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Items: 1 to 20 of 86


Generation of prostate tumor-initiating cells is associated with elevation of reactive oxygen species and IL-6/STAT3 signaling.

Qu Y, Oyan AM, Liu R, Hua Y, Zhang J, Hovland R, Popa M, Liu X, Brokstad KA, Simon R, Molven A, Lin B, Zhang WD, McCormack E, Kalland KH, Ke XS.

Cancer Res. 2013 Dec 1;73(23):7090-100. doi: 10.1158/0008-5472.CAN-13-1560. Epub 2013 Oct 7.


Inhibition of STAT3 signaling targets both tumor-initiating and differentiated cell populations in prostate cancer.

Han Z, Wang X, Ma L, Chen L, Xiao M, Huang L, Cao Y, Bai J, Ma D, Zhou J, Hong Z.

Oncotarget. 2014 Sep 30;5(18):8416-28.


Characterization of sphere-propagating cells with stem-like properties from DU145 prostate cancer cells.

Rybak AP, He L, Kapoor A, Cutz JC, Tang D.

Biochim Biophys Acta. 2011 May;1813(5):683-94. doi: 10.1016/j.bbamcr.2011.01.018. Epub 2011 Jan 26.


Ursolic acid inhibits the growth of colon cancer-initiating cells by targeting STAT3.

Wang W, Zhao C, Jou D, Lü J, Zhang C, Lin L, Lin J.

Anticancer Res. 2013 Oct;33(10):4279-84.


Mesenchymal stem cells enhance lung cancer initiation through activation of IL-6/JAK2/STAT3 pathway.

Hsu HS, Lin JH, Hsu TW, Su K, Wang CW, Yang KY, Chiou SH, Hung SC.

Lung Cancer. 2012 Feb;75(2):167-77. doi: 10.1016/j.lungcan.2011.07.001. Epub 2011 Jul 28.


Penta-1,2,3,4,6-O-galloyl-beta-D-glucose induces p53 and inhibits STAT3 in prostate cancer cells in vitro and suppresses prostate xenograft tumor growth in vivo.

Hu H, Lee HJ, Jiang C, Zhang J, Wang L, Zhao Y, Xiang Q, Lee EO, Kim SH, Lü J.

Mol Cancer Ther. 2008 Sep;7(9):2681-91. doi: 10.1158/1535-7163.MCT-08-0456. Erratum in: Mol Cancer Ther. 2008 Nov;7(11):3654.


Interleukin-6 induces prostate cancer cell growth accompanied by activation of stat3 signaling pathway .

Lou W, Ni Z, Dyer K, Tweardy DJ, Gao AC.

Prostate. 2000 Feb 15;42(3):239-42.


IL-6 enriched lung cancer stem-like cell population by inhibition of cell cycle regulators via DNMT1 upregulation.

Liu CC, Lin JH, Hsu TW, Su K, Li AF, Hsu HS, Hung SC.

Int J Cancer. 2015 Feb 1;136(3):547-59. doi: 10.1002/ijc.29033. Epub 2014 Jun 27.


Ursolic acid inhibits multiple cell survival pathways leading to suppression of growth of prostate cancer xenograft in nude mice.

Shanmugam MK, Rajendran P, Li F, Nema T, Vali S, Abbasi T, Kapoor S, Sharma A, Kumar AP, Ho PC, Hui KM, Sethi G.

J Mol Med (Berl). 2011 Jul;89(7):713-27. doi: 10.1007/s00109-011-0746-2. Epub 2011 Apr 5.


STAT3 signaling is activated preferentially in tumor-initiating cells in claudin-low models of human breast cancer.

Wei W, Tweardy DJ, Zhang M, Zhang X, Landua J, Petrovic I, Bu W, Roarty K, Hilsenbeck SG, Rosen JM, Lewis MT.

Stem Cells. 2014 Oct;32(10):2571-82. doi: 10.1002/stem.1752.


Loss of androgen receptor expression promotes a stem-like cell phenotype in prostate cancer through STAT3 signaling.

Schroeder A, Herrmann A, Cherryholmes G, Kowolik C, Buettner R, Pal S, Yu H, Müller-Newen G, Jove R.

Cancer Res. 2014 Feb 15;74(4):1227-37. doi: 10.1158/0008-5472.CAN-13-0594. Epub 2013 Oct 31.


Sphere-forming cell subpopulations with cancer stem cell properties in human hepatoma cell lines.

Cao L, Zhou Y, Zhai B, Liao J, Xu W, Zhang R, Li J, Zhang Y, Chen L, Qian H, Wu M, Yin Z.

BMC Gastroenterol. 2011 Jun 14;11:71. doi: 10.1186/1471-230X-11-71.


Propagation of human prostate cancer stem-like cells occurs through EGFR-mediated ERK activation.

Rybak AP, Ingram AJ, Tang D.

PLoS One. 2013 Apr 19;8(4):e61716. doi: 10.1371/journal.pone.0061716. Print 2013.


Significance of IL-6 in the transition of hormone-resistant prostate cancer and the induction of myeloid-derived suppressor cells.

Wu CT, Hsieh CC, Lin CC, Chen WC, Hong JH, Chen MF.

J Mol Med (Berl). 2012 Nov;90(11):1343-55. doi: 10.1007/s00109-012-0916-x. Epub 2012 Jun 3. Erratum in: J Mol Med (Berl). 2013 May;91(5):649-50.


NADPH oxidase subunit p22(phox)-mediated reactive oxygen species contribute to angiogenesis and tumor growth through AKT and ERK1/2 signaling pathways in prostate cancer.

Li Q, Fu GB, Zheng JT, He J, Niu XB, Chen QD, Yin Y, Qian X, Xu Q, Wang M, Sun AF, Shu Y, Rui H, Liu LZ, Jiang BH.

Biochim Biophys Acta. 2013 Dec;1833(12):3375-85. doi: 10.1016/j.bbamcr.2013.09.018. Epub 2013 Oct 8.


Galiellalactone inhibits stem cell-like ALDH-positive prostate cancer cells.

Hellsten R, Johansson M, Dahlman A, Sterner O, Bjartell A.

PLoS One. 2011;6(7):e22118. doi: 10.1371/journal.pone.0022118. Epub 2011 Jul 11.


STAT3 activation by IL-6 from mesenchymal stem cells promotes the proliferation and metastasis of osteosarcoma.

Tu B, Du L, Fan QM, Tang Z, Tang TT.

Cancer Lett. 2012 Dec 1;325(1):80-8. doi: 10.1016/j.canlet.2012.06.006. Epub 2012 Jun 26.

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