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Items: 1 to 20 of 97

1.

LXRs regulate ER stress and inflammation through dynamic modulation of membrane phospholipid composition.

Rong X, Albert CJ, Hong C, Duerr MA, Chamberlain BT, Tarling EJ, Ito A, Gao J, Wang B, Edwards PA, Jung ME, Ford DA, Tontonoz P.

Cell Metab. 2013 Nov 5;18(5):685-97. doi: 10.1016/j.cmet.2013.10.002.

2.

Lpcat3-dependent production of arachidonoyl phospholipids is a key determinant of triglyceride secretion.

Rong X, Wang B, Dunham MM, Hedde PN, Wong JS, Gratton E, Young SG, Ford DA, Tontonoz P.

Elife. 2015 Mar 25;4. doi: 10.7554/eLife.06557.

3.

Liver x receptor regulates arachidonic acid distribution and eicosanoid release in human macrophages: a key role for lysophosphatidylcholine acyltransferase 3.

Ishibashi M, Varin A, Filomenko R, Lopez T, Athias A, Gambert P, Blache D, Thomas C, Gautier T, Lagrost L, Masson D.

Arterioscler Thromb Vasc Biol. 2013 Jun;33(6):1171-9. doi: 10.1161/ATVBAHA.112.300812. Epub 2013 Apr 11.

4.

Decrease in membrane phospholipid unsaturation induces unfolded protein response.

Ariyama H, Kono N, Matsuda S, Inoue T, Arai H.

J Biol Chem. 2010 Jul 16;285(29):22027-35. doi: 10.1074/jbc.M110.126870. Epub 2010 May 20.

5.

Deficiency in lysophosphatidylcholine acyltransferase 3 reduces plasma levels of lipids by reducing lipid absorption in mice.

Li Z, Jiang H, Ding T, Lou C, Bui HH, Kuo MS, Jiang XC.

Gastroenterology. 2015 Nov;149(6):1519-29. doi: 10.1053/j.gastro.2015.07.012. Epub 2015 Jul 27.

PMID:
26226572
6.

Fatty acid remodeling by LPCAT3 enriches arachidonate in phospholipid membranes and regulates triglyceride transport.

Hashidate-Yoshida T, Harayama T, Hishikawa D, Morimoto R, Hamano F, Tokuoka SM, Eto M, Tamura-Nakano M, Yanobu-Takanashi R, Mukumoto Y, Kiyonari H, Okamura T, Kita Y, Shindou H, Shimizu T.

Elife. 2015 Apr 21;4. doi: 10.7554/eLife.06328.

7.

Substrate preferences of a lysophosphatidylcholine acyltransferase highlight its role in phospholipid remodeling.

Kazachkov M, Chen Q, Wang L, Zou J.

Lipids. 2008 Oct;43(10):895-902. doi: 10.1007/s11745-008-3233-y. Epub 2008 Sep 10.

PMID:
18781350
8.

Identification and characterization of a major liver lysophosphatidylcholine acyltransferase.

Zhao Y, Chen YQ, Bonacci TM, Bredt DS, Li S, Bensch WR, Moller DE, Kowala M, Konrad RJ, Cao G.

J Biol Chem. 2008 Mar 28;283(13):8258-65. doi: 10.1074/jbc.M710422200. Epub 2008 Jan 14.

9.

Regulation of LPCAT3 by LXR.

Demeure O, Lecerf F, Duby C, Desert C, Ducheix S, Guillou H, Lagarrigue S.

Gene. 2011 Jan 1;470(1-2):7-11. doi: 10.1016/j.gene.2010.09.002. Epub 2010 Sep 15.

PMID:
20837115
10.

Polyunsaturated fatty acid-phospholipid remodeling and inflammation.

Robichaud PP, Surette ME.

Curr Opin Endocrinol Diabetes Obes. 2015 Apr;22(2):112-8. doi: 10.1097/MED.0000000000000138. Review.

PMID:
25692925
11.

LXRs link metabolism to inflammation through Abca1-dependent regulation of membrane composition and TLR signaling.

Ito A, Hong C, Rong X, Zhu X, Tarling EJ, Hedde PN, Gratton E, Parks J, Tontonoz P.

Elife. 2015 Jul 14;4:e08009. doi: 10.7554/eLife.08009.

12.
13.
14.

Astaxanthin reduces hepatic endoplasmic reticulum stress and nuclear factor-κB-mediated inflammation in high fructose and high fat diet-fed mice.

Bhuvaneswari S, Yogalakshmi B, Sreeja S, Anuradha CV.

Cell Stress Chaperones. 2014 Mar;19(2):183-91. doi: 10.1007/s12192-013-0443-x. Epub 2013 Jul 14.

15.

Endoplasmic reticulum stress leads to lipid accumulation through upregulation of SREBP-1c in normal hepatic and hepatoma cells.

Fang DL, Wan Y, Shen W, Cao J, Sun ZX, Yu HH, Zhang Q, Cheng WH, Chen J, Ning B.

Mol Cell Biochem. 2013 Sep;381(1-2):127-37. doi: 10.1007/s11010-013-1694-7. Epub 2013 May 24.

PMID:
23703028
16.

Lysophospholipid metabolism facilitates Toll-like receptor 4 membrane translocation to regulate the inflammatory response.

Jackson SK, Abate W, Parton J, Jones S, Harwood JL.

J Leukoc Biol. 2008 Jul;84(1):86-92. doi: 10.1189/jlb.0907601. Epub 2008 Apr 10.

17.

Inflammatory stress exacerbates lipid accumulation in hepatic cells and fatty livers of apolipoprotein E knockout mice.

Ma KL, Ruan XZ, Powis SH, Chen Y, Moorhead JF, Varghese Z.

Hepatology. 2008 Sep;48(3):770-81. doi: 10.1002/hep.22423.

PMID:
18752326
18.

Lysophosphatidylcholine acyltransferase 3 knockdown-mediated liver lysophosphatidylcholine accumulation promotes very low density lipoprotein production by enhancing microsomal triglyceride transfer protein expression.

Li Z, Ding T, Pan X, Li Y, Li R, Sanders PE, Kuo MS, Hussain MM, Cao G, Jiang XC.

J Biol Chem. 2012 Jun 8;287(24):20122-31. doi: 10.1074/jbc.M111.334664. Epub 2012 Apr 17.

19.

Characterization of human lysophospholipid acyltransferase 3.

Jain S, Zhang X, Khandelwal PJ, Saunders AJ, Cummings BS, Oelkers P.

J Lipid Res. 2009 Aug;50(8):1563-70. doi: 10.1194/jlr.M800398-JLR200. Epub 2009 Apr 7.

20.

Phospholipid modifications influence acyl-CoA:1-acyl-glycero-3-phosphocholine O-acyltransferase in rat liver plasma membranes.

Momchilova AB, Markovska TT, Koshlukova SE, Koumanov KS, Pankov RG.

Biochem Cell Biol. 1991 Sep;69(9):643-8.

PMID:
1793566
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