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Items: 1 to 20 of 145

1.

NRF2 plays a protective role in diabetic retinopathy in mice.

Xu Z, Wei Y, Gong J, Cho H, Park JK, Sung ER, Huang H, Wu L, Eberhart C, Handa JT, Du Y, Kern TS, Thimmulappa R, Barber AJ, Biswal S, Duh EJ.

Diabetologia. 2014 Jan;57(1):204-13. doi: 10.1007/s00125-013-3093-8. Epub 2013 Nov 3.

2.

Neuroprotective role of Nrf2 for retinal ganglion cells in ischemia-reperfusion.

Xu Z, Cho H, Hartsock MJ, Mitchell KL, Gong J, Wu L, Wei Y, Wang S, Thimmulappa RK, Sporn MB, Biswal S, Welsbie DS, Duh EJ.

J Neurochem. 2015 Apr;133(2):233-41. doi: 10.1111/jnc.13064. Epub 2015 Mar 4.

3.

Transcription factor Nrf2-mediated antioxidant defense system in the development of diabetic retinopathy.

Zhong Q, Mishra M, Kowluru RA.

Invest Ophthalmol Vis Sci. 2013 Jun 6;54(6):3941-8. doi: 10.1167/iovs.13-11598.

4.

Sigma 1 receptor regulates the oxidative stress response in primary retinal Müller glial cells via NRF2 signaling and system xc(-), the Na(+)-independent glutamate-cystine exchanger.

Wang J, Shanmugam A, Markand S, Zorrilla E, Ganapathy V, Smith SB.

Free Radic Biol Med. 2015 Sep;86:25-36. doi: 10.1016/j.freeradbiomed.2015.04.009. Epub 2015 Apr 25.

PMID:
25920363
5.

α-Melanocyte-stimulating hormone protects retinal vascular endothelial cells from oxidative stress and apoptosis in a rat model of diabetes.

Zhang L, Dong L, Liu X, Jiang Y, Zhang L, Zhang X, Li X, Zhang Y.

PLoS One. 2014 Apr 2;9(4):e93433. doi: 10.1371/journal.pone.0093433. eCollection 2014.

6.

Ischaemia-induced retinal neovascularisation and diabetic retinopathy in mice with conditional knockout of hypoxia-inducible factor-1 in retinal Müller cells.

Lin M, Chen Y, Jin J, Hu Y, Zhou KK, Zhu M, Le YZ, Ge J, Johnson RS, Ma JX.

Diabetologia. 2011 Jun;54(6):1554-66. doi: 10.1007/s00125-011-2081-0. Epub 2011 Mar 1.

PMID:
21360191
7.

Trolox contributes to Nrf2-mediated protection of human and murine primary alveolar type II cells from injury by cigarette smoke.

Messier EM, Bahmed K, Tuder RM, Chu HW, Bowler RP, Kosmider B.

Cell Death Dis. 2013 Apr 4;4:e573. doi: 10.1038/cddis.2013.96.

8.

Nrf2 has a protective role against neuronal and capillary degeneration in retinal ischemia-reperfusion injury.

Wei Y, Gong J, Yoshida T, Eberhart CG, Xu Z, Kombairaju P, Sporn MB, Handa JT, Duh EJ.

Free Radic Biol Med. 2011 Jul 1;51(1):216-24. doi: 10.1016/j.freeradbiomed.2011.04.026. Epub 2011 Apr 19.

9.

Acute exercise stress activates Nrf2/ARE signaling and promotes antioxidant mechanisms in the myocardium.

Muthusamy VR, Kannan S, Sadhaasivam K, Gounder SS, Davidson CJ, Boeheme C, Hoidal JR, Wang L, Rajasekaran NS.

Free Radic Biol Med. 2012 Jan 15;52(2):366-76. doi: 10.1016/j.freeradbiomed.2011.10.440. Epub 2011 Oct 20.

10.

Early modulation of the transcription factor Nrf2 in rodent striatal slices by quinolinic acid, a toxic metabolite of the kynurenine pathway.

Colín-González AL, Luna-López A, Königsberg M, Ali SF, Pedraza-Chaverrí J, Santamaría A.

Neuroscience. 2014 Feb 28;260:130-9. doi: 10.1016/j.neuroscience.2013.12.025. Epub 2013 Dec 19.

PMID:
24361737
11.

Requirement of NOX2 expression in both retina and bone marrow for diabetes-induced retinal vascular injury.

Rojas M, Zhang W, Xu Z, Lemtalsi T, Chandler P, Toque HA, Caldwell RW, Caldwell RB.

PLoS One. 2013 Dec 17;8(12):e84357. doi: 10.1371/journal.pone.0084357. eCollection 2013.

12.

Protective Role of Nuclear Factor E2-Related Factor 2 against Acute Oxidative Stress-Induced Pancreatic β -Cell Damage.

Fu J, Zheng H, Wang H, Yang B, Zhao R, Lu C, Liu Z, Hou Y, Xu Y, Zhang Q, Qu W, Pi J.

Oxid Med Cell Longev. 2015;2015:639191. doi: 10.1155/2015/639191. Epub 2015 Apr 9.

13.

Modulation of Nrf2 expression alters high glucose-induced oxidative stress and antioxidant gene expression in mouse mesangial cells.

Li H, Wang F, Zhang L, Cao Y, Liu W, Hao J, Liu Q, Duan H.

Cell Signal. 2011 Oct;23(10):1625-32. doi: 10.1016/j.cellsig.2011.05.016. Epub 2011 Jun 1.

PMID:
21658446
14.
15.

Protective effects of nuclear factor erythroid 2-related factor 2 on whole body heat stress-induced oxidative damage in the mouse testis.

Li Y, Huang Y, Piao Y, Nagaoka K, Watanabe G, Taya K, Li C.

Reprod Biol Endocrinol. 2013 Mar 21;11:23. doi: 10.1186/1477-7827-11-23.

16.

Role of nuclear factor erythroid 2-related factor 2 in the oxidative stress-dependent hypertension associated with the depletion of DJ-1.

Cuevas S, Yang Y, Konkalmatt P, Asico LD, Feranil J, Jones J, Villar VA, Armando I, Jose PA.

Hypertension. 2015 Jun;65(6):1251-7. doi: 10.1161/HYPERTENSIONAHA.114.04525. Epub 2015 Apr 20.

17.

Mechanisms of Nrf2 protection in astrocytes as identified by quantitative proteomics and siRNA screening.

Dowell JA, Johnson JA.

PLoS One. 2013 Jul 29;8(7):e70163. doi: 10.1371/journal.pone.0070163. Print 2013.

18.

Diabetic downregulation of Nrf2 activity via ERK contributes to oxidative stress-induced insulin resistance in cardiac cells in vitro and in vivo.

Tan Y, Ichikawa T, Li J, Si Q, Yang H, Chen X, Goldblatt CS, Meyer CJ, Li X, Cai L, Cui T.

Diabetes. 2011 Feb;60(2):625-33. doi: 10.2337/db10-1164.

19.

The protective role of Nrf2 in streptozotocin-induced diabetic nephropathy.

Jiang T, Huang Z, Lin Y, Zhang Z, Fang D, Zhang DD.

Diabetes. 2010 Apr;59(4):850-60. doi: 10.2337/db09-1342. Epub 2010 Jan 26.

20.

A novel small molecule, N-(4-(2-pyridyl)(1,3-thiazol-2-yl))-2-(2,4,6-trimethylphenoxy) acetamide, selectively protects against oxidative stress-induced cell death by activating the Nrf2-ARE pathway: therapeutic implications for ALS.

Kanno T, Tanaka K, Yanagisawa Y, Yasutake K, Hadano S, Yoshii F, Hirayama N, Ikeda JE.

Free Radic Biol Med. 2012 Dec 1;53(11):2028-42. doi: 10.1016/j.freeradbiomed.2012.09.010. Epub 2012 Sep 20.

PMID:
23000247
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