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Results: 1 to 20 of 94

1.

Implication of transcriptional repression in compound C-induced apoptosis in cancer cells.

Dai RY, Zhao XF, Li JJ, Chen R, Luo ZL, Yu LX, Chen SK, Zhang CY, Duan CY, Liu YP, Feng CH, Xia XM, Li H, Fu J, Wang HY.

Cell Death Dis. 2013 Oct 24;4:e883. doi: 10.1038/cddis.2013.419.

PMID:
24157877
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Phosphorylation of eIF2α attenuates statin-induced apoptosis by inhibiting the stabilization and translocation of p53 to the mitochondria.

Lee SK, Kim YS.

Int J Oncol. 2013 Mar;42(3):810-6. doi: 10.3892/ijo.2013.1792. Epub 2013 Jan 23.

PMID:
23354132
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Andrographolide sensitizes cancer cells to TRAIL-induced apoptosis via p53-mediated death receptor 4 up-regulation.

Zhou J, Lu GD, Ong CS, Ong CN, Shen HM.

Mol Cancer Ther. 2008 Jul;7(7):2170-80. doi: 10.1158/1535-7163.MCT-08-0071.

PMID:
18645026
[PubMed - indexed for MEDLINE]
Free Article
4.

p53 modulates the AMPK inhibitor compound C induced apoptosis in human skin cancer cells.

Huang SW, Wu CY, Wang YT, Kao JK, Lin CC, Chang CC, Mu SW, Chen YY, Chiu HW, Chang CH, Liang SM, Chen YJ, Huang JL, Shieh JJ.

Toxicol Appl Pharmacol. 2013 Feb 15;267(1):113-24. doi: 10.1016/j.taap.2012.12.016. Epub 2012 Dec 27.

PMID:
23274516
[PubMed - indexed for MEDLINE]
5.

Compound C induces protective autophagy in cancer cells through AMPK inhibition-independent blockade of Akt/mTOR pathway.

Vucicevic L, Misirkic M, Janjetovic K, Vilimanovich U, Sudar E, Isenovic E, Prica M, Harhaji-Trajkovic L, Kravic-Stevovic T, Bumbasirevic V, Trajkovic V.

Autophagy. 2011 Jan;7(1):40-50. Epub 2011 Jan 1.

PMID:
20980833
[PubMed - indexed for MEDLINE]
Free Article
6.

Compound C sensitizes Caki renal cancer cells to TRAIL-induced apoptosis through reactive oxygen species-mediated down-regulation of c-FLIPL and Mcl-1.

Jang JH, Lee TJ, Yang ES, Min do S, Kim YH, Kim SH, Choi YH, Park JW, Choi KS, Kwon TK.

Exp Cell Res. 2010 Aug 1;316(13):2194-203. doi: 10.1016/j.yexcr.2010.04.028. Epub 2010 May 6.

PMID:
20451517
[PubMed - indexed for MEDLINE]
7.

AMP-activated protein kinase-dependent and -independent mechanisms underlying in vitro antiglioma action of compound C.

Vucicevic L, Misirkic M, Janjetovic K, Harhaji-Trajkovic L, Prica M, Stevanovic D, Isenovic E, Sudar E, Sumarac-Dumanovic M, Micic D, Trajkovic V.

Biochem Pharmacol. 2009 Jun 1;77(11):1684-93. doi: 10.1016/j.bcp.2009.03.005. Epub 2009 Mar 14.

PMID:
19428322
[PubMed - indexed for MEDLINE]
8.

A novel transcriptional inhibitor induces apoptosis in tumor cells and exhibits antiangiogenic activity.

Radhakrishnan SK, Gartel AL.

Cancer Res. 2006 Mar 15;66(6):3264-70.

PMID:
16540679
[PubMed - indexed for MEDLINE]
Free Article
9.

Arsenic trioxide induces apoptosis in NB-4, an acute promyelocytic leukemia cell line, through up-regulation of p73 via suppression of nuclear factor kappa B-mediated inhibition of p73 transcription and prevention of NF-kappaB-mediated induction of XIAP, cIAP2, BCL-XL and survivin.

Momeny M, Zakidizaji M, Ghasemi R, Dehpour AR, Rahimi-Balaei M, Abdolazimi Y, Ghavamzadeh A, Alimoghaddam K, Ghaffari SH.

Med Oncol. 2010 Sep;27(3):833-42. doi: 10.1007/s12032-009-9294-9. Epub 2009 Sep 10.

PMID:
19763917
[PubMed - indexed for MEDLINE]
10.

p14(ARF)-induced apoptosis in p53 protein-deficient cells is mediated by BH3-only protein-independent derepression of Bak protein through down-regulation of Mcl-1 and Bcl-xL proteins.

Müer A, Overkamp T, Gillissen B, Richter A, Pretzsch T, Milojkovic A, Dörken B, Daniel PT, Hemmati P.

J Biol Chem. 2012 May 18;287(21):17343-52. doi: 10.1074/jbc.M111.314898. Epub 2012 Feb 21.

PMID:
22354970
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Penta-1,2,3,4,6-O-galloyl-beta-D-glucose induces p53 and inhibits STAT3 in prostate cancer cells in vitro and suppresses prostate xenograft tumor growth in vivo.

Hu H, Lee HJ, Jiang C, Zhang J, Wang L, Zhao Y, Xiang Q, Lee EO, Kim SH, Lü J.

Mol Cancer Ther. 2008 Sep;7(9):2681-91. doi: 10.1158/1535-7163.MCT-08-0456. Erratum in: Mol Cancer Ther. 2008 Nov;7(11):3654.

PMID:
18790750
[PubMed - indexed for MEDLINE]
Free Article
12.

Wip1 sensitizes p53-negative tumors to apoptosis by regulating the Bax/Bcl-xL ratio.

Goloudina AR, Mazur SJ, Appella E, Garrido C, Demidov ON.

Cell Cycle. 2012 May 15;11(10):1883-7. doi: 10.4161/cc.19901. Epub 2012 May 15.

PMID:
22544321
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

B1-induced caspase-independent apoptosis in MCF-7 cells is mediated by down-regulation of Bcl-2 via p53 binding to P2 promoter TATA box.

Liang X, Xu K, Xu Y, Liu J, Qian X.

Toxicol Appl Pharmacol. 2011 Oct 1;256(1):52-61. doi: 10.1016/j.taap.2011.07.010. Epub 2011 Jul 23.

PMID:
21821060
[PubMed - indexed for MEDLINE]
14.

The p53 upregulated modulator of apoptosis (PUMA) chemosensitizes intrinsically resistant ovarian cancer cells to cisplatin by lowering the threshold set by Bcl-x(L) and Mcl-1.

Yuan Z, Cao K, Lin C, Li L, Liu HY, Zhao XY, Liu L, Deng HX, Li J, Nie CL, Wei YQ.

Mol Med. 2011;17(11-12):1262-74. doi: 10.2119/molmed.2011.00176. Epub 2011 Aug 19.

PMID:
21863213
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

AMPK inhibitor compound C suppresses cell proliferation by induction of apoptosis and autophagy in human colorectal cancer cells.

Yang WL, Perillo W, Liou D, Marambaud P, Wang P.

J Surg Oncol. 2012 Nov;106(6):680-8. doi: 10.1002/jso.23184. Epub 2012 Jun 4.

PMID:
22674626
[PubMed - indexed for MEDLINE]
16.

Regulation of PUMA-alpha by p53 in cisplatin-induced renal cell apoptosis.

Jiang M, Wei Q, Wang J, Du Q, Yu J, Zhang L, Dong Z.

Oncogene. 2006 Jul 6;25(29):4056-66. Epub 2006 Feb 20.

PMID:
16491117
[PubMed - indexed for MEDLINE]
17.

CP-31398 restores mutant p53 tumor suppressor function and inhibits UVB-induced skin carcinogenesis in mice.

Tang X, Zhu Y, Han L, Kim AL, Kopelovich L, Bickers DR, Athar M.

J Clin Invest. 2007 Dec;117(12):3753-64.

PMID:
18060030
[PubMed - indexed for MEDLINE]
Free PMC Article
18.
19.

Overexpression of BLCAP induces S phase arrest and apoptosis independent of p53 and NF-kappaB in human tongue carcinoma : BLCAP overexpression induces S phase arrest and apoptosis.

Yao J, Duan L, Fan M, Yuan J, Wu X.

Mol Cell Biochem. 2007 Mar;297(1-2):81-92. Epub 2006 Oct 10.

PMID:
17031575
[PubMed - indexed for MEDLINE]
20.

Arsenic trioxide down-regulates antiapoptotic genes and induces cell death in mycosis fungoides tumors in a mouse model.

Tun-Kyi A, Qin JZ, Oberholzer PA, Navarini AA, Hassel JC, Dummer R, Döbbeling U.

Ann Oncol. 2008 Aug;19(8):1488-94. doi: 10.1093/annonc/mdn056. Epub 2008 Mar 17.

PMID:
18349030
[PubMed - indexed for MEDLINE]
Free Article

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