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Results: 1 to 20 of 103

Similar articles for PubMed (Select 24196086)

1.

Toxicology study assessing efficacy and safety of repeated administration of lipid/DNA complexes to mouse lung.

Alton EW, Boyd AC, Cheng SH, Davies JC, Davies LA, Dayan A, Gill DR, Griesenbach U, Higgins T, Hyde SC, Innes JA, McLachlan G, Porteous D, Pringle I, Scheule RK, Sumner-Jones S.

Gene Ther. 2014 Jan;21(1):89-95. doi: 10.1038/gt.2013.61. Epub 2013 Nov 7.

PMID:
24196086
2.

Aerosol delivery of DNA/liposomes to the lung for cystic fibrosis gene therapy.

Davies LA, Nunez-Alonso GA, McLachlan G, Hyde SC, Gill DR.

Hum Gene Ther Clin Dev. 2014 Jun;25(2):97-107. doi: 10.1089/humc.2014.019. Epub 2014 May 27.

PMID:
24865497
3.

Pre-clinical evaluation of three non-viral gene transfer agents for cystic fibrosis after aerosol delivery to the ovine lung.

McLachlan G, Davidson H, Holder E, Davies LA, Pringle IA, Sumner-Jones SG, Baker A, Tennant P, Gordon C, Vrettou C, Blundell R, Hyndman L, Stevenson B, Wilson A, Doherty A, Shaw DJ, Coles RL, Painter H, Cheng SH, Scheule RK, Davies JC, Innes JA, Hyde SC, Griesenbach U, Alton EW, Boyd AC, Porteous DJ, Gill DR, Collie DD.

Gene Ther. 2011 Oct;18(10):996-1005. doi: 10.1038/gt.2011.55. Epub 2011 Apr 21.

PMID:
21512505
4.

CpG-free plasmid expression cassettes for cystic fibrosis gene therapy.

Pringle IA, Hyde SC, Connolly MM, Lawton AE, Xu B, Nunez-Alonso G, Davies LA, Sumner-Jones SG, Gill DR.

Biomaterials. 2012 Oct;33(28):6833-42. doi: 10.1016/j.biomaterials.2012.06.009. Epub 2012 Jun 22.

PMID:
22727465
5.

Repeated adeno-associated virus serotype 2 aerosol-mediated cystic fibrosis transmembrane regulator gene transfer to the lungs of patients with cystic fibrosis: a multicenter, double-blind, placebo-controlled trial.

Moss RB, Rodman D, Spencer LT, Aitken ML, Zeitlin PL, Waltz D, Milla C, Brody AS, Clancy JP, Ramsey B, Hamblett N, Heald AE.

Chest. 2004 Feb;125(2):509-21.

PMID:
14769732
6.

The safety profile of a cationic lipid-mediated cystic fibrosis gene transfer agent following repeated monthly aerosol administration to sheep.

Alton EW, Baker A, Baker E, Boyd AC, Cheng SH, Coles RL, Collie DD, Davidson H, Davies JC, Gill DR, Gordon C, Griesenbach U, Higgins T, Hyde SC, Innes JA, McCormick D, McGovern M, McLachlan G, Porteous DJ, Pringle I, Scheule RK, Shaw DJ, Smith S, Sumner-Jones SG, Tennant P, Vrettou C.

Biomaterials. 2013 Dec;34(38):10267-77. doi: 10.1016/j.biomaterials.2013.09.023. Epub 2013 Oct 3.

PMID:
24090839
7.

Detailed analysis of structures and formulations of cationic lipids for efficient gene transfer to the lung.

Lee ER, Marshall J, Siegel CS, Jiang C, Yew NS, Nichols MR, Nietupski JB, Ziegler RJ, Lane MB, Wang KX, Wan NC, Scheule RK, Harris DJ, Smith AE, Cheng SH.

Hum Gene Ther. 1996 Sep 10;7(14):1701-17.

PMID:
8886841
8.

Aerosol and lobar administration of a recombinant adenovirus to individuals with cystic fibrosis. I. Methods, safety, and clinical implications.

Joseph PM, O'Sullivan BP, Lapey A, Dorkin H, Oren J, Balfour R, Perricone MA, Rosenberg M, Wadsworth SC, Smith AE, St George JA, Meeker DP.

Hum Gene Ther. 2001 Jul 20;12(11):1369-82.

PMID:
11485629
9.

Repeat administration of DNA/liposomes to the nasal epithelium of patients with cystic fibrosis.

Hyde SC, Southern KW, Gileadi U, Fitzjohn EM, Mofford KA, Waddell BE, Gooi HC, Goddard CA, Hannavy K, Smyth SE, Egan JJ, Sorgi FL, Huang L, Cuthbert AW, Evans MJ, Colledge WH, Higgins CF, Webb AK, Gill DR.

Gene Ther. 2000 Jul;7(13):1156-65.

10.

Comparison of DNA-lipid complexes and DNA alone for gene transfer to cystic fibrosis airway epithelia in vivo.

Zabner J, Cheng SH, Meeker D, Launspach J, Balfour R, Perricone MA, Morris JE, Marshall J, Fasbender A, Smith AE, Welsh MJ.

J Clin Invest. 1997 Sep 15;100(6):1529-37.

11.

Gene therapy in cystic fibrosis.

Flotte TR, Laube BL.

Chest. 2001 Sep;120(3 Suppl):124S-131S. Review.

PMID:
11555567
12.

Vector-specific complementation profiles of two independent primary defects in cystic fibrosis airways.

Zhang Y, Jiang Q, Dudus L, Yankaskas JR, Engelhardt JF.

Hum Gene Ther. 1998 Mar 20;9(5):635-48.

PMID:
9551612
13.

Cationic lipid:pDNA complexes for the treatment of cystic fibrosis.

Eastman SJ, Scheule RK.

Curr Opin Mol Ther. 1999 Apr;1(2):186-96. Review.

PMID:
11715942
14.

Basis of pulmonary toxicity associated with cationic lipid-mediated gene transfer to the mammalian lung.

Scheule RK, St George JA, Bagley RG, Marshall J, Kaplan JM, Akita GY, Wang KX, Lee ER, Harris DJ, Jiang C, Yew NS, Smith AE, Cheng SH.

Hum Gene Ther. 1997 Apr 10;8(6):689-707.

PMID:
9113509
15.

Non-viral approach toward gene therapy of cystic fibrosis lung disease.

Bragonzi A, Conese M.

Curr Gene Ther. 2002 Sep;2(3):295-305. Review.

PMID:
12189717
16.

Cationic lipid-mediated CFTR gene transfer to the lungs and nose of patients with cystic fibrosis: a double-blind placebo-controlled trial.

Alton EW, Stern M, Farley R, Jaffe A, Chadwick SL, Phillips J, Davies J, Smith SN, Browning J, Davies MG, Hodson ME, Durham SR, Li D, Jeffery PK, Scallan M, Balfour R, Eastman SJ, Cheng SH, Smith AE, Meeker D, Geddes DM.

Lancet. 1999 Mar 20;353(9157):947-54.

PMID:
10459902
17.

Safety of single-dose administration of an adeno-associated virus (AAV)-CFTR vector in the primate lung.

Conrad CK, Allen SS, Afione SA, Reynolds TC, Beck SE, Fee-Maki M, Barrazza-Ortiz X, Adams R, Askin FB, Carter BJ, Guggino WB, Flotte TR.

Gene Ther. 1996 Aug;3(8):658-68.

PMID:
8854091
18.

Technology evaluation: cystic fibrosis therapy, Genzyme.

Cockett MI.

Curr Opin Mol Ther. 1999 Apr;1(2):279-83. Review.

PMID:
11715952
19.

The role of doxorubicin in non-viral gene transfer in the lung.

Griesenbach U, Meng C, Farley R, Gardner A, Brake MA, Frankel GM, Gruenert DC, Cheng SH, Scheule RK, Alton EW.

Biomaterials. 2009 Apr;30(10):1971-7. doi: 10.1016/j.biomaterials.2008.12.037. Epub 2009 Jan 18.

PMID:
19152975
20.

Is gene therapy in cystic fibrosis a realistic expectation?

McElvaney NG.

Curr Opin Pulm Med. 1996 Nov;2(6):466-71. Review.

PMID:
9363187
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