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Items: 1 to 20 of 88

1.

Female neuregulin 1 heterozygous mice require repeated exposure to Δ⁹-tetrahydrocannabinol to alter sensorimotor gating function.

Spencer JR, Chohan TW, Karl T, Arnold JC.

Pharmacopsychiatry. 2013 Nov;46(7):286-91. doi: 10.1055/s-0033-1355390. Epub 2013 Oct 8.

PMID:
24105081
2.

Heterozygous neuregulin 1 mice are more sensitive to the behavioural effects of Delta9-tetrahydrocannabinol.

Boucher AA, Arnold JC, Duffy L, Schofield PR, Micheau J, Karl T.

Psychopharmacology (Berl). 2007 Jun;192(3):325-36. Epub 2007 Feb 28.

PMID:
17333138
3.

A follow-up study: acute behavioural effects of Delta(9)-THC in female heterozygous neuregulin 1 transmembrane domain mutant mice.

Long LE, Chesworth R, Arnold JC, Karl T.

Psychopharmacology (Berl). 2010 Aug;211(3):277-89. doi: 10.1007/s00213-010-1896-6. Epub 2010 Jun 23.

PMID:
20571781
4.

Adolescent neuregulin 1 heterozygous mice display enhanced behavioural sensitivity to methamphetamine.

Spencer JR, Darbyshire KM, Boucher AA, Arnold JC.

Prog Neuropsychopharmacol Biol Psychiatry. 2012 Dec 3;39(2):376-81. doi: 10.1016/j.pnpbp.2012.07.014. Epub 2012 Jul 29.

PMID:
22850204
5.

The schizophrenia susceptibility gene neuregulin 1 modulates tolerance to the effects of cannabinoids.

Boucher AA, Hunt GE, Micheau J, Huang X, McGregor IS, Karl T, Arnold JC.

Int J Neuropsychopharmacol. 2011 Jun;14(5):631-43. doi: 10.1017/S146114571000091X. Epub 2010 Aug 12.

PMID:
20701826
6.

Transmembrane domain Nrg1 mutant mice show altered susceptibility to the neurobehavioural actions of repeated THC exposure in adolescence.

Long LE, Chesworth R, Huang XF, McGregor IS, Arnold JC, Karl T.

Int J Neuropsychopharmacol. 2013 Feb;16(1):163-75. doi: 10.1017/S1461145711001854. Epub 2012 Jan 9.

PMID:
22226049
7.

Distinct neurobehavioural effects of cannabidiol in transmembrane domain neuregulin 1 mutant mice.

Long LE, Chesworth R, Huang XF, Wong A, Spiro A, McGregor IS, Arnold JC, Karl T.

PLoS One. 2012;7(4):e34129. doi: 10.1371/journal.pone.0034129. Epub 2012 Apr 3.

8.

Heterozygous neuregulin 1 mice display greater baseline and Delta(9)-tetrahydrocannabinol-induced c-Fos expression.

Boucher AA, Hunt GE, Karl T, Micheau J, McGregor IS, Arnold JC.

Neuroscience. 2007 Nov 23;149(4):861-70. Epub 2007 Aug 28.

PMID:
17905522
9.

Partial genetic deletion of neuregulin 1 modulates the effects of stress on sensorimotor gating, dendritic morphology, and HPA axis activity in adolescent mice.

Chohan TW, Boucher AA, Spencer JR, Kassem MS, Hamdi AA, Karl T, Fok SY, Bennett MR, Arnold JC.

Schizophr Bull. 2014 Nov;40(6):1272-84. doi: 10.1093/schbul/sbt193. Epub 2014 Jan 17.

10.

Do transmembrane domain neuregulin 1 mutant mice exhibit a reliable sensorimotor gating deficit?

Karl T, Burne TH, Van den Buuse M, Chesworth R.

Behav Brain Res. 2011 Oct 1;223(2):336-41. doi: 10.1016/j.bbr.2011.04.051. Epub 2011 May 13.

PMID:
21605597
11.

Novel molecular changes induced by Nrg1 hypomorphism and Nrg1-cannabinoid interaction in adolescence: a hippocampal proteomic study in mice.

Spencer JR, Darbyshire KM, Boucher AA, Kashem MA, Long LE, McGregor IS, Karl T, Arnold JC.

Front Cell Neurosci. 2013 Feb 26;7:15. doi: 10.3389/fncel.2013.00015. eCollection 2013.

12.

Disruption to social dyadic interactions but not emotional/anxiety-related behaviour in mice with heterozygous 'knockout' of the schizophrenia risk gene neuregulin-1.

O'Tuathaigh CM, O'Connor AM, O'Sullivan GJ, Lai D, Harvey R, Croke DT, Waddington JL.

Prog Neuropsychopharmacol Biol Psychiatry. 2008 Feb 15;32(2):462-6. Epub 2007 Sep 29.

PMID:
17980471
13.

Altered motor activity, exploration and anxiety in heterozygous neuregulin 1 mutant mice: implications for understanding schizophrenia.

Karl T, Duffy L, Scimone A, Harvey RP, Schofield PR.

Genes Brain Behav. 2007 Oct;6(7):677-87. Epub 2007 Feb 13.

14.

Neuregulin 1 expression and electrophysiological abnormalities in the Neuregulin 1 transmembrane domain heterozygous mutant mouse.

Long LE, Anderson P, Frank E, Shaw A, Liu S, Huang XF, Pinault D, Karl T, O'Brien TJ, Shannon Weickert C, Jones NC.

PLoS One. 2015 May 19;10(5):e0124114. doi: 10.1371/journal.pone.0124114. eCollection 2015.

15.

Fronto-temporal-mesolimbic gene expression and heritable differences in amphetamine-disrupted sensorimotor gating in rats.

Swerdlow NR, Shilling PD, Breier M, Trim RS, Light GA, Marie RS.

Psychopharmacology (Berl). 2012 Dec;224(3):349-62. doi: 10.1007/s00213-012-2758-1. Epub 2012 Jun 15.

PMID:
22700037
16.

Acute administration of Δ⁹ tetrahydrocannabinol does not prevent enhancement of sensory gating by clozapine in DBA/2 mice.

Smucny J, Stevens KE, Tregellas JR.

Pharmacol Biochem Behav. 2014 Mar;118:22-9. doi: 10.1016/j.pbb.2014.01.001. Epub 2014 Jan 10.

17.

Developmentally vitamin D-deficient rats show enhanced prepulse inhibition after acute Δ9-tetrahydrocannabinol.

Burne TH, Alexander S, Turner KM, Eyles DW, McGrath JJ.

Behav Pharmacol. 2014 Jun;25(3):236-44. doi: 10.1097/FBP.0000000000000041.

PMID:
24776491
18.

The influence of schizophrenia-related neuregulin-1 polymorphisms on sensorimotor gating in healthy males.

Roussos P, Giakoumaki SG, Adamaki E, Bitsios P.

Biol Psychiatry. 2011 Mar 1;69(5):479-86. doi: 10.1016/j.biopsych.2010.09.009. Epub 2010 Oct 30.

PMID:
21035784
19.

Type III neuregulin-1 is required for normal sensorimotor gating, memory-related behaviors, and corticostriatal circuit components.

Chen YJ, Johnson MA, Lieberman MD, Goodchild RE, Schobel S, Lewandowski N, Rosoklija G, Liu RC, Gingrich JA, Small S, Moore H, Dwork AJ, Talmage DA, Role LW.

J Neurosci. 2008 Jul 2;28(27):6872-83. doi: 10.1523/JNEUROSCI.1815-08.2008.

20.

Pharmacological effects of acute and repeated administration of Delta(9)-tetrahydrocannabinol in adolescent and adult rats.

Wiley JL, O'connell MM, Tokarz ME, Wright MJ Jr.

J Pharmacol Exp Ther. 2007 Mar;320(3):1097-105. Epub 2006 Dec 15.

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