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Items: 1 to 20 of 82

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Role of P450 1A1 and P450 1A2 in bioactivation versus detoxication of the renal carcinogen aristolochic acid I: studies in Cyp1a1-/-, Cyp1a2-/-, and Cyp1a1/1a2-/- mice.

Arlt VM, Levová K, Bárta F, Shi Z, Evans JD, Frei E, Schmeiser HH, Nebert DW, Phillips DH, Stiborová M.

Chem Res Toxicol. 2011 Oct 17;24(10):1710-9. doi: 10.1021/tx200259y. Epub 2011 Sep 29.

PMID:
21932800
4.

Cytochrome P450 enzyme levels in HepG2 cells and cryopreserved primary human hepatocytes and their induction in HepG2 cells.

Westerink WM, Schoonen WG.

Toxicol In Vitro. 2007 Dec;21(8):1581-91. Epub 2007 Jun 8.

PMID:
17637504
5.

Tobacco smoke-dependent changes in cytochrome P450 1A1, 1A2, and 2E1 protein expressions in fetuses, newborns, pregnant rats, and human placenta.

Czekaj P, Wiaderkiewicz A, Florek E, Wiaderkiewicz R.

Arch Toxicol. 2005 Jan;79(1):13-24. Epub 2004 Sep 23.

PMID:
15448981
6.

Inhibition of human cytochrome P450 enzymes by 1,2-dithiole-3-thione, oltipraz and its derivatives, and sulforaphane.

Langouët S, Furge LL, Kerriguy N, Nakamura K, Guillouzo A, Guengerich FP.

Chem Res Toxicol. 2000 Apr;13(4):245-52.

PMID:
10775323
7.

Salvianolic acid B modulates the expression of drug-metabolizing enzymes in HepG2 cells.

Wang QL, Wu Q, Tao YY, Liu CH, El-Nezami H.

Hepatobiliary Pancreat Dis Int. 2011 Oct;10(5):502-8.

9.

17 beta-estradiol hydroxylation catalyzed by human cytochrome P450 1A1: a comparison of the activities induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin in MCF-7 cells with those from heterologous expression of the cDNA.

Spink DC, Eugster HP, Lincoln DW 2nd, Schuetz JD, Schuetz EG, Johnson JA, Kaminsky LS, Gierthy JF.

Arch Biochem Biophys. 1992 Mar;293(2):342-8.

PMID:
1536570
10.

Dietary flavonoids: effects on xenobiotic and carcinogen metabolism.

Moon YJ, Wang X, Morris ME.

Toxicol In Vitro. 2006 Mar;20(2):187-210. Epub 2005 Nov 11. Review.

PMID:
16289744
12.

Contribution of human cytochrome p-450 isoforms to the metabolism of the simplest phenothiazine neuroleptic promazine.

Wójcikowski J, Pichard-Garcia L, Maurel P, Daniel WA.

Br J Pharmacol. 2003 Apr;138(8):1465-74.

13.

Resveratrol is a selective human cytochrome P450 1A1 inhibitor.

Chun YJ, Kim MY, Guengerich FP.

Biochem Biophys Res Commun. 1999 Aug 19;262(1):20-4.

PMID:
10448061
14.

Metabolism of 5-methylchrysene and 6-methylchrysene by human hepatic and pulmonary cytochrome P450 enzymes.

Koehl W, Amin S, Staretz ME, Ueng YF, Yamazaki H, Tateishi T, Guengerich FP, Hecht SS.

Cancer Res. 1996 Jan 15;56(2):316-24.

16.

Aryl acetylenes as mechanism-based inhibitors of cytochrome P450-dependent monooxygenase enzymes.

Foroozesh M, Primrose G, Guo Z, Bell LC, Alworth WL, Guengerich FP.

Chem Res Toxicol. 1997 Jan;10(1):91-102.

PMID:
9074808
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Cytochrome P450 (P450) isoenzyme specific dealkylation of alkoxyresorufins in rat brain microsomes.

Dhawan A, Parmar D, Dayal M, Seth PK.

Mol Cell Biochem. 1999 Oct;200(1-2):169-76.

PMID:
10569197
19.

Cytochrome P450 enzymes in drug metabolism: regulation of gene expression, enzyme activities, and impact of genetic variation.

Zanger UM, Schwab M.

Pharmacol Ther. 2013 Apr;138(1):103-41. doi: 10.1016/j.pharmthera.2012.12.007. Epub 2013 Jan 16. Review.

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