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Items: 1 to 20 of 80

1.

Adenosine kinase is a new therapeutic target to prevent ischemic neuronal death.

Boison D, Shen HY.

Open Drug Discov J. 2010 Jan 1;2(3):108-118.

2.

Adenosine kinase determines the degree of brain injury after ischemic stroke in mice.

Shen HY, Lusardi TA, Williams-Karnesky RL, Lan JQ, Poulsen DJ, Boison D.

J Cereb Blood Flow Metab. 2011 Jul;31(7):1648-59. doi: 10.1038/jcbfm.2011.30. Epub 2011 Mar 23.

3.

Transgenic overexpression of adenosine kinase aggravates cell death in ischemia.

Pignataro G, Simon RP, Boison D.

J Cereb Blood Flow Metab. 2007 Jan;27(1):1-5. Epub 2006 May 10.

4.

Downregulation of hippocampal adenosine kinase after focal ischemia as potential endogenous neuroprotective mechanism.

Pignataro G, Maysami S, Studer FE, Wilz A, Simon RP, Boison D.

J Cereb Blood Flow Metab. 2008 Jan;28(1):17-23. Epub 2007 Apr 25.

5.
6.

Adenosine kinase, epilepsy and stroke: mechanisms and therapies.

Boison D.

Trends Pharmacol Sci. 2006 Dec;27(12):652-8. Epub 2006 Oct 23. Review.

PMID:
17056128
7.

Adenosine kinase: exploitation for therapeutic gain.

Boison D.

Pharmacol Rev. 2013 Apr 16;65(3):906-43. doi: 10.1124/pr.112.006361. Print 2013 Jul. Review.

8.

Adenosine dysfunction in epilepsy.

Boison D.

Glia. 2012 Aug;60(8):1234-43. doi: 10.1002/glia.22285. Epub 2011 Dec 22. Review.

9.

The adenosine kinase hypothesis of epileptogenesis.

Boison D.

Prog Neurobiol. 2008 Mar;84(3):249-62. doi: 10.1016/j.pneurobio.2007.12.002. Epub 2007 Dec 23. Review.

10.

Astrogliosis in epilepsy leads to overexpression of adenosine kinase, resulting in seizure aggravation.

Fedele DE, Gouder N, Güttinger M, Gabernet L, Scheurer L, Rülicke T, Crestani F, Boison D.

Brain. 2005 Oct;128(Pt 10):2383-95. Epub 2005 Jun 1.

11.

Adenosine kinase as a target for therapeutic antisense strategies in epilepsy.

Theofilas P, Brar S, Stewart KA, Shen HY, Sandau US, Poulsen D, Boison D.

Epilepsia. 2011 Mar;52(3):589-601. doi: 10.1111/j.1528-1167.2010.02947.x. Epub 2011 Jan 28.

12.

Shift of adenosine kinase expression from neurons to astrocytes during postnatal development suggests dual functionality of the enzyme.

Studer FE, Fedele DE, Marowsky A, Schwerdel C, Wernli K, Vogt K, Fritschy JM, Boison D.

Neuroscience. 2006 Sep 29;142(1):125-37. Epub 2006 Jul 20.

PMID:
16859834
13.
14.

Dysregulation of brain adenosine is detrimental to the expression of conditioned freezing but not general Pavlovian learning.

Singer P, Zhang C, Boison D, Yee BK.

Pharmacol Biochem Behav. 2013 Mar;104:80-9. doi: 10.1016/j.pbb.2012.12.012. Epub 2013 Jan 2.

15.

Adenosine augmentation therapies (AATs) for epilepsy: prospect of cell and gene therapies.

Boison D.

Epilepsy Res. 2009 Aug;85(2-3):131-41. doi: 10.1016/j.eplepsyres.2009.03.019. Epub 2009 May 9. Review.

16.

Neuron protection as a therapeutic target in acute ischemic stroke.

Tuttolomondo A, Di Sciacca R, Di Raimondo D, Arnao V, Renda C, Pinto A, Licata G.

Curr Top Med Chem. 2009;9(14):1317-34. Review.

PMID:
19849659
17.

Endogenous neuroprotection: mitochondria as gateways to cerebral preconditioning?

Dirnagl U, Meisel A.

Neuropharmacology. 2008 Sep;55(3):334-44. doi: 10.1016/j.neuropharm.2008.02.017. Epub 2008 Mar 8. Review.

PMID:
18402985
18.

Adenosine kinase is a target for the prediction and prevention of epileptogenesis in mice.

Li T, Ren G, Lusardi T, Wilz A, Lan JQ, Iwasato T, Itohara S, Simon RP, Boison D.

J Clin Invest. 2008 Feb;118(2):571-82. doi: 10.1172/JCI33737.

19.

Therapeutic epilepsy research: from pharmacological rationale to focal adenosine augmentation.

Boison D, Stewart KA.

Biochem Pharmacol. 2009 Dec 15;78(12):1428-37. doi: 10.1016/j.bcp.2009.08.005. Epub 2009 Aug 12. Review.

20.

Adenosine dysfunction in astrogliosis: cause for seizure generation?

Li T, Quan Lan J, Fredholm BB, Simon RP, Boison D.

Neuron Glia Biol. 2007 Nov;3(4):353-66. doi: 10.1017/S1740925X0800015X.

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