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Results: 1 to 20 of 118

1.

The transcription factor HNF1α induces expression of angiotensin-converting enzyme 2 (ACE2) in pancreatic islets from evolutionarily conserved promoter motifs.

Pedersen KB, Chhabra KH, Nguyen VK, Xia H, Lazartigues E.

Biochim Biophys Acta. 2013 Nov;1829(11):1225-35. doi: 10.1016/j.bbagrm.2013.09.007. Epub 2013 Oct 5.

PMID:
24100303
[PubMed - indexed for MEDLINE]
2.

Identification of target genes of the transcription factor HNF1beta and HNF1alpha in a human embryonic kidney cell line.

Senkel S, Lucas B, Klein-Hitpass L, Ryffel GU.

Biochim Biophys Acta. 2005 Dec 20;1731(3):179-90. Epub 2005 Nov 2.

PMID:
16297991
[PubMed - indexed for MEDLINE]
Free Article
3.

Regulation of the expression of human organic anion transporter 3 by hepatocyte nuclear factor 1alpha/beta and DNA methylation.

Kikuchi R, Kusuhara H, Hattori N, Shiota K, Kim I, Gonzalez FJ, Sugiyama Y.

Mol Pharmacol. 2006 Sep;70(3):887-96. Epub 2006 Jun 22.

PMID:
16793932
[PubMed - indexed for MEDLINE]
Free Article
4.

Pancreatic angiotensin-converting enzyme 2 improves glycemia in angiotensin II-infused mice.

Chhabra KH, Xia H, Pedersen KB, Speth RC, Lazartigues E.

Am J Physiol Endocrinol Metab. 2013 Apr 15;304(8):E874-84. doi: 10.1152/ajpendo.00490.2012. Epub 2013 Mar 5.

PMID:
23462816
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Transcriptional regulation of human and mouse organic anion transporter 1 by hepatocyte nuclear factor 1 alpha/beta.

Saji T, Kikuchi R, Kusuhara H, Kim I, Gonzalez FJ, Sugiyama Y.

J Pharmacol Exp Ther. 2008 Feb;324(2):784-90. Epub 2007 Nov 20.

PMID:
18029548
[PubMed - indexed for MEDLINE]
Free Article
6.

Angiotensin I-converting enzyme type 2 (ACE2) gene therapy improves glycemic control in diabetic mice.

Bindom SM, Hans CP, Xia H, Boulares AH, Lazartigues E.

Diabetes. 2010 Oct;59(10):2540-8. doi: 10.2337/db09-0782. Epub 2010 Jul 26.

PMID:
20660625
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Hnf1alpha (MODY3) controls tissue-specific transcriptional programs and exerts opposed effects on cell growth in pancreatic islets and liver.

Servitja JM, Pignatelli M, Maestro MA, Cardalda C, Boj SF, Lozano J, Blanco E, Lafuente A, McCarthy MI, Sumoy L, Guigó R, Ferrer J.

Mol Cell Biol. 2009 Jun;29(11):2945-59. doi: 10.1128/MCB.01389-08. Epub 2009 Mar 16.

PMID:
19289501
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

A conditional model reveals that induction of hepatocyte nuclear factor-1alpha in Hnf1alpha-null mutant beta-cells can activate silenced genes postnatally, whereas overexpression is deleterious.

Luco RF, Maestro MA, del Pozo N, Philbrick WM, de la Ossa PP, Ferrer J.

Diabetes. 2006 Aug;55(8):2202-11.

PMID:
16873682
[PubMed - indexed for MEDLINE]
Free Article
9.

The mouse alpha-albumin (afamin) promoter is differentially regulated by hepatocyte nuclear factor 1α and hepatocyte nuclear factor 1β.

Liu H, Ren H, Spear BT.

DNA Cell Biol. 2011 Mar;30(3):137-47. doi: 10.1089/dna.2010.1097. Epub 2010 Oct 27.

PMID:
20979532
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Vitamin D-binding protein gene transcription is regulated by the relative abundance of hepatocyte nuclear factors 1alpha and 1beta.

Song YH, Ray K, Liebhaber SA, Cooke NE.

J Biol Chem. 1998 Oct 23;273(43):28408-18.

PMID:
9774468
[PubMed - indexed for MEDLINE]
Free Article
11.

Distinct regulation of hepatic nuclear factor 1alpha by NKX6.1 in pancreatic beta cells.

Donelan W, Koya V, Li SW, Yang LJ.

J Biol Chem. 2010 Apr 16;285(16):12181-9. doi: 10.1074/jbc.M109.064238. Epub 2010 Jan 27.

PMID:
20106981
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Selective deletion of the Hnf1beta (MODY5) gene in beta-cells leads to altered gene expression and defective insulin release.

Wang L, Coffinier C, Thomas MK, Gresh L, Eddu G, Manor T, Levitsky LL, Yaniv M, Rhoads DB.

Endocrinology. 2004 Aug;145(8):3941-9. Epub 2004 May 13.

PMID:
15142986
[PubMed - indexed for MEDLINE]
13.

Two distinct teleost hepatocyte nuclear factor 1 genes, hnf1alpha/tcf1 and hnf1beta/tcf2, abundantly expressed in liver, pancreas, gut and kidney of zebrafish.

Gong HY, Lin CJ, Chen MH, Hu MC, Lin GH, Zhou Y, Zon LI, Wu JL.

Gene. 2004 Aug 18;338(1):35-46.

PMID:
15302404
[PubMed - indexed for MEDLINE]
14.

A transcription factor regulatory circuit in differentiated pancreatic cells.

Boj SF, Parrizas M, Maestro MA, Ferrer J.

Proc Natl Acad Sci U S A. 2001 Dec 4;98(25):14481-6. Epub 2001 Nov 20.

PMID:
11717395
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Distinct roles of HNF1beta, HNF1alpha, and HNF4alpha in regulating pancreas development, beta-cell function and growth.

Maestro MA, Cardalda C, Boj SF, Luco RF, Servitja JM, Ferrer J.

Endocr Dev. 2007;12:33-45. Review.

PMID:
17923767
[PubMed - indexed for MEDLINE]
16.

Germline hepatocyte nuclear factor 1alpha and 1beta mutations in renal cell carcinomas.

Rebouissou S, Vasiliu V, Thomas C, Bellanné-Chantelot C, Bui H, Chrétien Y, Timsit J, Rosty C, Laurent-Puig P, Chauveau D, Zucman-Rossi J.

Hum Mol Genet. 2005 Mar 1;14(5):603-14. Epub 2005 Jan 13.

PMID:
15649945
[PubMed - indexed for MEDLINE]
Free Article
18.

Tissue-specific and glucose-responsive expression of the pancreatic derived factor (PANDER) promoter.

Burkhardt BR, Yang MC, Robert CE, Greene SR, McFadden KK, Yang J, Wu J, Gao Z, Wolf BA.

Biochim Biophys Acta. 2005 Sep 25;1730(3):215-25.

PMID:
16102856
[PubMed - indexed for MEDLINE]
Free Article
19.

Regulation of tissue-specific expression of the human and mouse urate transporter 1 gene by hepatocyte nuclear factor 1 alpha/beta and DNA methylation.

Kikuchi R, Kusuhara H, Hattori N, Kim I, Shiota K, Gonzalez FJ, Sugiyama Y.

Mol Pharmacol. 2007 Dec;72(6):1619-25. Epub 2007 Sep 13.

PMID:
17855651
[PubMed - indexed for MEDLINE]
Free Article
20.

Hnf1α (MODY3) regulates β-cell-enriched MafA transcription factor expression.

Hunter CS, Maestro MA, Raum JC, Guo M, Thompson FH 3rd, Ferrer J, Stein R.

Mol Endocrinol. 2011 Feb;25(2):339-47. doi: 10.1210/me.2010-0362. Epub 2010 Dec 30.

PMID:
21193557
[PubMed - indexed for MEDLINE]
Free PMC Article

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