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Results: 1 to 20 of 98

1.

Endocytic profiles of δ-opioid receptor ligands determine the duration of rapid but not sustained cAMP responses.

Tudashki HB, Robertson DN, Schiller PW, Pineyro G.

Mol Pharmacol. 2014 Jan;85(1):148-61. doi: 10.1124/mol.113.089003. Epub 2013 Oct 30.

PMID:
24174495
[PubMed - indexed for MEDLINE]
2.

Evidence for a selective role of the delta-opioid agonist [8R-(4bS*,8aalpha,8abeta, 12bbeta)]7,10-Dimethyl-1-methoxy-11-(2-methylpropyl)oxycarbonyl 5,6,7,8,12,12b-hexahydro-(9H)-4,8-methanobenzofuro[3,2-e]pyrrolo[2,3-g]isoquinoline hydrochloride (SB-235863) in blocking hyperalgesia associated with inflammatory and neuropathic pain responses.

Petrillo P, Angelici O, Bingham S, Ficalora G, Garnier M, Zaratin PF, Petrone G, Pozzi O, Sbacchi M, Stean TO, Upton N, Dondio GM, Scheideler MA.

J Pharmacol Exp Ther. 2003 Dec;307(3):1079-89. Epub 2003 Oct 9.

PMID:
14551288
[PubMed - indexed for MEDLINE]
Free Article
3.

Ligand- and cell-dependent determinants of internalization and cAMP modulation by delta opioid receptor (DOR) agonists.

Charfi I, Nagi K, Mnie-Filali O, Thibault D, Balboni G, Schiller PW, Trudeau LE, Pineyro G.

Cell Mol Life Sci. 2014 Apr;71(8):1529-46.

PMID:
24022593
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Reciprocal regulation of agonist and inverse agonist signaling efficacy upon short-term treatment of the human delta-opioid receptor with an inverse agonist.

Piñeyro G, Azzi M, deLéan A, Schiller PW, Bouvier M.

Mol Pharmacol. 2005 Jan;67(1):336-48. Epub 2004 Oct 20.

PMID:
15496503
[PubMed - indexed for MEDLINE]
Free Article
5.
6.

Ligand-directed trafficking of the δ-opioid receptor in vivo: two paths toward analgesic tolerance.

Pradhan AA, Walwyn W, Nozaki C, Filliol D, Erbs E, Matifas A, Evans C, Kieffer BL.

J Neurosci. 2010 Dec 8;30(49):16459-68. doi: 10.1523/JNEUROSCI.3748-10.2010.

PMID:
21147985
[PubMed - indexed for MEDLINE]
Free PMC Article
7.
8.

Internalization and Src activity regulate the time course of ERK activation by delta opioid receptor ligands.

Audet N, Paquin-Gobeil M, Landry-Paquet O, Schiller PW, Piñeyro G.

J Biol Chem. 2005 Mar 4;280(9):7808-16. Epub 2005 Jan 4.

PMID:
15632168
[PubMed - indexed for MEDLINE]
Free Article
9.

Opioid regulation of the mouse delta-opioid receptor expressed in human embryonic kidney 293 cells.

Bot G, Blake AD, Li S, Reisine T.

Mol Pharmacol. 1997 Aug;52(2):272-81.

PMID:
9271350
[PubMed - indexed for MEDLINE]
Free Article
10.

De novo design, synthesis, and biological activities of high-affinity and selective non-peptide agonists of the delta-opioid receptor.

Liao S, Alfaro-Lopez J, Shenderovich MD, Hosohata K, Lin J, Li X, Stropova D, Davis P, Jernigan KA, Porreca F, Yamamura HI, Hruby VJ.

J Med Chem. 1998 Nov 19;41(24):4767-76.

PMID:
9822547
[PubMed - indexed for MEDLINE]
11.

delta-Opioid receptor agonists produce antinociception and [35S]GTPgammaS binding in mu receptor knockout mice.

Hosohata Y, Vanderah TW, Burkey TH, Ossipov MH, Kovelowski CJ, Sora I, Uhl GR, Zhang X, Rice KC, Roeske WR, Hruby VJ, Yamamura HI, Lai J, Porreca F.

Eur J Pharmacol. 2000 Feb 4;388(3):241-8.

PMID:
10675732
[PubMed - indexed for MEDLINE]
12.

Modulation of μ-opioid receptor signaling by RGS19 in SH-SY5Y cells.

Wang Q, Traynor JR.

Mol Pharmacol. 2013 Feb;83(2):512-20. doi: 10.1124/mol.112.081992. Epub 2012 Nov 29.

PMID:
23197645
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Differential association of receptor-Gβγ complexes with β-arrestin2 determines recycling bias and potential for tolerance of δ opioid receptor agonists.

Audet N, Charfi I, Mnie-Filali O, Amraei M, Chabot-Doré AJ, Millecamps M, Stone LS, Pineyro G.

J Neurosci. 2012 Apr 4;32(14):4827-40. doi: 10.1523/JNEUROSCI.3734-11.2012.

PMID:
22492038
[PubMed - indexed for MEDLINE]
Free Article
14.

Agonist-specific down-regulation of the human delta-opioid receptor.

Okura T, Varga EV, Hosohata Y, Navratilova E, Cowell SM, Rice K, Nagase H, Hruby VJ, Roeske WR, Yamamura HI.

Eur J Pharmacol. 2003 Jan 10;459(1):9-16.

PMID:
12505529
[PubMed - indexed for MEDLINE]
16.

Delta-opioid ligands reverse alfentanil-induced respiratory depression but not antinociception.

Su YF, McNutt RW, Chang KJ.

J Pharmacol Exp Ther. 1998 Dec;287(3):815-23.

PMID:
9864259
[PubMed - indexed for MEDLINE]
Free Article
17.

Post-endocytic fates of delta-opioid receptor are regulated by GRK2-mediated receptor phosphorylation and distinct beta-arrestin isoforms.

Zhang X, Wang F, Chen X, Chen Y, Ma L.

J Neurochem. 2008 Jul;106(2):781-92. doi: 10.1111/j.1471-4159.2008.05431.x. Epub 2008 Apr 17.

PMID:
18419762
[PubMed - indexed for MEDLINE]
18.

Functional interaction among opioid receptor types: up-regulation of mu- and delta-opioid receptor functions after repeated stimulation of kappa-opioid receptors.

Khotib J, Narita M, Suzuki M, Yajima Y, Suzuki T.

Neuropharmacology. 2004 Mar;46(4):531-40.

PMID:
14975677
[PubMed - indexed for MEDLINE]
19.
20.

Relationship between rate and extent of G protein activation: comparison between full and partial opioid agonists.

Traynor JR, Clark MJ, Remmers AE.

J Pharmacol Exp Ther. 2002 Jan;300(1):157-61.

PMID:
11752111
[PubMed - indexed for MEDLINE]
Free Article

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