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Results: 1 to 20 of 101

Similar articles for PubMed (Select 24214142)

1.

Inhibition of Niemann-Pick-type C1-like1 by ezetimibe activates autophagy in human hepatocytes and reduces mutant α1-antitrypsin Z deposition.

Yamamura T, Ohsaki Y, Suzuki M, Shinohara Y, Tatematsu T, Cheng J, Okada M, Ohmiya N, Hirooka Y, Goto H, Fujimoto T.

Hepatology. 2014 Apr;59(4):1591-9. doi: 10.1002/hep.26930. Epub 2014 Feb 28.

PMID:
24214142
2.

Ezetimibe restores biliary cholesterol excretion in mice expressing Niemann-Pick C1-Like 1 only in liver.

Tang W, Jia L, Ma Y, Xie P, Haywood J, Dawson PA, Li J, Yu L.

Biochim Biophys Acta. 2011 Sep;1811(9):549-55. doi: 10.1016/j.bbalip.2011.05.013. Epub 2011 Jun 12.

3.

In vivo responsiveness to ezetimibe correlates with niemann-pick C1 like-1 (NPC1L1) binding affinity: Comparison of multiple species NPC1L1 orthologs.

Hawes BE, O'neill KA, Yao X, Crona JH, Davis HR Jr, Graziano MP, Altmann SW.

Mol Pharmacol. 2007 Jan;71(1):19-29. Epub 2006 Sep 27.

4.

Niemann-Pick C1-Like 1 and cholesterol uptake.

Wang LJ, Song BL.

Biochim Biophys Acta. 2012 Jul;1821(7):964-72. doi: 10.1016/j.bbalip.2012.03.004. Epub 2012 Mar 28. Review.

PMID:
22480541
5.

Hepatic Niemann-Pick C1-like 1 regulates biliary cholesterol concentration and is a target of ezetimibe.

Temel RE, Tang W, Ma Y, Rudel LL, Willingham MC, Ioannou YA, Davies JP, Nilsson LM, Yu L.

J Clin Invest. 2007 Jul;117(7):1968-78.

6.

The cholesterol absorption inhibitor ezetimibe acts by blocking the sterol-induced internalization of NPC1L1.

Ge L, Wang J, Qi W, Miao HH, Cao J, Qu YX, Li BL, Song BL.

Cell Metab. 2008 Jun;7(6):508-19. doi: 10.1016/j.cmet.2008.04.001.

7.
8.
9.

Niemann-pick C1-like 1 mediates alpha-tocopherol transport.

Narushima K, Takada T, Yamanashi Y, Suzuki H.

Mol Pharmacol. 2008 Jul;74(1):42-9. doi: 10.1124/mol.107.043034. Epub 2008 Apr 10.

10.

Ezetimibe blocks the internalization of NPC1L1 and cholesterol in mouse small intestine.

Xie C, Zhou ZS, Li N, Bian Y, Wang YJ, Wang LJ, Li BL, Song BL.

J Lipid Res. 2012 Oct;53(10):2092-101. Epub 2012 Jul 17.

11.

Niemann-pick C1-like 1 (NPC1L1) protein in intestinal and hepatic cholesterol transport.

Jia L, Betters JL, Yu L.

Annu Rev Physiol. 2011;73:239-59. doi: 10.1146/annurev-physiol-012110-142233. Review.

12.

Ezetimibe, a selective inhibitor of the transport of cholesterol.

Miura S, Saku K.

Intern Med. 2008;47(13):1165-70. Epub 2008 Jul 1. Review.

13.

The Niemann-Pick C1 like 1 (NPC1L1) inhibitor ezetimibe improves metabolic disease via decreased liver X receptor (LXR) activity in liver of obese male mice.

Sugizaki T, Watanabe M, Horai Y, Kaneko-Iwasaki N, Arita E, Miyazaki T, Morimoto K, Honda A, Irie J, Itoh H.

Endocrinology. 2014 Aug;155(8):2810-9. doi: 10.1210/en.2013-2143. Epub 2014 Apr 28.

PMID:
24773344
14.

Ezetimibe inhibits hepatic Niemann-Pick C1-Like 1 to facilitate macrophage reverse cholesterol transport in mice.

Xie P, Jia L, Ma Y, Ou J, Miao H, Wang N, Guo F, Yazdanyar A, Jiang XC, Yu L.

Arterioscler Thromb Vasc Biol. 2013 May;33(5):920-5. doi: 10.1161/ATVBAHA.112.301187. Epub 2013 Mar 7.

15.

Ezetimibe blocks internalization of the NPC1L1/cholesterol complex.

Chang TY, Chang C.

Cell Metab. 2008 Jun;7(6):469-71. doi: 10.1016/j.cmet.2008.05.001. Review.

16.

Niemann-Pick C1-like 1 overexpression facilitates ezetimibe-sensitive cholesterol and beta-sitosterol uptake in CaCo-2 cells.

Yamanashi Y, Takada T, Suzuki H.

J Pharmacol Exp Ther. 2007 Feb;320(2):559-64. Epub 2006 Nov 29.

17.

Membrane topology of human NPC1L1, a key protein in enterohepatic cholesterol absorption.

Wang J, Chu BB, Ge L, Li BL, Yan Y, Song BL.

J Lipid Res. 2009 Aug;50(8):1653-62. doi: 10.1194/jlr.M800669-JLR200. Epub 2009 Mar 26.

18.

Inhibition of hepatic Niemann-Pick C1-like 1 improves hepatic insulin resistance.

Nomura M, Ishii H, Kawakami A, Yoshida M.

Am J Physiol Endocrinol Metab. 2009 Nov;297(5):E1030-8. doi: 10.1152/ajpendo.00343.2009. Epub 2009 Aug 4.

19.

Flotillins play an essential role in Niemann-Pick C1-like 1-mediated cholesterol uptake.

Ge L, Qi W, Wang LJ, Miao HH, Qu YX, Li BL, Song BL.

Proc Natl Acad Sci U S A. 2011 Jan 11;108(2):551-6. doi: 10.1073/pnas.1014434108. Epub 2010 Dec 27.

20.

Multiple plasma membrane receptors but not NPC1L1 mediate high-affinity, ezetimibe-sensitive cholesterol uptake into the intestinal brush border membrane.

Knöpfel M, Davies JP, Duong PT, Kvaernø L, Carreira EM, Phillips MC, Ioannou YA, Hauser H.

Biochim Biophys Acta. 2007 Sep;1771(9):1140-7. Epub 2007 Jun 23.

PMID:
17689140
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