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Results: 1 to 20 of 116

1.

Restricted expression of miR-30c-2-3p and miR-30a-3p in clear cell renal cell carcinomas enhances HIF2α activity.

Mathew LK, Lee SS, Skuli N, Rao S, Keith B, Nathanson KL, Lal P, Simon MC.

Cancer Discov. 2014 Jan;4(1):53-60. doi: 10.1158/2159-8290.CD-13-0291. Epub 2013 Nov 4.

PMID:
24189146
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

miR-30c-2-3p and miR-30a-3p: new pieces of the jigsaw puzzle in HIF2α regulation.

Moch H, Lukamowicz-Rajska M.

Cancer Discov. 2014 Jan;4(1):22-4. doi: 10.1158/2159-8290.CD-13-0897.

PMID:
24402943
[PubMed - indexed for MEDLINE]
3.

Targeting HIF2α translation with Tempol in VHL-deficient clear cell renal cell carcinoma.

Sourbier C, Srivastava G, Ghosh MC, Ghosh S, Yang Y, Gupta G, Degraff W, Krishna MC, Mitchell JB, Rouault TA, Linehan WM.

Oncotarget. 2012 Nov;3(11):1472-82.

PMID:
23178531
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

The von Hippel-Lindau tumor suppressor protein regulates gene expression and tumor growth through histone demethylase JARID1C.

Niu X, Zhang T, Liao L, Zhou L, Lindner DJ, Zhou M, Rini B, Yan Q, Yang H.

Oncogene. 2012 Feb 9;31(6):776-86. doi: 10.1038/onc.2011.266. Epub 2011 Jul 4.

PMID:
21725364
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Prolyl hydroxylase 2 dependent and Von-Hippel-Lindau independent degradation of Hypoxia-inducible factor 1 and 2 alpha by selenium in clear cell renal cell carcinoma leads to tumor growth inhibition.

Chintala S, Najrana T, Toth K, Cao S, Durrani FA, Pili R, Rustum YM.

BMC Cancer. 2012 Jul 17;12:293. doi: 10.1186/1471-2407-12-293.

PMID:
22804960
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

The VHL-dependent regulation of microRNAs in renal cancer.

Neal CS, Michael MZ, Rawlings LH, Van der Hoek MB, Gleadle JM.

BMC Med. 2010 Oct 21;8:64. doi: 10.1186/1741-7015-8-64.

PMID:
20964835
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Deletions of chromosomes 3p and 14q molecularly subclassify clear cell renal cell carcinoma.

Kroeger N, Klatte T, Chamie K, Rao PN, Birkhäuser FD, Sonn GA, Riss J, Kabbinavar FF, Belldegrun AS, Pantuck AJ.

Cancer. 2013 Apr 15;119(8):1547-54. doi: 10.1002/cncr.27947. Epub 2013 Jan 18.

PMID:
23335244
[PubMed - indexed for MEDLINE]
8.

Dysregulated D-dopachrome tautomerase, a hypoxia-inducible factor-dependent gene, cooperates with macrophage migration inhibitory factor in renal tumorigenesis.

Pasupuleti V, Du W, Gupta Y, Yeh IJ, Montano M, Magi-Galuzzi C, Welford SM.

J Biol Chem. 2014 Feb 7;289(6):3713-23. doi: 10.1074/jbc.M113.500694. Epub 2013 Dec 19.

PMID:
24356968
[PubMed - indexed for MEDLINE]
9.
10.

Loss of VHL and hypoxia provokes PAX2 up-regulation in clear cell renal cell carcinoma.

Luu VD, Boysen G, Struckmann K, Casagrande S, von Teichman A, Wild PJ, Sulser T, Schraml P, Moch H.

Clin Cancer Res. 2009 May 15;15(10):3297-304. doi: 10.1158/1078-0432.CCR-08-2779. Epub 2009 Apr 28.

PMID:
19401348
[PubMed - indexed for MEDLINE]
Free Article
11.

Hypoxia-induced downregulation of miR-30c promotes epithelial-mesenchymal transition in human renal cell carcinoma.

Huang J, Yao X, Zhang J, Dong B, Chen Q, Xue W, Liu D, Huang Y.

Cancer Sci. 2013 Dec;104(12):1609-17. doi: 10.1111/cas.12291. Epub 2013 Oct 27.

PMID:
24112779
[PubMed - indexed for MEDLINE]
12.

Up-regulation of hypoxia-inducible factor 2alpha in renal cell carcinoma associated with loss of Tsc-2 tumor suppressor gene.

Liu MY, Poellinger L, Walker CL.

Cancer Res. 2003 May 15;63(10):2675-80.

PMID:
12750296
[PubMed - indexed for MEDLINE]
Free Article
13.

[The expression of hypoxia inducible factor-1,2 alpha in sporadic clear cell renal cell carcinoma and their relationships to the mutations of von Hippel-Lindau gene].

Gong K, Zhang N, Na X, Wu G, Yang XY, Xin DQ, Na YQ.

Zhonghua Wai Ke Za Zhi. 2005 Mar 15;43(6):390-3. Chinese.

PMID:
15854350
[PubMed - indexed for MEDLINE]
14.

Constitutive activation of hypoxia-inducible genes related to overexpression of hypoxia-inducible factor-1alpha in clear cell renal carcinomas.

Wiesener MS, Münchenhagen PM, Berger I, Morgan NV, Roigas J, Schwiertz A, Jürgensen JS, Gruber G, Maxwell PH, Löning SA, Frei U, Maher ER, Gröne HJ, Eckardt KU.

Cancer Res. 2001 Jul 1;61(13):5215-22.

PMID:
11431362
[PubMed - indexed for MEDLINE]
Free Article
15.

HIF alpha expression in VHL-deficient renal cancer cells is dependent on phospholipase D.

Toschi A, Edelstein J, Rockwell P, Ohh M, Foster DA.

Oncogene. 2008 Apr 24;27(19):2746-53. Epub 2007 Nov 12.

PMID:
17998935
[PubMed - indexed for MEDLINE]
16.

The von Hippel-Lindau tumor suppressor protein promotes c-Cbl-independent poly-ubiquitylation and degradation of the activated EGFR.

Zhou L, Yang H.

PLoS One. 2011;6(9):e23936. doi: 10.1371/journal.pone.0023936. Epub 2011 Sep 16.

PMID:
21949687
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Proteomic analysis of signaling network regulation in renal cell carcinomas with differential hypoxia-inducible factor-2α expression.

Nagaprashantha LD, Talamantes T, Singhal J, Guo J, Vatsyayan R, Rauniyar N, Awasthi S, Singhal SS, Prokai L.

PLoS One. 2013 Aug 5;8(8):e71654. doi: 10.1371/journal.pone.0071654. Print 2013.

PMID:
23940778
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Expression of fibronectin and HIF-1alpha in renal cell carcinomas: relationship to von Hippel-Lindau gene inactivation.

He Z, Liu S, Guo M, Mao J, Hughson MD.

Cancer Genet Cytogenet. 2004 Jul 15;152(2):89-94.

PMID:
15262424
[PubMed - indexed for MEDLINE]
19.

HIF2α acts as an mTORC1 activator through the amino acid carrier SLC7A5.

Elorza A, Soro-Arnáiz I, Meléndez-Rodríguez F, Rodríguez-Vaello V, Marsboom G, de Cárcer G, Acosta-Iborra B, Albacete-Albacete L, Ordóñez A, Serrano-Oviedo L, Giménez-Bachs JM, Vara-Vega A, Salinas A, Sánchez-Prieto R, Martín del Río R, Sánchez-Madrid F, Malumbres M, Landázuri MO, Aragonés J.

Mol Cell. 2012 Dec 14;48(5):681-91. doi: 10.1016/j.molcel.2012.09.017. Epub 2012 Oct 25.

PMID:
23103253
[PubMed - indexed for MEDLINE]
Free Article
20.

Genetic and functional studies implicate HIF1α as a 14q kidney cancer suppressor gene.

Shen C, Beroukhim R, Schumacher SE, Zhou J, Chang M, Signoretti S, Kaelin WG Jr.

Cancer Discov. 2011 Aug;1(3):222-35. doi: 10.1158/2159-8290.CD-11-0098. Epub 2011 Jun 7.

PMID:
22037472
[PubMed - indexed for MEDLINE]
Free PMC Article

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