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Results: 1 to 20 of 99

1.

Different dynamic movements of wild-type and pathogenic VCPs and their cofactors to damaged mitochondria in a Parkin-mediated mitochondrial quality control system.

Kimura Y, Fukushi J, Hori S, Matsuda N, Okatsu K, Kakiyama Y, Kawawaki J, Kakizuka A, Tanaka K.

Genes Cells. 2013 Dec;18(12):1131-43. doi: 10.1111/gtc.12103. Epub 2013 Nov 12.

PMID:
24215292
[PubMed - in process]
2.

Rescue of growth defects of yeast cdc48 mutants by pathogenic IBMPFD-VCPs.

Takata T, Kimura Y, Ohnuma Y, Kawawaki J, Kakiyama Y, Tanaka K, Kakizuka A.

J Struct Biol. 2012 Aug;179(2):93-103. doi: 10.1016/j.jsb.2012.06.005. Epub 2012 Jun 19.

PMID:
22728077
[PubMed - indexed for MEDLINE]
Free Article
3.

VCP is essential for mitochondrial quality control by PINK1/Parkin and this function is impaired by VCP mutations.

Kim NC, Tresse E, Kolaitis RM, Molliex A, Thomas RE, Alami NH, Wang B, Joshi A, Smith RB, Ritson GP, Winborn BJ, Moore J, Lee JY, Yao TP, Pallanck L, Kundu M, Taylor JP.

Neuron. 2013 Apr 10;78(1):65-80. doi: 10.1016/j.neuron.2013.02.029. Epub 2013 Mar 14. Erratum in: Neuron. 2013 Apr 24;78(2):403.

PMID:
23498974
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

A unique IBMPFD-related P97/VCP mutation with differential binding pattern and subcellular localization.

Erzurumlu Y, Kose FA, Gozen O, Gozuacik D, Toth EA, Ballar P.

Int J Biochem Cell Biol. 2013 Apr;45(4):773-82. doi: 10.1016/j.biocel.2013.01.006. Epub 2013 Jan 16.

PMID:
23333620
[PubMed - indexed for MEDLINE]
5.

Inclusion body myopathy-associated mutations in p97/VCP impair endoplasmic reticulum-associated degradation.

Weihl CC, Dalal S, Pestronk A, Hanson PI.

Hum Mol Genet. 2006 Jan 15;15(2):189-99. Epub 2005 Dec 1.

PMID:
16321991
[PubMed - indexed for MEDLINE]
Free Article
6.

The AAA ATPase p97/VCP interacts with its alternative co-factors, Ufd1-Npl4 and p47, through a common bipartite binding mechanism.

Bruderer RM, Brasseur C, Meyer HH.

J Biol Chem. 2004 Nov 26;279(48):49609-16. Epub 2004 Sep 15.

PMID:
15371428
[PubMed - indexed for MEDLINE]
Free Article
7.

Pathogenic VCP mutations induce mitochondrial uncoupling and reduced ATP levels.

Bartolome F, Wu HC, Burchell VS, Preza E, Wray S, Mahoney CJ, Fox NC, Calvo A, Canosa A, Moglia C, Mandrioli J, Chiò A, Orrell RW, Houlden H, Hardy J, Abramov AY, Plun-Favreau H.

Neuron. 2013 Apr 10;78(1):57-64. doi: 10.1016/j.neuron.2013.02.028. Epub 2013 Mar 14.

PMID:
23498975
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Pathogenic VCP/TER94 alleles are dominant actives and contribute to neurodegeneration by altering cellular ATP level in a Drosophila IBMPFD model.

Chang YC, Hung WT, Chang YC, Chang HC, Wu CL, Chiang AS, Jackson GR, Sang TK.

PLoS Genet. 2011 Feb 3;7(2):e1001288. doi: 10.1371/journal.pgen.1001288.

PMID:
21304887
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Structural insights into the p97-Ufd1-Npl4 complex.

Pye VE, Beuron F, Keetch CA, McKeown C, Robinson CV, Meyer HH, Zhang X, Freemont PS.

Proc Natl Acad Sci U S A. 2007 Jan 9;104(2):467-72. Epub 2007 Jan 3.

PMID:
17202270
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Roles of VCP in human neurodegenerative disorders.

Kakizuka A.

Biochem Soc Trans. 2008 Feb;36(Pt 1):105-8. doi: 10.1042/BST0360105. Review.

PMID:
18208395
[PubMed - indexed for MEDLINE]
11.

Inclusion body myopathy, Paget's disease of the bone and fronto-temporal dementia: a disorder of autophagy.

Ju JS, Weihl CC.

Hum Mol Genet. 2010 Apr 15;19(R1):R38-45. doi: 10.1093/hmg/ddq157. Epub 2010 Apr 21. Review.

PMID:
20410287
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Transgenic expression of inclusion body myopathy associated mutant p97/VCP causes weakness and ubiquitinated protein inclusions in mice.

Weihl CC, Miller SE, Hanson PI, Pestronk A.

Hum Mol Genet. 2007 Apr 15;16(8):919-28. Epub 2007 Feb 28.

PMID:
17329348
[PubMed - indexed for MEDLINE]
Free Article
13.

TDP-43 mediates degeneration in a novel Drosophila model of disease caused by mutations in VCP/p97.

Ritson GP, Custer SK, Freibaum BD, Guinto JB, Geffel D, Moore J, Tang W, Winton MJ, Neumann M, Trojanowski JQ, Lee VM, Forman MS, Taylor JP.

J Neurosci. 2010 Jun 2;30(22):7729-39. doi: 10.1523/JNEUROSCI.5894-09.2010.

PMID:
20519548
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

ATP binding to p97/VCP D1 domain regulates selective recruitment of adaptors to its proximal N-domain.

Chia WS, Chia DX, Rao F, Bar Nun S, Geifman Shochat S.

PLoS One. 2012;7(12):e50490. doi: 10.1371/journal.pone.0050490. Epub 2012 Dec 3.

PMID:
23226521
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Create and preserve: proteostasis in development and aging is governed by Cdc48/p97/VCP.

Franz A, Ackermann L, Hoppe T.

Biochim Biophys Acta. 2014 Jan;1843(1):205-15. doi: 10.1016/j.bbamcr.2013.03.031. Epub 2013 Apr 10. Review.

PMID:
23583830
[PubMed - indexed for MEDLINE]
16.

Transgenic mice expressing mutant forms VCP/p97 recapitulate the full spectrum of IBMPFD including degeneration in muscle, brain and bone.

Custer SK, Neumann M, Lu H, Wright AC, Taylor JP.

Hum Mol Genet. 2010 May 1;19(9):1741-55. doi: 10.1093/hmg/ddq050. Epub 2010 Feb 10.

PMID:
20147319
[PubMed - indexed for MEDLINE]
Free Article
17.

The multiple faces of valosin-containing protein-associated diseases: inclusion body myopathy with Paget's disease of bone, frontotemporal dementia, and amyotrophic lateral sclerosis.

Nalbandian A, Donkervoort S, Dec E, Badadani M, Katheria V, Rana P, Nguyen C, Mukherjee J, Caiozzo V, Martin B, Watts GD, Vesa J, Smith C, Kimonis VE.

J Mol Neurosci. 2011 Nov;45(3):522-31. doi: 10.1007/s12031-011-9627-y. Epub 2011 Sep 3. Review.

PMID:
21892620
[PubMed - indexed for MEDLINE]
18.

The homozygote VCP(R¹⁵⁵H/R¹⁵⁵H) mouse model exhibits accelerated human VCP-associated disease pathology.

Nalbandian A, Llewellyn KJ, Kitazawa M, Yin HZ, Badadani M, Khanlou N, Edwards R, Nguyen C, Mukherjee J, Mozaffar T, Watts G, Weiss J, Kimonis VE.

PLoS One. 2012;7(9):e46308. doi: 10.1371/journal.pone.0046308. Epub 2012 Sep 28.

PMID:
23029473
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

VCP/p97 is essential for maturation of ubiquitin-containing autophagosomes and this function is impaired by mutations that cause IBMPFD.

Tresse E, Salomons FA, Vesa J, Bott LC, Kimonis V, Yao TP, Dantuma NP, Taylor JP.

Autophagy. 2010 Feb;6(2):217-27. Epub 2010 Feb 22.

PMID:
20104022
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Recent advances in p97/VCP/Cdc48 cellular functions.

Yamanaka K, Sasagawa Y, Ogura T.

Biochim Biophys Acta. 2012 Jan;1823(1):130-7. doi: 10.1016/j.bbamcr.2011.07.001. Epub 2011 Jul 12. Review.

PMID:
21781992
[PubMed - indexed for MEDLINE]
Free Article

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