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GLP-1R responsiveness predicts individual gastric bypass efficacy on glucose tolerance in rats.

Habegger KM, Heppner KM, Amburgy SE, Ottaway N, Holland J, Raver C, Bartley E, Müller TD, Pfluger PT, Berger J, Toure M, Benoit SC, Dimarchi RD, Perez-Tilve D, D'Alessio DA, Seeley RJ, Tschöp MH.

Diabetes. 2014 Feb;63(2):505-13. doi: 10.2337/db13-0511. Epub 2013 Nov 1.


GLP-1R agonism enhances adjustable gastric banding in diet-induced obese rats.

Habegger KM, Kirchner H, Yi CX, Heppner KM, Sweeney D, Ottaway N, Holland J, Amburgy S, Raver C, Krishna R, Müller TD, Perez-Tilve D, Pfluger PT, Obici S, DiMarchi RD, D'Alessio DA, Seeley RJ, Tschöp MH.

Diabetes. 2013 Sep;62(9):3261-7. doi: 10.2337/db13-0117. Epub 2013 Jun 17.


Roux-en-Y gastric bypass-induced improvement of glucose tolerance and insulin resistance in type 2 diabetic rats are mediated by glucagon-like peptide-1.

Liu Y, Zhou Y, Wang Y, Geng D, Liu J.

Obes Surg. 2011 Sep;21(9):1424-31. doi: 10.1007/s11695-011-0388-z.


GLP-1 receptor signaling is not required for reduced body weight after RYGB in rodents.

Ye J, Hao Z, Mumphrey MB, Townsend RL, Patterson LM, Stylopoulos N, Münzberg H, Morrison CD, Drucker DJ, Berthoud HR.

Am J Physiol Regul Integr Comp Physiol. 2014 Mar 1;306(5):R352-62. doi: 10.1152/ajpregu.00491.2013. Epub 2014 Jan 15.


Weight-independent changes in blood glucose homeostasis after gastric bypass or vertical sleeve gastrectomy in rats.

Chambers AP, Jessen L, Ryan KK, Sisley S, Wilson-Pérez HE, Stefater MA, Gaitonde SG, Sorrell JE, Toure M, Berger J, D'Alessio DA, Woods SC, Seeley RJ, Sandoval DA.

Gastroenterology. 2011 Sep;141(3):950-8. doi: 10.1053/j.gastro.2011.05.050. Epub 2011 Jul 12.


Roux-en-Y gastric bypass in rats increases sucrose taste-related motivated behavior independent of pharmacological GLP-1-receptor modulation.

Mathes CM, Bueter M, Smith KR, Lutz TA, le Roux CW, Spector AC.

Am J Physiol Regul Integr Comp Physiol. 2012 Mar 15;302(6):R751-67. doi: 10.1152/ajpregu.00214.2011. Epub 2011 Dec 14.


Acute peripheral GLP-1 receptor agonism or antagonism does not alter energy expenditure in rats after Roux-en-Y gastric bypass.

Abegg K, Schiesser M, Lutz TA, Bueter M.

Physiol Behav. 2013 Sep 10;121:70-8. doi: 10.1016/j.physbeh.2013.03.027. Epub 2013 Apr 3.


Exogenous peptide YY3-36 and Exendin-4 further decrease food intake, whereas octreotide increases food intake in rats after Roux-en-Y gastric bypass.

Fenske WK, Bueter M, Miras AD, Ghatei MA, Bloom SR, le Roux CW.

Int J Obes (Lond). 2012 Mar;36(3):379-84. doi: 10.1038/ijo.2011.126. Epub 2011 Jun 21.


High-fat diet changes the temporal profile of GLP-1 receptor-mediated hypophagia in rats.

Mul JD, Begg DP, Barrera JG, Li B, Matter EK, D'Alessio DA, Woods SC, Seeley RJ, Sandoval DA.

Am J Physiol Regul Integr Comp Physiol. 2013 Jul 1;305(1):R68-77. doi: 10.1152/ajpregu.00588.2012. Epub 2013 Apr 24.


Rapid and body weight-independent improvement of endothelial and high-density lipoprotein function after Roux-en-Y gastric bypass: role of glucagon-like peptide-1.

Osto E, Doytcheva P, Corteville C, Bueter M, Dörig C, Stivala S, Buhmann H, Colin S, Rohrer L, Hasballa R, Tailleux A, Wolfrum C, Tona F, Manz J, Vetter D, Spliethoff K, Vanhoutte PM, Landmesser U, Pattou F, Staels B, Matter CM, Lutz TA, Lüscher TF.

Circulation. 2015 Mar 10;131(10):871-81. doi: 10.1161/CIRCULATIONAHA.114.011791. Epub 2015 Feb 11.


Mechanisms of glucose homeostasis after Roux-en-Y gastric bypass surgery in the obese, insulin-resistant Zucker rat.

Meirelles K, Ahmed T, Culnan DM, Lynch CJ, Lang CH, Cooney RN.

Ann Surg. 2009 Feb;249(2):277-85. doi: 10.1097/SLA.0b013e3181904af0.


The role of the gut hormone GLP-1 in the metabolic improvements caused by ileal transposition.

Gaitonde S, Kohli R, Seeley R.

J Surg Res. 2012 Nov;178(1):33-9. doi: 10.1016/j.jss.2011.04.044. Epub 2011 May 18.


Exaggerated glucagon-like peptide 1 response is important for improved β-cell function and glucose tolerance after Roux-en-Y gastric bypass in patients with type 2 diabetes.

Jørgensen NB, Dirksen C, Bojsen-Møller KN, Jacobsen SH, Worm D, Hansen DL, Kristiansen VB, Naver L, Madsbad S, Holst JJ.

Diabetes. 2013 Sep;62(9):3044-52. doi: 10.2337/db13-0022. Epub 2013 May 6.


Clozapine and quetiapine acutely reduce glucagon-like peptide-1 production and increase glucagon release in obese rats: implications for glucose metabolism and food choice behaviour.

Smith GC, Vickers MH, Cognard E, Shepherd PR.

Schizophr Res. 2009 Nov;115(1):30-40. doi: 10.1016/j.schres.2009.07.011. Epub 2009 Aug 12.


Long-term metabolic benefits of exenatide in mice are mediated solely via the known glucagon-like peptide 1 receptor.

Tatarkiewicz K, Sablan EJ, Polizzi CJ, Villescaz C, Parkes DG.

Am J Physiol Regul Integr Comp Physiol. 2014 Apr 1;306(7):R490-8. doi: 10.1152/ajpregu.00495.2013. Epub 2014 Jan 29.


Combination of obesity and high-fat feeding diminishes sensitivity to GLP-1R agonist exendin-4.

Duca FA, Sakar Y, Covasa M.

Diabetes. 2013 Jul;62(7):2410-5. doi: 10.2337/db12-1204. Epub 2013 Feb 19.


Effects of exendin-4 alone and with peptide YY(3-36) on food intake and body weight in diet-induced obese rats.

Reidelberger RD, Haver AC, Apenteng BA, Anders KL, Steenson SM.

Obesity (Silver Spring). 2011 Jan;19(1):121-7. doi: 10.1038/oby.2010.136. Epub 2010 Jun 17.


An albumin-exendin-4 conjugate engages central and peripheral circuits regulating murine energy and glucose homeostasis.

Baggio LL, Huang Q, Cao X, Drucker DJ.

Gastroenterology. 2008 Apr;134(4):1137-47. doi: 10.1053/j.gastro.2008.01.017. Epub 2008 Jan 11.


Comparative effects of the long-acting GLP-1 receptor ligands, liraglutide and exendin-4, on food intake and body weight suppression in rats.

Hayes MR, Kanoski SE, Alhadeff AL, Grill HJ.

Obesity (Silver Spring). 2011 Jul;19(7):1342-9. doi: 10.1038/oby.2011.50. Epub 2011 Mar 17.


Differences in the central anorectic effects of glucagon-like peptide-1 and exendin-4 in rats.

Barrera JG, D'Alessio DA, Drucker DJ, Woods SC, Seeley RJ.

Diabetes. 2009 Dec;58(12):2820-7. doi: 10.2337/db09-0281. Epub 2009 Sep 9.

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