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Items: 1 to 20 of 88


VprBP has intrinsic kinase activity targeting histone H2A and represses gene transcription.

Kim K, Kim JM, Kim JS, Choi J, Lee YS, Neamati N, Song JS, Heo K, An W.

Mol Cell. 2013 Nov 7;52(3):459-67. doi: 10.1016/j.molcel.2013.09.017. Epub 2013 Oct 17.


Vpr-binding protein antagonizes p53-mediated transcription via direct interaction with H3 tail.

Kim K, Heo K, Choi J, Jackson S, Kim H, Xiong Y, An W.

Mol Cell Biol. 2012 Feb;32(4):783-96. doi: 10.1128/MCB.06037-11. Epub 2011 Dec 19.


Autophagy negatively regulates cancer cell proliferation via selectively targeting VPRBP.

Wang BS, Liu YZ, Yang Y, Zhang Y, Hao JJ, Yang H, Wang XM, Zhang ZQ, Zhan QM, Wang MR.

Clin Sci (Lond). 2013 Feb;124(3):203-14. doi: 10.1042/CS20120270.


Human immunodeficiency virus type 1 Vpr-binding protein VprBP, a WD40 protein associated with the DDB1-CUL4 E3 ubiquitin ligase, is essential for DNA replication and embryonic development.

McCall CM, Miliani de Marval PL, Chastain PD 2nd, Jackson SC, He YJ, Kotake Y, Cook JG, Xiong Y.

Mol Cell Biol. 2008 Sep;28(18):5621-33. doi: 10.1128/MCB.00232-08. Epub 2008 Jul 7.


Weakly positioned nucleosomes enhance the transcriptional competency of chromatin.

Belch Y, Yang J, Liu Y, Malkaram SA, Liu R, Riethoven JJ, Ladunga I.

PLoS One. 2010 Sep 24;5(9):e12984. doi: 10.1371/journal.pone.0012984.


Formation of mobile chromatin-associated nuclear foci containing HIV-1 Vpr and VPRBP is critical for the induction of G2 cell cycle arrest.

Belzile JP, Abrahamyan LG, Gérard FC, Rougeau N, Cohen EA.

PLoS Pathog. 2010 Sep 2;6(9):e1001080. doi: 10.1371/journal.ppat.1001080.


The homeodomain transcription factor CDP/cut interacts with the cell cycle regulatory element of histone H4 genes packaged into nucleosomes.

Last TJ, van Wijnen AJ, de Ridder MC, Stein GS, Stein JL.

Mol Biol Rep. 1999 Aug;26(3):185-94.


Expression of P. falciparum var genes involves exchange of the histone variant H2A.Z at the promoter.

Petter M, Lee CC, Byrne TJ, Boysen KE, Volz J, Ralph SA, Cowman AF, Brown GV, Duffy MF.

PLoS Pathog. 2011 Feb;7(2):e1001292. doi: 10.1371/journal.ppat.1001292. Epub 2011 Feb 17.


Cell cycle-dependent changes in conformation and composition of nucleosomes containing human histone gene sequences.

Sterner R, Boffa LC, Chen TA, Allfrey VG.

Nucleic Acids Res. 1987 Jun 11;15(11):4375-91.


Phospho-H2A and cohesin specify distinct tension-regulated Sgo1 pools at kinetochores and inner centromeres.

Liu H, Jia L, Yu H.

Curr Biol. 2013 Oct 7;23(19):1927-33. doi: 10.1016/j.cub.2013.07.078. Epub 2013 Sep 19.


NuA4-dependent acetylation of nucleosomal histones H4 and H2A directly stimulates incorporation of H2A.Z by the SWR1 complex.

Altaf M, Auger A, Monnet-Saksouk J, Brodeur J, Piquet S, Cramet M, Bouchard N, Lacoste N, Utley RT, Gaudreau L, Côté J.

J Biol Chem. 2010 May 21;285(21):15966-77. doi: 10.1074/jbc.M110.117069. Epub 2010 Mar 23.


The chromatin remodeling protein, SRCAP, is critical for deposition of the histone variant H2A.Z at promoters.

Wong MM, Cox LK, Chrivia JC.

J Biol Chem. 2007 Sep 7;282(36):26132-9. Epub 2007 Jul 8.


Assembly and disassembly of nucleosome core particles containing histone variants by human nucleosome assembly protein I.

Okuwaki M, Kato K, Shimahara H, Tate S, Nagata K.

Mol Cell Biol. 2005 Dec;25(23):10639-51.


Splitting of H3-H4 tetramers at transcriptionally active genes undergoing dynamic histone exchange.

Katan-Khaykovich Y, Struhl K.

Proc Natl Acad Sci U S A. 2011 Jan 25;108(4):1296-301. doi: 10.1073/pnas.1018308108. Epub 2011 Jan 10.

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