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Results: 1 to 20 of 101

1.

Exogenous cannabinoids as substrates, inhibitors, and inducers of human drug metabolizing enzymes: a systematic review.

Stout SM, Cimino NM.

Drug Metab Rev. 2014 Feb;46(1):86-95. doi: 10.3109/03602532.2013.849268. Epub 2013 Oct 25.

PMID:
24160757
[PubMed - in process]
2.

Comparison in the in vitro inhibitory effects of major phytocannabinoids and polycyclic aromatic hydrocarbons contained in marijuana smoke on cytochrome P450 2C9 activity.

Yamaori S, Koeda K, Kushihara M, Hada Y, Yamamoto I, Watanabe K.

Drug Metab Pharmacokinet. 2012;27(3):294-300. Epub 2011 Dec 13.

PMID:
22166891
[PubMed - indexed for MEDLINE]
Free Article
3.

Can oral fluid cannabinoid testing monitor medication compliance and/or cannabis smoking during oral THC and oromucosal Sativex administration?

Lee D, Karschner EL, Milman G, Barnes AJ, Goodwin RS, Huestis MA.

Drug Alcohol Depend. 2013 Jun 1;130(1-3):68-76. doi: 10.1016/j.drugalcdep.2012.10.011. Epub 2012 Nov 10.

PMID:
23146820
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Contribution of human cytochrome p-450 isoforms to the metabolism of the simplest phenothiazine neuroleptic promazine.

Wójcikowski J, Pichard-Garcia L, Maurel P, Daniel WA.

Br J Pharmacol. 2003 Apr;138(8):1465-74.

PMID:
12721102
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Characterization of human hepatic and extrahepatic UDP-glucuronosyltransferase enzymes involved in the metabolism of classic cannabinoids.

Mazur A, Lichti CF, Prather PL, Zielinska AK, Bratton SM, Gallus-Zawada A, Finel M, Miller GP, Radomińska-Pandya A, Moran JH.

Drug Metab Dispos. 2009 Jul;37(7):1496-504. doi: 10.1124/dmd.109.026898. Epub 2009 Apr 1.

PMID:
19339377
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Characterization of major phytocannabinoids, cannabidiol and cannabinol, as isoform-selective and potent inhibitors of human CYP1 enzymes.

Yamaori S, Kushihara M, Yamamoto I, Watanabe K.

Biochem Pharmacol. 2010 Jun 1;79(11):1691-8. doi: 10.1016/j.bcp.2010.01.028. Epub 2010 Feb 1.

PMID:
20117100
[PubMed - indexed for MEDLINE]
8.

Simultaneous and sensitive analysis of THC, 11-OH-THC, THC-COOH, CBD, and CBN by GC-MS in plasma after oral application of small doses of THC and cannabis extract.

Nadulski T, Sporkert F, Schnelle M, Stadelmann AM, Roser P, Schefter T, Pragst F.

J Anal Toxicol. 2005 Nov-Dec;29(8):782-9.

PMID:
16356335
[PubMed - indexed for MEDLINE]
Free Article
9.

Oral fluid cannabinoids in chronic, daily Cannabis smokers during sustained, monitored abstinence.

Lee D, Milman G, Barnes AJ, Goodwin RS, Hirvonen J, Huestis MA.

Clin Chem. 2011 Aug;57(8):1127-36. doi: 10.1373/clinchem.2011.164822. Epub 2011 Jun 15.

PMID:
21677094
[PubMed - indexed for MEDLINE]
Free Article
10.

Cytochrome P450 enzymes involved in the metabolism of tetrahydrocannabinols and cannabinol by human hepatic microsomes.

Watanabe K, Yamaori S, Funahashi T, Kimura T, Yamamoto I.

Life Sci. 2007 Mar 20;80(15):1415-9. Epub 2007 Jan 17.

PMID:
17303175
[PubMed - indexed for MEDLINE]
11.

Early cannabinoid exposure influences neuroendocrine and reproductive functions in mice: II. Postnatal effects.

Dalterio S, Steger R, Mayfield D, Bartke A.

Pharmacol Biochem Behav. 1984 Jan;20(1):115-23.

PMID:
6320228
[PubMed - indexed for MEDLINE]
12.

Identification of recent cannabis use: whole-blood and plasma free and glucuronidated cannabinoid pharmacokinetics following controlled smoked cannabis administration.

Schwope DM, Karschner EL, Gorelick DA, Huestis MA.

Clin Chem. 2011 Oct;57(10):1406-14. doi: 10.1373/clinchem.2011.171777. Epub 2011 Aug 11.

PMID:
21836075
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

CYP3A4 is a major isoform responsible for oxidation of 7-hydroxy-Delta(8)-tetrahydrocannabinol to 7-oxo-delta(8)-tetrahydrocannabinol in human liver microsomes.

Matsunaga T, Kishi N, Higuchi S, Watanabe K, Ohshima T, Yamamoto I.

Drug Metab Dispos. 2000 Nov;28(11):1291-6.

PMID:
11038155
[PubMed - indexed for MEDLINE]
Free Article
14.

Human skin permeation of Delta8-tetrahydrocannabinol, cannabidiol and cannabinol.

Stinchcomb AL, Valiveti S, Hammell DC, Ramsey DR.

J Pharm Pharmacol. 2004 Mar;56(3):291-7.

PMID:
15025853
[PubMed - indexed for MEDLINE]
15.

Characterization of P-glycoprotein inhibition by major cannabinoids from marijuana.

Zhu HJ, Wang JS, Markowitz JS, Donovan JL, Gibson BB, Gefroh HA, Devane CL.

J Pharmacol Exp Ther. 2006 May;317(2):850-7. Epub 2006 Jan 26.

PMID:
16439618
[PubMed - indexed for MEDLINE]
Free Article
16.

The properties of UDP-glucuronyltransferase for cannabinoids in rat liver microsomes.

Watanabe K, Kita M, Yamamoto I, Oguri K, Yoshimura H.

J Pharmacobiodyn. 1983 Aug;6(8):581-7.

PMID:
6315914
[PubMed - indexed for MEDLINE]
17.

Cannabinoid disposition in oral fluid after controlled smoked cannabis.

Lee D, Schwope DM, Milman G, Barnes AJ, Gorelick DA, Huestis MA.

Clin Chem. 2012 Apr;58(4):748-56. doi: 10.1373/clinchem.2011.177881. Epub 2012 Jan 24.

PMID:
22273566
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Identification of the human liver cytochrome P450 isoenzymes responsible for the 5-methylhydroxylation of the novel anti-fibrotic drug AKF-PD.

He X, Luo X, Liu Z, Hu G, Cheng Z.

Xenobiotica. 2011 Oct;41(10):844-50. doi: 10.3109/00498254.2011.589480. Epub 2011 Jun 16.

PMID:
21679010
[PubMed - indexed for MEDLINE]
19.

Effects of cannabinoids and cannabinoid-enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes.

De Petrocellis L, Ligresti A, Moriello AS, Allarà M, Bisogno T, Petrosino S, Stott CG, Di Marzo V.

Br J Pharmacol. 2011 Aug;163(7):1479-94. doi: 10.1111/j.1476-5381.2010.01166.x.

PMID:
21175579
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Analysis of cannabis seizures in NSW, Australia: cannabis potency and cannabinoid profile.

Swift W, Wong A, Li KM, Arnold JC, McGregor IS.

PLoS One. 2013 Jul 24;8(7):e70052. doi: 10.1371/journal.pone.0070052. Print 2013.

PMID:
23894589
[PubMed - indexed for MEDLINE]
Free PMC Article

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