C, Li M, Wang Y, Zhang G, Yu Z.

J Neuroinflammation. 2010 Sep 9;7:54. doi: 10.1186/1742-2094-7-54.

PMID:
20828402
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

VIP enhances phagocytosis of fibrillar beta-amyloid by microglia and attenuates amyloid deposition in the brain of APP/PS1 mice.

Song M, Xiong JX, Wang YY, Tang J, Zhang B, Bai Y.

PLoS One. 2012;7(2):e29790. doi: 10.1371/journal.pone.0029790. Epub 2012 Feb 6.

PMID:
22328918
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

CD45RB is a novel molecular therapeutic target to inhibit Abeta peptide-induced microglial MAPK activation.

Zhu Y, Hou H, Nikolic WV, Ehrhart J, Rrapo E, Bickford P, Giunta B, Tan J.

PLoS One. 2008 May 14;3(5):e2135. doi: 10.1371/journal.pone.0002135.

PMID:
18478117
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

The synthetic triterpenoid CDDO-methyl ester modulates microglial activities, inhibits TNF production, and provides dopaminergic neuroprotection.

Tran TA, McCoy MK, Sporn MB, Tansey MG.

J Neuroinflammation. 2008 May 12;5:14. doi: 10.1186/1742-2094-5-14.

PMID:
18474101
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Baicalin attenuates proinflammatory cytokine production in oxygen-glucose deprived challenged rat microglial cells by inhibiting TLR4 signaling pathway.

Hou J, Wang J, Zhang P, Li D, Zhang C, Zhao H, Fu J, Wang B, Liu J.

Int Immunopharmacol. 2012 Dec;14(4):749-57. doi: 10.1016/j.intimp.2012.10.013. Epub 2012 Oct 29.

PMID:
23116637
[PubMed - indexed for MEDLINE]
7.

Hydroxy-safflor yellow A inhibits neuroinflammation mediated by Aβ₁₋₄₂ in BV-2 cells.

Zhang Z, Wu Z, Zhu X, Hui X, Pan J, Xu Y.

Neurosci Lett. 2014 Mar 6;562:39-44. doi: 10.1016/j.neulet.2014.01.005. Epub 2014 Jan 9.

PMID:
24412680
[PubMed - in process]
8.

Amyloid-β induces hepatic insulin resistance in vivo via JAK2.

Zhang Y, Zhou B, Deng B, Zhang F, Wu J, Wang Y, Le Y, Zhai Q.

Diabetes. 2013 Apr;62(4):1159-66. doi: 10.2337/db12-0670. Epub 2012 Dec 6.

PMID:
23223021
[PubMed - indexed for MEDLINE]
Free PMC Article
9.
10.

CD45 opposes beta-amyloid peptide-induced microglial activation via inhibition of p44/42 mitogen-activated protein kinase.

Tan J, Town T, Mori T, Wu Y, Saxe M, Crawford F, Mullan M.

J Neurosci. 2000 Oct 15;20(20):7587-94.

PMID:
11027218
[PubMed - indexed for MEDLINE]
Free Article
11.

Inhibition of Src kinase activity attenuates amyloid associated microgliosis in a murine model of Alzheimer's disease.

Dhawan G, Combs CK.

J Neuroinflammation. 2012 Jul 2;9:117. doi: 10.1186/1742-2094-9-117.

PMID:
22673542
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

TLR4 mutation reduces microglial activation, increases Aβ deposits and exacerbates cognitive deficits in a mouse model of Alzheimer's disease.

Song M, Jin J, Lim JE, Kou J, Pattanayak A, Rehman JA, Kim HD, Tahara K, Lalonde R, Fukuchi K.

J Neuroinflammation. 2011 Aug 9;8:92. doi: 10.1186/1742-2094-8-92.

PMID:
21827663
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Signaling through JAK2-STAT5 pathway is essential for IL-3-induced activation of microglia.

Natarajan C, Sriram S, Muthian G, Bright JJ.

Glia. 2004 Jan 15;45(2):188-96. Erratum in: Glia. 2004 Sep;47(4):387.

PMID:
14730712
[PubMed - indexed for MEDLINE]
14.

Sinomenine inhibits microglial activation by Aβ and confers neuroprotection.

Shukla SM, Sharma SK.

J Neuroinflammation. 2011 Sep 14;8:117. doi: 10.1186/1742-2094-8-117.

PMID:
21917137
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Tetrandrine suppresses amyloid-β-induced inflammatory cytokines by inhibiting NF-κB pathway in murine BV2 microglial cells.

He FQ, Qiu BY, Li TK, Xie Q, Cui de J, Huang XL, Gan HT.

Int Immunopharmacol. 2011 Sep;11(9):1220-5. doi: 10.1016/j.intimp.2011.03.023. Epub 2011 Apr 13.

PMID:
21496499
[PubMed - indexed for MEDLINE]
16.

Geniposide attenuates oligomeric Aβ(1-42)-induced inflammatory response by targeting RAGE-dependent signaling in BV2 cells.

Lv C, Wang L, Liu X, Cong X, Yan SS, Wang Y, Zhang W.

Curr Alzheimer Res. 2014;11(5):430-40.

PMID:
24801214
[PubMed - in process]
17.

TGF-beta1 blockade of microglial chemotaxis toward Abeta aggregates involves SMAD signaling and down-regulation of CCL5.

Huang WC, Yen FC, Shie FS, Pan CM, Shiao YJ, Yang CN, Huang FL, Sung YJ, Tsay HJ.

J Neuroinflammation. 2010 Apr 29;7:28. doi: 10.1186/1742-2094-7-28.

PMID:
20429874
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Tyk2/STAT3 signaling mediates beta-amyloid-induced neuronal cell death: implications in Alzheimer's disease.

Wan J, Fu AK, Ip FC, Ng HK, Hugon J, Page G, Wang JH, Lai KO, Wu Z, Ip NY.

J Neurosci. 2010 May 19;30(20):6873-81. doi: 10.1523/JNEUROSCI.0519-10.2010.

PMID:
20484629
[PubMed - indexed for MEDLINE]
Free Article
19.

Surfactin exhibits neuroprotective effects by inhibiting amyloid β-mediated microglial activation.

Park SY, Kim JH, Lee SJ, Kim Y.

Neurotoxicology. 2013 Sep;38:115-23. doi: 10.1016/j.neuro.2013.07.004. Epub 2013 Jul 29.

PMID:
23906708
[PubMed - in process]
20.

Neutralization of granulocyte macrophage colony-stimulating factor decreases amyloid beta 1-42 and suppresses microglial activity in a transgenic mouse model of Alzheimer's disease.

Manczak M, Mao P, Nakamura K, Bebbington C, Park B, Reddy PH.

Hum Mol Genet. 2009 Oct 15;18(20):3876-93. doi: 10.1093/hmg/ddp331. Epub 2009 Jul 19.

PMID:
19617638
[PubMed - indexed for MEDLINE]
Free PMC Article

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