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Results: 1 to 20 of 106

1.

Defining efficient enzyme-cofactor pairs for bioorthogonal profiling of protein methylation.

Islam K, Chen Y, Wu H, Bothwell IR, Blum GJ, Zeng H, Dong A, Zheng W, Min J, Deng H, Luo M.

Proc Natl Acad Sci U S A. 2013 Oct 15;110(42):16778-83. doi: 10.1073/pnas.1216365110. Epub 2013 Sep 30.

PMID:
24082136
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Bioorthogonal profiling of protein methylation using azido derivative of S-adenosyl-L-methionine.

Islam K, Bothwell I, Chen Y, Sengelaub C, Wang R, Deng H, Luo M.

J Am Chem Soc. 2012 Apr 4;134(13):5909-15. doi: 10.1021/ja2118333. Epub 2012 Mar 26.

PMID:
22404544
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Profiling substrates of protein arginine N-methyltransferase 3 with S-adenosyl-L-methionine analogues.

Guo H, Wang R, Zheng W, Chen Y, Blum G, Deng H, Luo M.

ACS Chem Biol. 2014 Feb 21;9(2):476-84. doi: 10.1021/cb4008259. Epub 2013 Dec 9.

PMID:
24320160
[PubMed - indexed for MEDLINE]
4.

Formulating a fluorogenic assay to evaluate S-adenosyl-L-methionine analogues as protein methyltransferase cofactors.

Wang R, Ibáñez G, Islam K, Zheng W, Blum G, Sengelaub C, Luo M.

Mol Biosyst. 2011 Nov;7(11):2970-81. doi: 10.1039/c1mb05230f. Epub 2011 Aug 24.

PMID:
21866297
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Profiling genome-wide chromatin methylation with engineered posttranslation apparatus within living cells.

Wang R, Islam K, Liu Y, Zheng W, Tang H, Lailler N, Blum G, Deng H, Luo M.

J Am Chem Soc. 2013 Jan 23;135(3):1048-56. doi: 10.1021/ja309412s. Epub 2013 Jan 10.

PMID:
23244065
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Expanding cofactor repertoire of protein lysine methyltransferase for substrate labeling.

Islam K, Zheng W, Yu H, Deng H, Luo M.

ACS Chem Biol. 2011 Jul 15;6(7):679-84. doi: 10.1021/cb2000567. Epub 2011 Apr 22.

PMID:
21495674
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Bioorthogonal profiling of protein methylation (BPPM) using an azido analog of S-adenosyl-L-methionine.

Blum G, Islam K, Luo M.

Curr Protoc Chem Biol. 2013;5(1):45-66.

PMID:
23667794
[PubMed - in process]
Free PMC Article
8.

Labeling substrates of protein arginine methyltransferase with engineered enzymes and matched S-adenosyl-L-methionine analogues.

Wang R, Zheng W, Yu H, Deng H, Luo M.

J Am Chem Soc. 2011 May 25;133(20):7648-51. doi: 10.1021/ja2006719. Epub 2011 May 3.

PMID:
21539310
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

A journey toward Bioorthogonal Profiling of Protein Methylation inside living cells.

Wang R, Luo M.

Curr Opin Chem Biol. 2013 Oct;17(5):729-37. doi: 10.1016/j.cbpa.2013.08.007. Epub 2013 Sep 12. Review.

PMID:
24035694
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

An enzyme-coupled ultrasensitive luminescence assay for protein methyltransferases.

Ibáñez G, McBean JL, Astudillo YM, Luo M.

Anal Biochem. 2010 Jun 15;401(2):203-10. doi: 10.1016/j.ab.2010.03.010. Epub 2010 Mar 12.

PMID:
20227379
[PubMed - indexed for MEDLINE]
11.

A kinetic study of human protein arginine N-methyltransferase 6 reveals a distributive mechanism.

Lakowski TM, Frankel A.

J Biol Chem. 2008 Apr 11;283(15):10015-25. doi: 10.1074/jbc.M710176200. Epub 2008 Feb 8.

PMID:
18263580
[PubMed - indexed for MEDLINE]
Free Article
12.

Identification and characterization of a highly conserved crenarchaeal protein lysine methyltransferase with broad substrate specificity.

Chu Y, Zhang Z, Wang Q, Luo Y, Huang L.

J Bacteriol. 2012 Dec;194(24):6917-26. doi: 10.1128/JB.01535-12. Epub 2012 Oct 19.

PMID:
23086207
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

A chemical method for labeling lysine methyltransferase substrates.

Binda O, Boyce M, Rush JS, Palaniappan KK, Bertozzi CR, Gozani O.

Chembiochem. 2011 Jan 24;12(2):330-4. doi: 10.1002/cbic.201000433. Epub 2010 Nov 17.

PMID:
21243721
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Design of allele-specific protein methyltransferase inhibitors.

Lin Q, Jiang F, Schultz PG, Gray NS.

J Am Chem Soc. 2001 Nov 28;123(47):11608-13.

PMID:
11716715
[PubMed - indexed for MEDLINE]
15.

G9a interacts with Snail and is critical for Snail-mediated E-cadherin repression in human breast cancer.

Dong C, Wu Y, Yao J, Wang Y, Yu Y, Rychahou PG, Evers BM, Zhou BP.

J Clin Invest. 2012 Apr 2;122(4):1469-86. doi: 10.1172/JCI57349. Epub 2012 Mar 12.

PMID:
22406531
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Substrate specificity and kinetic mechanism of mammalian G9a histone H3 methyltransferase.

Patnaik D, Chin HG, Estève PO, Benner J, Jacobsen SE, Pradhan S.

J Biol Chem. 2004 Dec 17;279(51):53248-58. Epub 2004 Oct 14.

PMID:
15485804
[PubMed - indexed for MEDLINE]
Free Article
17.

A high throughput scintillation proximity imaging assay for protein methyltransferases.

Ibanez G, Shum D, Blum G, Bhinder B, Radu C, Antczak C, Luo M, Djaballah H.

Comb Chem High Throughput Screen. 2012 Jun 1;15(5):359-71.

PMID:
22256970
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

A subset of the histone H3 lysine 9 methyltransferases Suv39h1, G9a, GLP, and SETDB1 participate in a multimeric complex.

Fritsch L, Robin P, Mathieu JR, Souidi M, Hinaux H, Rougeulle C, Harel-Bellan A, Ameyar-Zazoua M, Ait-Si-Ali S.

Mol Cell. 2010 Jan 15;37(1):46-56. doi: 10.1016/j.molcel.2009.12.017.

PMID:
20129054
[PubMed - indexed for MEDLINE]
Free Article
19.

Crystal structures of the human histone H4K20 methyltransferases SUV420H1 and SUV420H2.

Wu H, Siarheyeva A, Zeng H, Lam R, Dong A, Wu XH, Li Y, Schapira M, Vedadi M, Min J.

FEBS Lett. 2013 Nov 29;587(23):3859-68.

PMID:
24396869
[PubMed - indexed for MEDLINE]
Free Article
20.

Se-adenosyl-L-selenomethionine cofactor analogue as a reporter of protein methylation.

Bothwell IR, Islam K, Chen Y, Zheng W, Blum G, Deng H, Luo M.

J Am Chem Soc. 2012 Sep 12;134(36):14905-12. doi: 10.1021/ja304782r. Epub 2012 Sep 4.

PMID:
22917021
[PubMed - indexed for MEDLINE]
Free PMC Article
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