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Items: 1 to 20 of 114

1.

Merlin sumoylation is required for its tumor suppressor activity.

Qi Q, Liu X, Brat DJ, Ye K.

Oncogene. 2014 Oct 9;33(41):4893-903. doi: 10.1038/onc.2013.438. Epub 2013 Oct 28.

PMID:
24166499
2.

Akt phosphorylation regulates the tumour-suppressor merlin through ubiquitination and degradation.

Tang X, Jang SW, Wang X, Liu Z, Bahr SM, Sun SY, Brat D, Gutmann DH, Ye K.

Nat Cell Biol. 2007 Oct;9(10):1199-207. Epub 2007 Sep 23.

PMID:
17891137
3.

Phosphorylation of merlin regulates its stability and tumor suppressive activity.

Ye K.

Cell Adh Migr. 2007 Oct-Dec;1(4):196-8. Epub 2007 Oct 22. Review.

4.

Protein kinase A-mediated phosphorylation of the NF2 tumor suppressor protein merlin at serine 10 affects the actin cytoskeleton.

Laulajainen M, Muranen T, Carpén O, Grönholm M.

Oncogene. 2008 May 22;27(23):3233-43. Epub 2007 Dec 10.

PMID:
18071304
5.

NF2/merlin is a novel negative regulator of mTOR complex 1, and activation of mTORC1 is associated with meningioma and schwannoma growth.

James MF, Han S, Polizzano C, Plotkin SR, Manning BD, Stemmer-Rachamimov AO, Gusella JF, Ramesh V.

Mol Cell Biol. 2009 Aug;29(15):4250-61. doi: 10.1128/MCB.01581-08. Epub 2009 May 18.

6.

Evolution and origin of merlin, the product of the Neurofibromatosis type 2 (NF2) tumor-suppressor gene.

Golovnina K, Blinov A, Akhmametyeva EM, Omelyanchuk LV, Chang LS.

BMC Evol Biol. 2005 Dec 2;5:69.

7.

Cell cycle-dependent nucleocytoplasmic shuttling of the neurofibromatosis 2 tumour suppressor merlin.

Muranen T, Grönholm M, Renkema GH, Carpén O.

Oncogene. 2005 Feb 10;24(7):1150-8.

PMID:
15580288
8.

Akt phosphorylation of merlin enhances its binding to phosphatidylinositols and inhibits the tumor-suppressive activities of merlin.

Okada M, Wang Y, Jang SW, Tang X, Neri LM, Ye K.

Cancer Res. 2009 May 1;69(9):4043-51. doi: 10.1158/0008-5472.CAN-08-3931. Epub 2009 Apr 7.

9.
10.

Shedding light on Merlin's wizardry.

Okada T, You L, Giancotti FG.

Trends Cell Biol. 2007 May;17(5):222-9. Epub 2007 Apr 17. Review. Erratum in: Trends Cell Biol. 2008 Jan;18(1):11.

PMID:
17442573
11.

Erbin and the NF2 tumor suppressor Merlin cooperatively regulate cell-type-specific activation of PAK2 by TGF-beta.

Wilkes MC, Repellin CE, Hong M, Bracamonte M, Penheiter SG, Borg JP, Leof EB.

Dev Cell. 2009 Mar;16(3):433-44. doi: 10.1016/j.devcel.2009.01.009.

12.

Inactivation of the NF2 tumor suppressor protein merlin in DU145 prostate cancer cells.

Horiguchi A, Zheng R, Shen R, Nanus DM.

Prostate. 2008 Jun 15;68(9):975-84. doi: 10.1002/pros.20760.

PMID:
18361411
13.

The NF2 tumor suppressor regulates microtubule-based vesicle trafficking via a novel Rac, MLK and p38(SAPK) pathway.

Hennigan RF, Moon CA, Parysek LM, Monk KR, Morfini G, Berth S, Brady S, Ratner N.

Oncogene. 2013 Feb 28;32(9):1135-43. doi: 10.1038/onc.2012.135. Epub 2012 Apr 23.

15.

Tumorigenic transformation by CPI-17 through inhibition of a merlin phosphatase.

Jin H, Sperka T, Herrlich P, Morrison H.

Nature. 2006 Aug 3;442(7102):576-9.

PMID:
16885985
16.

Merlin phosphorylation by p21-activated kinase 2 and effects of phosphorylation on merlin localization.

Kissil JL, Johnson KC, Eckman MS, Jacks T.

J Biol Chem. 2002 Mar 22;277(12):10394-9. Epub 2002 Jan 8.

17.

Molecular insights into NF2/Merlin tumor suppressor function.

Cooper J, Giancotti FG.

FEBS Lett. 2014 Aug 19;588(16):2743-52. doi: 10.1016/j.febslet.2014.04.001. Epub 2014 Apr 12. Review.

18.

The Nf2 tumor suppressor, merlin, functions in Rac-dependent signaling.

Shaw RJ, Paez JG, Curto M, Yaktine A, Pruitt WM, Saotome I, O'Bryan JP, Gupta V, Ratner N, Der CJ, Jacks T, McClatchey AI.

Dev Cell. 2001 Jul;1(1):63-72.

19.

Merlin, the NF2 gene product.

Pećina-Šlaus N.

Pathol Oncol Res. 2013 Jul;19(3):365-73. doi: 10.1007/s12253-013-9644-y. Epub 2013 May 12. Review.

PMID:
23666797
20.

p21-activated kinase links Rac/Cdc42 signaling to merlin.

Xiao GH, Beeser A, Chernoff J, Testa JR.

J Biol Chem. 2002 Jan 11;277(2):883-6. Epub 2001 Nov 21.

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