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Results: 1 to 20 of 114

1.

Stearoyl-CoA desaturase plays an important role in proliferation and chemoresistance in human hepatocellular carcinoma.

Bansal S, Berk M, Alkhouri N, Partrick DA, Fung JJ, Feldstein A.

J Surg Res. 2014 Jan;186(1):29-38. doi: 10.1016/j.jss.2013.07.001. Epub 2013 Jul 27.

PMID:
24135379
[PubMed - indexed for MEDLINE]
2.

Increased lipogenesis, induced by AKT-mTORC1-RPS6 signaling, promotes development of human hepatocellular carcinoma.

Calvisi DF, Wang C, Ho C, Ladu S, Lee SA, Mattu S, Destefanis G, Delogu S, Zimmermann A, Ericsson J, Brozzetti S, Staniscia T, Chen X, Dombrowski F, Evert M.

Gastroenterology. 2011 Mar;140(3):1071-83. doi: 10.1053/j.gastro.2010.12.006. Epub 2010 Dec 11.

PMID:
21147110
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Combined targeting of AKT and mTOR synergistically inhibits proliferation of hepatocellular carcinoma cells.

Grabinski N, Ewald F, Hofmann BT, Staufer K, Schumacher U, Nashan B, Jücker M.

Mol Cancer. 2012 Nov 20;11:85. doi: 10.1186/1476-4598-11-85.

PMID:
23167739
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Histone deacetylases activate hepatocyte growth factor signaling by repressing microRNA-449 in hepatocellular carcinoma cells.

Buurman R, Gürlevik E, Schäffer V, Eilers M, Sandbothe M, Kreipe H, Wilkens L, Schlegelberger B, Kühnel F, Skawran B.

Gastroenterology. 2012 Sep;143(3):811-20.e1-15. doi: 10.1053/j.gastro.2012.05.033. Epub 2012 May 26.

PMID:
22641068
[PubMed - indexed for MEDLINE]
5.

Over-expression of the mitogen-activated protein kinase (MAPK) kinase (MEK)-MAPK in hepatocellular carcinoma: its role in tumor progression and apoptosis.

Huynh H, Nguyen TT, Chow KH, Tan PH, Soo KC, Tran E.

BMC Gastroenterol. 2003 Aug 8;3:19.

PMID:
12906713
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Inhibition of MKK7-JNK by the TOR signaling pathway regulator-like protein contributes to resistance of HCC cells to TRAIL-induced apoptosis.

Song IS, Jun SY, Na HJ, Kim HT, Jung SY, Ha GH, Park YH, Long LZ, Yu DY, Kim JM, Kim JH, Ko JH, Kim CH, Kim NS.

Gastroenterology. 2012 Nov;143(5):1341-51. doi: 10.1053/j.gastro.2012.07.103. Epub 2012 Jul 27.

PMID:
22841785
[PubMed - indexed for MEDLINE]
7.

FGFR3 stimulates stearoyl CoA desaturase 1 activity to promote bladder tumor growth.

Du X, Wang QR, Chan E, Merchant M, Liu J, French D, Ashkenazi A, Qing J.

Cancer Res. 2012 Nov 15;72(22):5843-55. doi: 10.1158/0008-5472.CAN-12-1329. Epub 2012 Sep 26.

PMID:
23019225
[PubMed - indexed for MEDLINE]
Free Article
8.

HDGF-related protein-3 is required for anchorage-independent survival and chemoresistance in hepatocellular carcinomas.

Xiao Q, Qu K, Wang C, Kong Y, Liu C, Jiang D, Saiyin H, Jia F, Ni C, Chen T, Zhang Y, Zhang P, Qin W, Sun Q, Wang H, Yi Q, Liu J, Huang H, Yu L.

Gut. 2013 Mar;62(3):440-51. doi: 10.1136/gutjnl-2011-300781. Epub 2012 Apr 5.

PMID:
22490522
[PubMed - indexed for MEDLINE]
9.

Receptor for activated C kinase 1 promotes hepatocellular carcinoma growth by enhancing mitogen-activated protein kinase kinase 7 activity.

Guo Y, Wang W, Wang J, Feng J, Wang Q, Jin J, Lv M, Li X, Li Y, Ma Y, Shen B, Zhang J.

Hepatology. 2013 Jan;57(1):140-51. doi: 10.1002/hep.25978.

PMID:
22903704
[PubMed - indexed for MEDLINE]
10.

Arenobufagin, a natural bufadienolide from toad venom, induces apoptosis and autophagy in human hepatocellular carcinoma cells through inhibition of PI3K/Akt/mTOR pathway.

Zhang DM, Liu JS, Deng LJ, Chen MF, Yiu A, Cao HH, Tian HY, Fung KP, Kurihara H, Pan JX, Ye WC.

Carcinogenesis. 2013 Jun;34(6):1331-42. doi: 10.1093/carcin/bgt060. Epub 2013 Feb 7.

PMID:
23393227
[PubMed - indexed for MEDLINE]
Free Article
11.

Hepatoma cells from mice deficient in glycine N-methyltransferase have increased RAS signaling and activation of liver kinase B1.

Martínez-López N, García-Rodríguez JL, Varela-Rey M, Gutiérrez V, Fernández-Ramos D, Beraza N, Aransay AM, Schlangen K, Lozano JJ, Aspichueta P, Luka Z, Wagner C, Evert M, Calvisi DF, Lu SC, Mato JM, Martínez-Chantar ML.

Gastroenterology. 2012 Sep;143(3):787-98.e1-13. doi: 10.1053/j.gastro.2012.05.050. Epub 2012 Jun 8.

PMID:
22687285
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

MECP2 promotes cell proliferation by activating ERK1/2 and inhibiting p38 activity in human hepatocellular carcinoma HEPG2 cells.

Zhao LY, Zhang J, Guo B, Yang J, Han J, Zhao XG, Wang XF, Liu LY, Li ZF, Song TS, Huang C.

Cell Mol Biol (Noisy-le-grand). 2013 Nov 3;Suppl 59:OL1876-81.

PMID:
24199952
[PubMed - indexed for MEDLINE]
13.

P21-activated kinase 5 plays essential roles in the proliferation and tumorigenicity of human hepatocellular carcinoma.

Fang ZP, Jiang BG, Gu XF, Zhao B, Ge RL, Zhang FB.

Acta Pharmacol Sin. 2014 Jan;35(1):82-8. doi: 10.1038/aps.2013.31. Epub 2013 May 20.

PMID:
23685956
[PubMed - indexed for MEDLINE]
14.

JNK1, JNK2, and JNK3 are involved in P-glycoprotein-mediated multidrug resistance of hepatocellular carcinoma cells.

Yan F, Wang XM, Liu ZC, Pan C, Yuan SB, Ma QM.

Hepatobiliary Pancreat Dis Int. 2010 Jun;9(3):287-95.

PMID:
20525557
[PubMed - indexed for MEDLINE]
Free Article
15.

c-Jun NH2-terminal kinase pathway is involved in constitutive matrix metalloproteinase-1 expression in a hepatocellular carcinoma-derived cell line.

Sugioka Y, Watanabe T, Inagaki Y, Kushida M, Niioka M, Endo H, Higashiyama R, Okazaki I.

Int J Cancer. 2004 May 10;109(6):867-74.

PMID:
15027120
[PubMed - indexed for MEDLINE]
16.

Possible role of visfatin in hepatoma progression and the effects of branched-chain amino acids on visfatin-induced proliferation in human hepatoma cells.

Ninomiya S, Shimizu M, Imai K, Takai K, Shiraki M, Hara T, Tsurumi H, Ishizaki S, Moriwaki H.

Cancer Prev Res (Phila). 2011 Dec;4(12):2092-100. doi: 10.1158/1940-6207.CAPR-11-0340. Epub 2011 Sep 27.

PMID:
21952585
[PubMed - indexed for MEDLINE]
17.

FBI-1 promotes cell proliferation and enhances resistance to chemotherapy of hepatocellular carcinoma in vitro and in vivo.

Fang F, Yang L, Tao Y, Qin W.

Cancer. 2012 Jan 1;118(1):134-46. doi: 10.1002/cncr.26251. Epub 2011 Jun 28.

PMID:
21713761
[PubMed - indexed for MEDLINE]
Free Article
18.

Arsenic trioxide-induced growth arrest of human hepatocellular carcinoma cells involving FOXO3a expression and localization.

Fei M, Lu M, Wang Y, Zhao Y, He S, Gao S, Ke Q, Liu Y, Li P, Cui X, Shen A, Cheng C.

Med Oncol. 2009;26(2):178-85. doi: 10.1007/s12032-008-9105-8. Epub 2008 Oct 21.

PMID:
18937079
[PubMed - indexed for MEDLINE]
19.

Cyclooxygenase-2 promotes hepatocellular carcinoma cell growth through Akt activation: evidence for Akt inhibition in celecoxib-induced apoptosis.

Leng J, Han C, Demetris AJ, Michalopoulos GK, Wu T.

Hepatology. 2003 Sep;38(3):756-68.

PMID:
12939602
[PubMed - indexed for MEDLINE]
20.

Bid sensitizes apoptosis induced by chemotherapeutic drugs in hepatocellular carcinoma.

Miao J, Chen GG, Chun SY, Chak EC, Lai PB.

Int J Oncol. 2004 Sep;25(3):651-9.

PMID:
15289866
[PubMed - indexed for MEDLINE]

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