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Results: 1 to 20 of 112

1.

Role of toxicogenomics in the development of safe, efficacious and novel anti-microbial therapies.

Sabir JS, Abu-Zinadah OA, Bora RS, Ahmed MM, Saini KS.

Infect Disord Drug Targets. 2013 Jun;13(3):206-14. Review.

PMID:
24087896
[PubMed - indexed for MEDLINE]
2.

The state-of-the-art in predictive toxicogenomics.

Fielden MR, Kolaja KL.

Curr Opin Drug Discov Devel. 2006 Jan;9(1):84-91. Review.

PMID:
16445120
[PubMed - indexed for MEDLINE]
3.
4.

Application of toxicogenomic tools in the drug research and development process.

Fabre N, Anglade I, Vericat JA.

Toxicol Lett. 2009 Apr 10;186(1):13-7.

PMID:
19373985
[PubMed - indexed for MEDLINE]
5.

The Japanese toxicogenomics project: application of toxicogenomics.

Uehara T, Ono A, Maruyama T, Kato I, Yamada H, Ohno Y, Urushidani T.

Mol Nutr Food Res. 2010 Feb;54(2):218-27. doi: 10.1002/mnfr.200900169. Review.

PMID:
20041446
[PubMed - indexed for MEDLINE]
6.

Use of toxicogenomics to understand mechanisms of drug-induced hepatotoxicity during drug discovery and development.

Blomme EA, Yang Y, Waring JF.

Toxicol Lett. 2009 Apr 10;186(1):22-31. doi: 10.1016/j.toxlet.2008.09.017. Epub 2008 Oct 17. Review.

PMID:
18996174
[PubMed - indexed for MEDLINE]
7.

[Development of antituberculous drugs: current status and future prospects].

Tomioka H, Namba K.

Kekkaku. 2006 Dec;81(12):753-74. Review. Japanese.

PMID:
17240921
[PubMed - indexed for MEDLINE]
8.

Toxicogenomics in drug discovery: from preclinical studies to clinical trials.

Yang Y, Blomme EA, Waring JF.

Chem Biol Interact. 2004 Nov 1;150(1):71-85. Review.

PMID:
15522262
[PubMed - indexed for MEDLINE]
9.

SimuGen Ltd: reliable, early prediction of drug toxicity with toxicogenomics, human cell culture and computational models.

Wills Q.

Pharmacogenomics. 2007 Aug;8(8):1081-4. Review.

PMID:
17716240
[PubMed - indexed for MEDLINE]
10.

In vitro transcriptomic prediction of hepatotoxicity for early drug discovery.

Cheng F, Theodorescu D, Schulman IG, Lee JK.

J Theor Biol. 2011 Dec 7;290:27-36. doi: 10.1016/j.jtbi.2011.08.009. Epub 2011 Aug 27.

PMID:
21884709
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Toxicogenomics in drug development.

Guerreiro N, Staedtler F, Grenet O, Kehren J, Chibout SD.

Toxicol Pathol. 2003 Sep-Oct;31(5):471-9. Review.

PMID:
14692614
[PubMed - indexed for MEDLINE]
Free Article
12.

Iconix Biosciences, Inc.

Fielden MR, Halbert DN.

Pharmacogenomics. 2007 Apr;8(4):401-5.

PMID:
17391077
[PubMed - indexed for MEDLINE]
13.

Toxicogenomics in drug discovery and drug development: potential applications and future challenges.

Khor TO, Ibrahim S, Kong AN.

Pharm Res. 2006 Aug;23(8):1659-64. Review.

PMID:
16858654
[PubMed - indexed for MEDLINE]
14.

The discovery and development of proteomic safety biomarkers for the detection of drug-induced liver toxicity.

Amacher DE.

Toxicol Appl Pharmacol. 2010 May 15;245(1):134-42. doi: 10.1016/j.taap.2010.02.011. Epub 2010 Feb 26. Review.

PMID:
20219512
[PubMed - indexed for MEDLINE]
15.

Toxicogenomics in drug discovery and development -- making an impact.

Wills Q, Mitchell C.

Altern Lab Anim. 2009 Sep;37 Suppl 1:33-7.

PMID:
19807202
[PubMed - indexed for MEDLINE]
16.

[Prospects for development of new antituberculous drugs].

Tomioka H.

Kekkaku. 2002 Aug;77(8):573-84. Japanese.

PMID:
12235850
[PubMed - indexed for MEDLINE]
17.

Toxicogenomics in predictive toxicology in drug development.

Suter L, Babiss LE, Wheeldon EB.

Chem Biol. 2004 Feb;11(2):161-71. Review.

PMID:
15123278
[PubMed - indexed for MEDLINE]
Free Article
18.

Gene expression profiling for pharmaceutical safety assessment.

Huby R, Tugwood JD.

Expert Opin Drug Metab Toxicol. 2005 Aug;1(2):247-60. Review.

PMID:
16922640
[PubMed - indexed for MEDLINE]
19.

Toxicogenomics in the pharmaceutical industry: hollow promises or real benefit?

Lühe A, Suter L, Ruepp S, Singer T, Weiser T, Albertini S.

Mutat Res. 2005 Aug 4;575(1-2):102-15. Epub 2005 Apr 25. Review.

PMID:
15924886
[PubMed - indexed for MEDLINE]
20.

New avenues for anti-epileptic drug discovery and development.

Löscher W, Klitgaard H, Twyman RE, Schmidt D.

Nat Rev Drug Discov. 2013 Oct;12(10):757-76. doi: 10.1038/nrd4126. Epub 2013 Sep 20. Review.

PMID:
24052047
[PubMed - indexed for MEDLINE]

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