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Items: 1 to 20 of 101

1.

Structure and stability insights into tumour suppressor p53 evolutionary related proteins.

Pagano B, Jama A, Martinez P, Akanho E, Bui TT, Drake AF, Fraternali F, Nikolova PV.

PLoS One. 2013 Oct 4;8(10):e76014. doi: 10.1371/journal.pone.0076014. eCollection 2013.

2.

The p73 DNA binding domain displays enhanced stability relative to its homologue, the tumor suppressor p53, and exhibits cooperative DNA binding.

Patel S, Bui TT, Drake AF, Fraternali F, Nikolova PV.

Biochemistry. 2008 Mar 11;47(10):3235-44. doi: 10.1021/bi7023207. Epub 2008 Feb 9. Erratum in: Biochemistry. 2008 May 20;47(20):5679-80.

PMID:
18260640
3.

Tracing the protectors path from the germ line to the genome.

Coutandin D, Ou HD, Löhr F, Dötsch V.

Proc Natl Acad Sci U S A. 2010 Aug 31;107(35):15318-25. doi: 10.1073/pnas.1001069107. Epub 2010 Aug 9.

4.

Structural evolution of p53, p63, and p73: implication for heterotetramer formation.

Joerger AC, Rajagopalan S, Natan E, Veprintsev DB, Robinson CV, Fersht AR.

Proc Natl Acad Sci U S A. 2009 Oct 20;106(42):17705-10. doi: 10.1073/pnas.0905867106. Epub 2009 Oct 7.

5.

Structural evolution of C-terminal domains in the p53 family.

Ou HD, Löhr F, Vogel V, Mäntele W, Dötsch V.

EMBO J. 2007 Jul 25;26(14):3463-73. Epub 2007 Jun 21.

6.

Early diversification and complex evolutionary history of the p53 tumor suppressor gene family.

Nedelcu AM, Tan C.

Dev Genes Evol. 2007 Dec;217(11-12):801-6. Epub 2007 Oct 9.

PMID:
17924139
7.

Stability of the core domain of p53: insights from computer simulations.

Madhumalar A, Smith DJ, Verma C.

BMC Bioinformatics. 2008;9 Suppl 1:S17. doi: 10.1186/1471-2105-9-S1-S17.

8.

Structural basis for ASPP2 recognition by the tumor suppressor p73.

Canning P, von Delft F, Bullock AN.

J Mol Biol. 2012 Nov 2;423(4):515-27. doi: 10.1016/j.jmb.2012.08.005. Epub 2012 Aug 20.

9.

Structural basis for gene activation by p53 family members.

Scoumanne A, Harms KL, Chen X.

Cancer Biol Ther. 2005 Nov;4(11):1178-85. Epub 2005 Nov 18. Review.

PMID:
16294021
10.

Differences in the transactivation domains of p53 family members: a computational study.

Mavinahalli JN, Madhumalar A, Beuerman RW, Lane DP, Verma C.

BMC Genomics. 2010 Feb 10;11 Suppl 1:S5. doi: 10.1186/1471-2164-11-S1-S5.

11.

Tracing the evolution of the p53 tetramerization domain.

Joerger AC, Wilcken R, Andreeva A.

Structure. 2014 Sep 2;22(9):1301-10. doi: 10.1016/j.str.2014.07.010.

12.

C-terminal diversity within the p53 family accounts for differences in DNA binding and transcriptional activity.

Sauer M, Bretz AC, Beinoraviciute-Kellner R, Beitzinger M, Burek C, Rosenwald A, Harms GS, Stiewe T.

Nucleic Acids Res. 2008 Apr;36(6):1900-12. doi: 10.1093/nar/gkn044. Epub 2008 Feb 11.

13.

p73 and p63: why do we still need them?

Blandino G, Dobbelstein M.

Cell Cycle. 2004 Jul;3(7):886-94. Epub 2004 Jul 2. Review.

PMID:
15254416
14.

Adaptive evolution of p53 thermodynamic stability.

Khoo KH, Andreeva A, Fersht AR.

J Mol Biol. 2009 Oct 16;393(1):161-75. doi: 10.1016/j.jmb.2009.08.013. Epub 2009 Aug 13.

PMID:
19683006
15.

The C terminus of p53 family proteins is a cell fate determinant.

Harms KL, Chen X.

Mol Cell Biol. 2005 Mar;25(5):2014-30.

16.

High thermostability and lack of cooperative DNA binding distinguish the p63 core domain from the homologous tumor suppressor p53.

Klein C, Georges G, Künkele KP, Huber R, Engh RA, Hansen S.

J Biol Chem. 2001 Oct 5;276(40):37390-401. Epub 2001 Jul 26.

17.

Identification of DeltaN isoform and polyadenylation site choice variants in molluscan p63/p73-like homologues.

Muttray AF, Cox RL, Reinisch CL, Baldwin SA.

Mar Biotechnol (NY). 2007 Mar-Apr;9(2):217-30. Epub 2007 Jan 22.

PMID:
17242983
18.

Dimerization of the core domain of the p53 family: a computational study.

Madhumalar A, Jun LH, Lane DP, Verma CS.

Cell Cycle. 2009 Jan 1;8(1):137-48.

PMID:
19106606
19.

Molecular basis of S100 proteins interacting with the p53 homologs p63 and p73.

van Dieck J, Brandt T, Teufel DP, Veprintsev DB, Joerger AC, Fersht AR.

Oncogene. 2010 Apr 8;29(14):2024-35. doi: 10.1038/onc.2009.490. Epub 2010 Feb 8.

PMID:
20140014
20.

Structure and function in the p53 family.

Arrowsmith CH.

Cell Death Differ. 1999 Dec;6(12):1169-73. Review.

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