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Results: 1 to 20 of 118

1.

Serum deprivation inhibits the transcriptional co-activator YAP and cell growth via phosphorylation of the 130-kDa isoform of Angiomotin by the LATS1/2 protein kinases.

Adler JJ, Johnson DE, Heller BL, Bringman LR, Ranahan WP, Conwell MD, Sun Y, Hudmon A, Wells CD.

Proc Natl Acad Sci U S A. 2013 Oct 22;110(43):17368-73. doi: 10.1073/pnas.1308236110. Epub 2013 Oct 7.

PMID:
24101513
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Amot130 adapts atrophin-1 interacting protein 4 to inhibit yes-associated protein signaling and cell growth.

Adler JJ, Heller BL, Bringman LR, Ranahan WP, Cocklin RR, Goebl MG, Oh M, Lim HS, Ingham RJ, Wells CD.

J Biol Chem. 2013 May 24;288(21):15181-93. doi: 10.1074/jbc.M112.446534. Epub 2013 Apr 5.

PMID:
23564455
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Actin-binding and cell proliferation activities of angiomotin family members are regulated by Hippo pathway-mediated phosphorylation.

Chan SW, Lim CJ, Guo F, Tan I, Leung T, Hong W.

J Biol Chem. 2013 Dec 27;288(52):37296-307. doi: 10.1074/jbc.M113.527598. Epub 2013 Nov 13.

PMID:
24225952
[PubMed - indexed for MEDLINE]
4.

Tumor suppressor LATS1 is a negative regulator of oncogene YAP.

Hao Y, Chun A, Cheung K, Rashidi B, Yang X.

J Biol Chem. 2008 Feb 29;283(9):5496-509. Epub 2007 Dec 24.

PMID:
18158288
[PubMed - indexed for MEDLINE]
Free Article
5.

Phosphorylation of angiomotin by Lats1/2 kinases inhibits F-actin binding, cell migration, and angiogenesis.

Dai X, She P, Chi F, Feng Y, Liu H, Jin D, Zhao Y, Guo X, Jiang D, Guan KL, Zhong TP, Zhao B.

J Biol Chem. 2013 Nov 22;288(47):34041-51. doi: 10.1074/jbc.M113.518019. Epub 2013 Oct 8.

PMID:
24106267
[PubMed - indexed for MEDLINE]
6.

Angiomotin family proteins are novel activators of the LATS2 kinase tumor suppressor.

Paramasivam M, Sarkeshik A, Yates JR 3rd, Fernandes MJ, McCollum D.

Mol Biol Cell. 2011 Oct;22(19):3725-33. doi: 10.1091/mbc.E11-04-0300. Epub 2011 Aug 10.

PMID:
21832154
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Heat shock protein 90 inhibition depletes LATS1 and LATS2, two regulators of the mammalian hippo tumor suppressor pathway.

Huntoon CJ, Nye MD, Geng L, Peterson KL, Flatten KS, Haluska P, Kaufmann SH, Karnitz LM.

Cancer Res. 2010 Nov 1;70(21):8642-50. doi: 10.1158/0008-5472.CAN-10-1345. Epub 2010 Sep 14.

PMID:
20841485
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

The p130 isoform of angiomotin is required for Yap-mediated hepatic epithelial cell proliferation and tumorigenesis.

Yi C, Shen Z, Stemmer-Rachamimov A, Dawany N, Troutman S, Showe LC, Liu Q, Shimono A, Sudol M, Holmgren L, Stanger BZ, Kissil JL.

Sci Signal. 2013 Sep 3;6(291):ra77. doi: 10.1126/scisignal.2004060.

PMID:
24003254
[PubMed - indexed for MEDLINE]
9.

KIBRA regulates Hippo signaling activity via interactions with large tumor suppressor kinases.

Xiao L, Chen Y, Ji M, Dong J.

J Biol Chem. 2011 Mar 11;286(10):7788-96. doi: 10.1074/jbc.M110.173468. Epub 2011 Jan 13.

PMID:
21233212
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP).

Zhao B, Li L, Tumaneng K, Wang CY, Guan KL.

Genes Dev. 2010 Jan 1;24(1):72-85. doi: 10.1101/gad.1843810.

PMID:
20048001
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Arsenic-induced cutaneous hyperplastic lesions are associated with the dysregulation of Yap, a Hippo signaling-related protein.

Li C, Srivastava RK, Elmets CA, Afaq F, Athar M.

Biochem Biophys Res Commun. 2013 Sep 6;438(4):607-12. doi: 10.1016/j.bbrc.2013.08.008. Epub 2013 Aug 11.

PMID:
23942117
[PubMed - indexed for MEDLINE]
12.

Itch E3 ubiquitin ligase regulates large tumor suppressor 1 stability [corrected].

Ho KC, Zhou Z, She YM, Chun A, Cyr TD, Yang X.

Proc Natl Acad Sci U S A. 2011 Mar 22;108(12):4870-5. doi: 10.1073/pnas.1101273108. Epub 2011 Mar 7. Erratum in: Proc Natl Acad Sci U S A.2011 May 3;108(18):8914.

PMID:
21383157
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Cytoplasmic ASPP1 inhibits apoptosis through the control of YAP.

Vigneron AM, Ludwig RL, Vousden KH.

Genes Dev. 2010 Nov 1;24(21):2430-9. doi: 10.1101/gad.1954310.

PMID:
21041411
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Mst2 and Lats kinases regulate apoptotic function of Yes kinase-associated protein (YAP).

Oka T, Mazack V, Sudol M.

J Biol Chem. 2008 Oct 10;283(41):27534-46. doi: 10.1074/jbc.M804380200. Epub 2008 Jul 17.

PMID:
18640976
[PubMed - indexed for MEDLINE]
Free Article
15.

The Hippo pathway member Nf2 is required for inner cell mass specification.

Cockburn K, Biechele S, Garner J, Rossant J.

Curr Biol. 2013 Jul 8;23(13):1195-201. doi: 10.1016/j.cub.2013.05.044. Epub 2013 Jun 20.

PMID:
23791728
[PubMed - indexed for MEDLINE]
16.

Effect of Mst1 overexpression on the growth of human hepatocellular carcinoma HepG2 cells and the sensitivity to cisplatin in vitro.

Xu C, Liu C, Huang W, Tu S, Wan F.

Acta Biochim Biophys Sin (Shanghai). 2013 Apr;45(4):268-79. doi: 10.1093/abbs/gmt006. Epub 2013 Feb 17. Erratum in: Acta Biochim Biophys Sin (Shanghai). 2013 Sep;45(9):801.

PMID:
23419720
[PubMed - indexed for MEDLINE]
17.

Regulation of Hippo pathway by mitogenic growth factors via phosphoinositide 3-kinase and phosphoinositide-dependent kinase-1.

Fan R, Kim NG, Gumbiner BM.

Proc Natl Acad Sci U S A. 2013 Feb 12;110(7):2569-74. doi: 10.1073/pnas.1216462110. Epub 2013 Jan 28.

PMID:
23359693
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Angiomotin'g YAP into the nucleus for cell proliferation and cancer development.

Hong W.

Sci Signal. 2013 Sep 3;6(291):pe27. doi: 10.1126/scisignal.2004573. Review.

PMID:
24003252
[PubMed - indexed for MEDLINE]
19.

LKB1 tumor suppressor regulates AMP kinase/mTOR-independent cell growth and proliferation via the phosphorylation of Yap.

Nguyen HB, Babcock JT, Wells CD, Quilliam LA.

Oncogene. 2013 Aug 29;32(35):4100-9. doi: 10.1038/onc.2012.431. Epub 2012 Oct 1.

PMID:
23027127
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Interplay of mevalonate and Hippo pathways regulates RHAMM transcription via YAP to modulate breast cancer cell motility.

Wang Z, Wu Y, Wang H, Zhang Y, Mei L, Fang X, Zhang X, Zhang F, Chen H, Liu Y, Jiang Y, Sun S, Zheng Y, Li N, Huang L.

Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):E89-98. doi: 10.1073/pnas.1319190110. Epub 2013 Dec 23.

PMID:
24367099
[PubMed - indexed for MEDLINE]
Free PMC Article

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