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Items: 1 to 20 of 239

1.

Structural characterization of in vitro metabolites of the new anticancer agent EAPB0503 by liquid chromatography-tandem mass spectrometry.

Lafaille F, Solassol I, Enjalbal C, Bertrand B, Doulain PE, Vappiani J, Bonnet PA, Deleuze-Masquéfa C, Bressolle FM.

J Pharm Biomed Anal. 2014 Jan;88:429-40. doi: 10.1016/j.jpba.2013.09.015. Epub 2013 Oct 5.

PMID:
24176748
2.

Characterization of a new anticancer agent, EAPB0203, and its main metabolites: nuclear magnetic resonance and liquid chromatography-mass spectrometry studies.

Lafaille F, Banaigs B, Inguimbert N, Enjalbal C, Doulain PE, Bonnet PA, Masquefa C, Bressolle FM.

Anal Chem. 2012 Nov 20;84(22):9865-72. doi: 10.1021/ac3021483. Epub 2012 Oct 31.

PMID:
23072539
4.

In vivo metabolic investigation of moxifloxacin using liquid chromatography/electrospray ionization tandem mass spectrometry in combination with online hydrogen/deuterium exchange experiments.

Raju B, Ramesh M, Borkar RM, Srinivas R, Padiya R, Banerjee SK.

Rapid Commun Mass Spectrom. 2012 Aug 30;26(16):1817-31. doi: 10.1002/rcm.6288.

PMID:
22777784
5.

Structural elucidation of in vitro metabolites of emodin by liquid chromatography-tandem mass spectrometry.

Song R, Xu F, Zhang Z, Liu Y, Dong H, Tian Y.

Biomed Chromatogr. 2008 Nov;22(11):1230-6. doi: 10.1002/bmc.1050.

PMID:
18651591
6.

Metabolism and pharmacokinetics of EAPB0203 and EAPB0503, two imidazoquinoxaline compounds previously shown to have antitumoral activity on melanoma and T-lymphomas.

Khier S, Gattacceca F, El Messaoudi S, Lafaille F, Deleuze-Masquéfa C, Bompart J, Cooper JF, Solassol I, Pinguet F, Bonnet PA, Bressolle FM.

Drug Metab Dispos. 2010 Oct;38(10):1836-47. doi: 10.1124/dmd.110.034579. Epub 2010 Jul 21.

7.

Quantitation of imidazo[1,2-a]quinoxaline derivatives in human and rat plasma using LC/ESI-MS.

Khier S, Moarbess G, Deleuze-Masquefa C, Solassol I, Margout D, Pinguet F, Bonnet PA, Bressolle FM.

J Sep Sci. 2009 May;32(9):1363-73. doi: 10.1002/jssc.200800668.

PMID:
19399864
8.

Metabolite identification of a new tyrosine kinase inhibitor, HM781-36B, and a pharmacokinetic study by liquid chromatography/tandem mass spectrometry.

Kim E, Kim H, Suh K, Kwon S, Lee G, Park NH, Hong J.

Rapid Commun Mass Spectrom. 2013 Jun 15;27(11):1183-95. doi: 10.1002/rcm.6559.

PMID:
23650031
9.

Identification and structural characterization of in vivo metabolites of ketorolac using liquid chromatography electrospray ionization tandem mass spectrometry (LC/ESI-MS/MS).

Raju B, Ramesh M, Borkar RM, Padiya R, Banerjee SK, Srinivas R.

J Mass Spectrom. 2012 Jul;47(7):919-31. doi: 10.1002/jms.3043.

PMID:
22791260
11.

Metabolism of olaquindox in rat liver microsomes: structural elucidation of metabolites by high-performance liquid chromatography combined with ion trap/time-of-flight mass spectrometry.

Liu Z, Huang L, Dai M, Chen D, Wang Y, Tao Y, Yuan Z.

Rapid Commun Mass Spectrom. 2008 Apr;22(7):1009-16. doi: 10.1002/rcm.3422.

PMID:
18320546
13.

Identification of the metabolites of ecabet bismuth in rat bile by liquid chromatography-electrospray ionization-tandem mass spectrometry.

Wu Y, Yang J, Ding L, Xu G, Qian W, Yun C, He J.

Eur J Mass Spectrom (Chichester, Eng). 2009;15(4):531-9. doi: 10.1255/ejms.1006.

PMID:
19661561
14.
15.

Analysis of furo[3,2-c]tetrahydroquinoline and pyrano[3,2-c]tetrahydroquinoline derivatives as antitumor agents and their metabolites by liquid chromatography/electrospray ionization tandem mass spectrometry.

Hou X, Luo H, Zhong H, Wu F, Zhou M, Zhang W, Han X, Yan G, Zhang M, Lu L, Ding Z, He G, Li R.

Rapid Commun Mass Spectrom. 2013 Jun 15;27(11):1222-30. doi: 10.1002/rcm.6562.

PMID:
23650035
16.

Application of electrospray ionization hybrid ion trap/time-of-flight mass spectrometry in the rapid characterization of quinocetone metabolites formed in vitro.

Liu ZY, Huang LL, Chen DM, Dai MH, Tao YF, Wang YL, Yuan ZH.

Anal Bioanal Chem. 2010 Feb;396(3):1259-71. doi: 10.1007/s00216-009-3245-3. Epub 2009 Dec 18.

PMID:
20020112
18.

Identification of in vivo and in vitro metabolites of triptolide by liquid chromatography-tandem mass spectrometry.

Peng ZH, Wang JJ, Du P, Chen Y.

J Pharm Biomed Anal. 2012 Nov;70:624-30. doi: 10.1016/j.jpba.2012.06.026. Epub 2012 Jun 30.

PMID:
22824635
19.

Characterization of in vitro metabolites of TM-2, a potential antitumor drug, in rat, dog and human liver microsomes using liquid chromatography/tandem mass spectrometry.

Men L, Zhao Y, Lin H, Yang M, Liu H, Tang X, Yu Z.

Rapid Commun Mass Spectrom. 2014 Oct 30;28(20):2162-70. doi: 10.1002/rcm.7003.

PMID:
25178720
20.

Characterization of the Phase II metabolites of rutaecarpine in rat by liquid chromatography-electrospray ionization-tandem mass spectrometry.

Lee SK, Lee DW, Jeon TW, Jin CH, Kim GH, Jun IH, Lee DJ, Kim SI, Kim DH, Jahng Y, Jeong TC.

Xenobiotica. 2005 Dec;35(12):1135-45.

PMID:
16418066
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