Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 103

1.

Directed evolution of an angiopoietin-2 ligand trap by somatic hypermutation and cell surface display.

Brindle NP, Sale JE, Arakawa H, Buerstedde JM, Nuamchit T, Sharma S, Steele KH.

J Biol Chem. 2013 Nov 15;288(46):33205-12. doi: 10.1074/jbc.M113.510578. Epub 2013 Oct 8.

PMID:
24106271
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Effects of angiopoietins-1 and -2 on the receptor tyrosine kinase Tie2 are differentially regulated at the endothelial cell surface.

Hansen TM, Singh H, Tahir TA, Brindle NP.

Cell Signal. 2010 Mar;22(3):527-32. doi: 10.1016/j.cellsig.2009.11.007. Epub .

PMID:
19922791
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

A designed angiopoietin-2 variant, pentameric COMP-Ang2, strongly activates Tie2 receptor and stimulates angiogenesis.

Kim HZ, Jung K, Kim HM, Cheng Y, Koh GY.

Biochim Biophys Acta. 2009 May;1793(5):772-80. doi: 10.1016/j.bbamcr.2009.01.018. Epub 2009 Feb 10.

PMID:
19339208
[PubMed - indexed for MEDLINE]
Free Article
4.

Angiopoietin-1, 2 and Tie2 expressions in endometrial adenocarcinoma--the Ang2 dominant balance up-regulates tumor angiogenesis in the presence of VEGF.

Saito M, Watanabe J, Fujisawa T, Kamata Y, Nishimura Y, Arai T, Miyamoto T, Obokata A, Kuramoto H.

Eur J Gynaecol Oncol. 2006;27(2):129-34.

PMID:
16620053
[PubMed - indexed for MEDLINE]
5.

Oligomerization and multimerization are critical for angiopoietin-1 to bind and phosphorylate Tie2.

Kim KT, Choi HH, Steinmetz MO, Maco B, Kammerer RA, Ahn SY, Kim HZ, Lee GM, Koh GY.

J Biol Chem. 2005 May 20;280(20):20126-31. Epub 2005 Mar 15.

PMID:
15769741
[PubMed - indexed for MEDLINE]
Free Article
6.

Biological action of angiopoietin-2 in a fibrin matrix model of angiogenesis is associated with activation of Tie2.

Teichert-Kuliszewska K, Maisonpierre PC, Jones N, Campbell AI, Master Z, Bendeck MP, Alitalo K, Dumont DJ, Yancopoulos GD, Stewart DJ.

Cardiovasc Res. 2001 Feb 16;49(3):659-70.

PMID:
11166279
[PubMed - indexed for MEDLINE]
Free Article
7.

Expression of angiopoietin-1, angiopoietin-2, and Tie2 genes in normal ovary with corpus luteum and in ovarian cancer.

Hata K, Udagawa J, Fujiwaki R, Nakayama K, Otani H, Miyazaki K.

Oncology. 2002;62(4):340-8.

PMID:
12138242
[PubMed - indexed for MEDLINE]
8.

Expressions of Angiopoietin-1, Angiopoietin-2, and Tie2 and their roles in rat renal allografts with chronic allograft nephropathy.

Ma X, Lu YP, Yang L, Song J, Luo GH, Shi YJ, Li YP.

Transplant Proc. 2008 Oct;40(8):2795-9. doi: 10.1016/j.transproceed.2008.07.121.

PMID:
18929864
[PubMed - indexed for MEDLINE]
9.

Structural basis for angiopoietin-1-mediated signaling initiation.

Yu X, Seegar TC, Dalton AC, Tzvetkova-Robev D, Goldgur Y, Rajashankar KR, Nikolov DB, Barton WA.

Proc Natl Acad Sci U S A. 2013 Apr 30;110(18):7205-10. doi: 10.1073/pnas.1216890110. Epub 2013 Apr 16.

PMID:
23592718
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Angiopoietin-2 functions as a Tie2 agonist in tumor models, where it limits the effects of VEGF inhibition.

Daly C, Eichten A, Castanaro C, Pasnikowski E, Adler A, Lalani AS, Papadopoulos N, Kyle AH, Minchinton AI, Yancopoulos GD, Thurston G.

Cancer Res. 2013 Jan 1;73(1):108-18. doi: 10.1158/0008-5472.CAN-12-2064. Epub 2012 Nov 13.

PMID:
23149917
[PubMed - indexed for MEDLINE]
Free Article
11.

Tie2 receptor ligands, angiopoietin-1 and angiopoietin-2, modulate VEGF-induced postnatal neovascularization.

Asahara T, Chen D, Takahashi T, Fujikawa K, Kearney M, Magner M, Yancopoulos GD, Isner JM.

Circ Res. 1998 Aug 10;83(3):233-40.

PMID:
9710115
[PubMed - indexed for MEDLINE]
Free Article
12.

Expression and function of Angiopoietins and their tie receptors in human basophils and mast cells.

Prevete N, Staiano RI, Granata F, Detoraki A, Necchi V, Ricci V, Triggiani M, De Paulis A, Marone G, Genovese A.

J Biol Regul Homeost Agents. 2013 Jul-Sep;27(3):827-39.

PMID:
24152847
[PubMed - indexed for MEDLINE]
13.

Angiotensin AT(1) and AT(2) receptors differentially regulate angiopoietin-2 and vascular endothelial growth factor expression and angiogenesis by modulating heparin binding-epidermal growth factor (EGF)-mediated EGF receptor transactivation.

Fujiyama S, Matsubara H, Nozawa Y, Maruyama K, Mori Y, Tsutsumi Y, Masaki H, Uchiyama Y, Koyama Y, Nose A, Iba O, Tateishi E, Ogata N, Jyo N, Higashiyama S, Iwasaka T.

Circ Res. 2001 Jan 19;88(1):22-9. Retraction in: Circ Res. 2013 Jun 7;112(12):e180.

PMID:
11139469
[PubMed - indexed for MEDLINE]
Free Article
14.

Rapamycin and cyclosporine have different effects on expression of Ang-1 and Ang-2 and Tie2 in rat renal allograft with chronic allograft nephropathy.

Ma X, Lu YP, Yang L, Song J, Luo GH, Shi YJ, Li YP.

Transplant Proc. 2008 Oct;40(8):2804-7. doi: 10.1016/j.transproceed.2008.08.047.

PMID:
18929866
[PubMed - indexed for MEDLINE]
15.

Tie1 regulates the Tie2 agonistic role of angiopoietin-2 in human lymphatic endothelial cells.

Song SH, Kim KL, Lee KA, Suh W.

Biochem Biophys Res Commun. 2012 Mar 9;419(2):281-6. doi: 10.1016/j.bbrc.2012.02.009. Epub 2012 Feb 10.

PMID:
22342979
[PubMed - indexed for MEDLINE]
16.

Enhanced expression of angiopoietin-2 and the Tie2 receptor but not angiopoietin-1 or the Tie1 receptor in a rat model of myocardial infarction.

Shyu KG, Liang YJ, Chang H, Wang BW, Leu JG, Kuan P.

J Biomed Sci. 2004 Mar-Apr;11(2):163-71.

PMID:
14966366
[PubMed - indexed for MEDLINE]
17.

Contrasting actions of selective inhibitors of angiopoietin-1 and angiopoietin-2 on the normalization of tumor blood vessels.

Falcón BL, Hashizume H, Koumoutsakos P, Chou J, Bready JV, Coxon A, Oliner JD, McDonald DM.

Am J Pathol. 2009 Nov;175(5):2159-70. doi: 10.2353/ajpath.2009.090391. Epub 2009 Oct 8.

PMID:
19815705
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Ligand oligomerization state controls Tie2 receptor trafficking and angiopoietin-2-specific responses.

Pietilä R, Nätynki M, Tammela T, Kangas J, Pulkki KH, Limaye N, Vikkula M, Koh GY, Saharinen P, Alitalo K, Eklund L.

J Cell Sci. 2012 May 1;125(Pt 9):2212-23. doi: 10.1242/jcs.098020. Epub 2012 Feb 22.

PMID:
22357955
[PubMed - indexed for MEDLINE]
Free Article
19.

Autocrine/paracrine role of the angiopoietin-1 and -2/Tie2 system in cell proliferation and chemotaxis of cultured fibroblastic synoviocytes in rheumatoid arthritis.

Takahara K, Iioka T, Furukawa K, Uchida T, Nakashima M, Tsukazaki T, Shindo H.

Hum Pathol. 2004 Feb;35(2):150-8.

PMID:
14991531
[PubMed - indexed for MEDLINE]
20.

Angiopoietin 2 is a partial agonist/antagonist of Tie2 signaling in the endothelium.

Yuan HT, Khankin EV, Karumanchi SA, Parikh SM.

Mol Cell Biol. 2009 Apr;29(8):2011-22. doi: 10.1128/MCB.01472-08. Epub 2009 Feb 17. Erratum in: Mol Cell Biol. 2009 Jun;29(12):3451.

PMID:
19223473
[PubMed - indexed for MEDLINE]
Free PMC Article

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk