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Results: 1 to 20 of 109

1.

Drug discovery and human African trypanosomiasis: a disease less neglected?

Ferrins L, Rahmani R, Baell JB.

Future Med Chem. 2013 Oct;5(15):1801-41. doi: 10.4155/fmc.13.162. Review.

PMID:
24144414
[PubMed - indexed for MEDLINE]
2.

Do we need new drugs against human African trypanosomiasis?

Stich A, Ponte-Sucre A, Holzgrabe U.

Lancet Infect Dis. 2013 Sep;13(9):733-4. doi: 10.1016/S1473-3099(13)70191-9. No abstract available.

PMID:
23969207
[PubMed - indexed for MEDLINE]
3.

Current chemotherapy of human African trypanosomiasis.

Docampo R, Moreno SN.

Parasitol Res. 2003 Jun;90 Supp 1:S10-3. Epub 2002 Nov 23. Review.

PMID:
12811544
[PubMed - indexed for MEDLINE]
4.

Potential new drugs for human African trypanosomiasis: some progress at last.

Barrett MP.

Curr Opin Infect Dis. 2010 Dec;23(6):603-8. doi: 10.1097/QCO.0b013e32833f9fd0. Review.

PMID:
20844428
[PubMed - indexed for MEDLINE]
5.

Drug resistance in human African trypanosomiasis.

Barrett MP, Vincent IM, Burchmore RJ, Kazibwe AJ, Matovu E.

Future Microbiol. 2011 Sep;6(9):1037-47. doi: 10.2217/fmb.11.88. Review.

PMID:
21958143
[PubMed - indexed for MEDLINE]
6.

Nifurtimox-eflornithine combination therapy for second-stage African Trypanosoma brucei gambiense trypanosomiasis: a multicentre, randomised, phase III, non-inferiority trial.

Priotto G, Kasparian S, Mutombo W, Ngouama D, Ghorashian S, Arnold U, Ghabri S, Baudin E, Buard V, Kazadi-Kyanza S, Ilunga M, Mutangala W, Pohlig G, Schmid C, Karunakara U, Torreele E, Kande V.

Lancet. 2009 Jul 4;374(9683):56-64. doi: 10.1016/S0140-6736(09)61117-X. Epub 2009 Jun 24.

PMID:
19559476
[PubMed - indexed for MEDLINE]
7.

Human African trypanosomiasis: pharmacological re-engagement with a neglected disease.

Barrett MP, Boykin DW, Brun R, Tidwell RR.

Br J Pharmacol. 2007 Dec;152(8):1155-71. Epub 2007 Jul 9. Review.

PMID:
17618313
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

State of the art in African trypanosome drug discovery.

Jacobs RT, Nare B, Phillips MA.

Curr Top Med Chem. 2011;11(10):1255-74. Review.

PMID:
21401507
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Control and surveillance of human African trypanosomiasis.

World Health Organization.

World Health Organ Tech Rep Ser. 2013;(984):1-237.

PMID:
24552089
[PubMed - indexed for MEDLINE]
10.

Chemotherapy against human African trypanosomiasis: is there a road to success?

Burri C.

Parasitology. 2010 Dec;137(14):1987-94. doi: 10.1017/S0031182010001137. Epub 2010 Oct 20. Review.

PMID:
20961469
[PubMed - indexed for MEDLINE]
11.

Diamidines for human African trypanosomiasis.

Paine MF, Wang MZ, Generaux CN, Boykin DW, Wilson WD, De Koning HP, Olson CA, Pohlig G, Burri C, Brun R, Murilla GA, Thuita JK, Barrett MP, Tidwell RR.

Curr Opin Investig Drugs. 2010 Aug;11(8):876-83. Review.

PMID:
20721830
[PubMed - indexed for MEDLINE]
12.

Development of novel drugs for human African trypanosomiasis.

Brun R, Don R, Jacobs RT, Wang MZ, Barrett MP.

Future Microbiol. 2011 Jun;6(6):677-91. doi: 10.2217/fmb.11.44. Review.

PMID:
21707314
[PubMed - indexed for MEDLINE]
Free Article
13.

New drugs for the treatment of human African trypanosomiasis: research and development.

Keiser J, Stich A, Burri C.

Trends Parasitol. 2001 Jan;17(1):42-9.

PMID:
11137740
[PubMed - indexed for MEDLINE]
14.

Availability and affordability of treatment for Human African Trypanosomiasis.

Etchegorry MG, Helenport JP, Pecoul B, Jannin J, Legros D.

Trop Med Int Health. 2001 Nov;6(11):957-9.

PMID:
11703853
[PubMed - indexed for MEDLINE]
Free Article
15.

Eflornithine. A new drug in the treatment of sleeping sickness.

Van Bogaert I, Haemers A.

Pharm Weekbl Sci. 1989 Jun 23;11(3):69-75. Review.

PMID:
2505225
[PubMed - indexed for MEDLINE]
16.

Eflornithine for the treatment of human African trypanosomiasis.

Burri C, Brun R.

Parasitol Res. 2003 Jun;90 Supp 1:S49-52. Epub 2002 Dec 10. Review.

PMID:
12811548
[PubMed - indexed for MEDLINE]
17.

Hit-to-lead development of the chamigrane endoperoxide merulin A for the treatment of African sleeping sickness.

Navarro G, Chokpaiboon S, De Muylder G, Bray WM, Nisam SC, McKerrow JH, Pudhom K, Linington RG.

PLoS One. 2012;7(9):e46172. doi: 10.1371/journal.pone.0046172. Epub 2012 Sep 27.

PMID:
23029428
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Kinase scaffold repurposing for neglected disease drug discovery: discovery of an efficacious, lapatinib-derived lead compound for trypanosomiasis.

Patel G, Karver CE, Behera R, Guyett PJ, Sullenberger C, Edwards P, Roncal NE, Mensa-Wilmot K, Pollastri MP.

J Med Chem. 2013 May 23;56(10):3820-32. doi: 10.1021/jm400349k. Epub 2013 May 3.

PMID:
23597080
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

IMOL 881, a new trypanocidal compound.

Maes L, Songa EB, Hamers R.

Acta Trop. 1993 Sep;54(3-4):261-9.

PMID:
7902663
[PubMed - indexed for MEDLINE]
20.

Cross-resistance to nitro drugs and implications for treatment of human African trypanosomiasis.

Sokolova AY, Wyllie S, Patterson S, Oza SL, Read KD, Fairlamb AH.

Antimicrob Agents Chemother. 2010 Jul;54(7):2893-900. doi: 10.1128/AAC.00332-10. Epub 2010 May 3.

PMID:
20439607
[PubMed - indexed for MEDLINE]
Free PMC Article

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