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Similar articles for PubMed (Select 24203393)

1.

Structural design, synthesis and structure-activity relationships of thiazolidinones with enhanced anti-Trypanosoma cruzi activity.

Moreira DR, Leite AC, Cardoso MV, Srivastava RM, Hernandes MZ, Rabello MM, da Cruz LF, Ferreira RS, de Simone CA, Meira CS, Guimaraes ET, da Silva AC, dos Santos TA, Pereira VR, Soares MB.

ChemMedChem. 2014 Jan;9(1):177-88. doi: 10.1002/cmdc.201300354. Epub 2013 Nov 7.

PMID:
24203393
2.

Structural investigation of anti-Trypanosoma cruzi 2-iminothiazolidin-4-ones allows the identification of agents with efficacy in infected mice.

Moreira DR, Costa SP, Hernandes MZ, Rabello MM, de Oliveira Filho GB, de Melo CM, da Rocha LF, de Simone CA, Ferreira RS, Fradico JR, Meira CS, Guimarães ET, Srivastava RM, Pereira VR, Soares MB, Leite AC.

J Med Chem. 2012 Dec 27;55(24):10918-36. doi: 10.1021/jm301518v. Epub 2012 Dec 7.

PMID:
23167554
3.

Conformational restriction of aryl thiosemicarbazones produces potent and selective anti-Trypanosoma cruzi compounds which induce apoptotic parasite death.

Magalhaes Moreira DR, de Oliveira AD, Teixeira de Moraes Gomes PA, de Simone CA, Villela FS, Ferreira RS, da Silva AC, dos Santos TA, Brelaz de Castro MC, Pereira VR, Leite AC.

Eur J Med Chem. 2014 Mar 21;75:467-78. doi: 10.1016/j.ejmech.2014.02.001. Epub 2014 Feb 3.

PMID:
24561675
4.

Design, synthesis and cruzain docking of 3-(4-substituted-aryl)-1,2,4-oxadiazole-N-acylhydrazones as anti-Trypanosoma cruzi agents.

dos Santos Filho JM, Leite AC, de Oliveira BG, Moreira DR, Lima MS, Soares MB, Leite LF.

Bioorg Med Chem. 2009 Sep 15;17(18):6682-91. doi: 10.1016/j.bmc.2009.07.068. Epub 2009 Aug 6.

PMID:
19683450
5.

Synthesis, biological evaluation, and structure-activity relationships of potent noncovalent and nonpeptidic cruzain inhibitors as anti-Trypanosoma cruzi agents.

Ferreira RS, Dessoy MA, Pauli I, Souza ML, Krogh R, Sales AI, Oliva G, Dias LC, Andricopulo AD.

J Med Chem. 2014 Mar 27;57(6):2380-92. doi: 10.1021/jm401709b. Epub 2014 Mar 3.

PMID:
24533839
6.

Optimization of anti-Trypanosoma cruzi oxadiazoles leads to identification of compounds with efficacy in infected mice.

dos Santos Filho JM, Moreira DR, de Simone CA, Ferreira RS, McKerrow JH, Meira CS, Guimarães ET, Soares MB.

Bioorg Med Chem. 2012 Nov 1;20(21):6423-33. doi: 10.1016/j.bmc.2012.08.047. Epub 2012 Aug 31.

7.

Aryl ureas represent a new class of anti-trypanosomal agents.

Du X, Hansell E, Engel JC, Caffrey CR, Cohen FE, McKerrow JH.

Chem Biol. 2000 Sep;7(9):733-42.

8.

In vitro and in vivo studies of the antiparasitic activity of sterol 14α-demethylase (CYP51) inhibitor VNI against drug-resistant strains of Trypanosoma cruzi.

Soeiro Mde N, de Souza EM, da Silva CF, Batista Dda G, Batista MM, Pavão BP, Araújo JS, Aiub CA, da Silva PB, Lionel J, Britto C, Kim K, Sulikowski G, Hargrove TY, Waterman MR, Lepesheva GI.

Antimicrob Agents Chemother. 2013 Sep;57(9):4151-63. doi: 10.1128/AAC.00070-13. Epub 2013 Jun 17.

9.

Physalins B and F, seco-steroids isolated from Physalis angulata L., strongly inhibit proliferation, ultrastructure and infectivity of Trypanosoma cruzi.

Meira CS, Guimarães ET, Bastos TM, Moreira DR, Tomassini TC, Ribeiro IM, Dos Santos RR, Soares MB.

Parasitology. 2013 Dec;140(14):1811-21. doi: 10.1017/S0031182013001297. Epub 2013 Sep 4.

PMID:
24001147
10.

Synthesis, trypanocidal activity and docking studies of novel quinoxaline-N-acylhydrazones, designed as cruzain inhibitors candidates.

Romeiro NC, Aguirre G, Hernández P, González M, Cerecetto H, Aldana I, Pérez-Silanes S, Monge A, Barreiro EJ, Lima LM.

Bioorg Med Chem. 2009 Jan 15;17(2):641-52. doi: 10.1016/j.bmc.2008.11.065. Epub 2008 Dec 3.

PMID:
19110434
11.

Design, synthesis and biological evaluation of potent azadipeptide nitrile inhibitors and activity-based probes as promising anti-Trypanosoma brucei agents.

Yang PY, Wang M, Li L, Wu H, He CY, Yao SQ.

Chemistry. 2012 May 21;18(21):6528-41. doi: 10.1002/chem.201103322. Epub 2012 Apr 4.

PMID:
22488888
12.

Synthesis, Cruzain docking, and in vitro studies of aryl-4-oxothiazolylhydrazones against Trypanosoma cruzi.

Leite AC, Moreira DR, Cardoso MV, Hernandes MZ, Alves Pereira VR, Silva RO, Kiperstok AC, Lima Mda S, Soares MB.

ChemMedChem. 2007 Sep;2(9):1339-45.

PMID:
17628867
13.

In vitro and in vivo studies of the trypanocidal properties of WRR-483 against Trypanosoma cruzi.

Chen YT, Brinen LS, Kerr ID, Hansell E, Doyle PS, McKerrow JH, Roush WR.

PLoS Negl Trop Dis. 2010 Sep 14;4(9). pii: e825. doi: 10.1371/journal.pntd.0000825.

14.

Nitro/nitrosyl-ruthenium complexes are potent and selective anti-Trypanosoma cruzi agents causing autophagy and necrotic parasite death.

Bastos TM, Barbosa MI, da Silva MM, da C Júnior JW, Meira CS, Guimaraes ET, Ellena J, Moreira DR, Batista AA, Soares MB.

Antimicrob Agents Chemother. 2014 Oct;58(10):6044-55. doi: 10.1128/AAC.02765-14. Epub 2014 Aug 4.

15.

Design and synthesis of new (E)-cinnamic N-acylhydrazones as potent antitrypanosomal agents.

Carvalho SA, Feitosa LO, Soares M, Costa TE, Henriques MG, Salomão K, de Castro SL, Kaiser M, Brun R, Wardell JL, Wardell SM, Trossini GH, Andricopulo AD, da Silva EF, Fraga CA.

Eur J Med Chem. 2012 Aug;54:512-21. doi: 10.1016/j.ejmech.2012.05.041. Epub 2012 Jun 7.

PMID:
22727447
16.

Potent second generation vinyl sulfonamide inhibitors of the trypanosomal cysteine protease cruzain.

Roush WR, Cheng J, Knapp-Reed B, Alvarez-Hernandez A, McKerrow JH, Hansell E, Engel JC.

Bioorg Med Chem Lett. 2001 Oct 22;11(20):2759-62.

PMID:
11591518
17.

Identification of novel benzimidazole derivatives as anti-Trypanosoma cruzi agents: solid-phase synthesis, structure-activity relationships and molecular docking studies.

Ríos N, Varela J, Birriel E, González M, Cerecetto H, Merlino A, Porcal W.

Future Med Chem. 2013 Oct;5(15):1719-32. doi: 10.4155/fmc.13.160.

PMID:
24144409
18.

Nonpeptidic tetrafluorophenoxymethyl ketone cruzain inhibitors as promising new leads for Chagas disease chemotherapy.

Brak K, Kerr ID, Barrett KT, Fuchi N, Debnath M, Ang K, Engel JC, McKerrow JH, Doyle PS, Brinen LS, Ellman JA.

J Med Chem. 2010 Feb 25;53(4):1763-73. doi: 10.1021/jm901633v.

19.

A quinoxaline derivative as a potent chemotherapeutic agent, alone or in combination with benznidazole, against Trypanosoma cruzi.

Rodrigues JH, Ueda-Nakamura T, Corrêa AG, Sangi DP, Nakamura CV.

PLoS One. 2014 Jan 17;9(1):e85706. doi: 10.1371/journal.pone.0085706. eCollection 2014.

20.

Synthesis of pyrazoline-thiazolidinone hybrids with trypanocidal activity.

Havrylyuk D, Zimenkovsky B, Karpenko O, Grellier P, Lesyk R.

Eur J Med Chem. 2014 Oct 6;85:245-54. doi: 10.1016/j.ejmech.2014.07.103. Epub 2014 Jul 30.

PMID:
25089808
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