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Results: 1 to 20 of 105

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BMP signaling controls muscle mass.

Sartori R, Schirwis E, Blaauw B, Bortolanza S, Zhao J, Enzo E, Stantzou A, Mouisel E, Toniolo L, Ferry A, Stricker S, Goldberg AL, Dupont S, Piccolo S, Amthor H, Sandri M.

Nat Genet. 2013 Nov;45(11):1309-18. doi: 10.1038/ng.2772. Epub 2013 Sep 29.


Involvement of BMPs/Smad signaling pathway in mechanical response in osteoblasts.

Wang L, Zhang X, Guo Y, Chen X, Li R, Liu L, Shi C, Guo C, Zhang Y.

Cell Physiol Biochem. 2010;26(6):1093-102. doi: 10.1159/000323987. Epub 2011 Jan 4.


BMP canonical Smad signaling through Smad1 and Smad5 is required for endochondral bone formation.

Retting KN, Song B, Yoon BS, Lyons KM.

Development. 2009 Apr;136(7):1093-104. doi: 10.1242/dev.029926. Epub 2009 Feb 18.


Inhibition of mTORC1 kinase activates Smads 1 and 5 but not Smad8 in human prostate cancer cells, mediating cytostatic response to rapamycin.

Wahdan-Alaswad RS, Bane KL, Song K, Shola DT, Garcia JA, Danielpour D.

Mol Cancer Res. 2012 Jun;10(6):821-33. doi: 10.1158/1541-7786.MCR-11-0615. Epub 2012 Mar 27.


Specific control of BMP signaling and mesenchymal differentiation by cytoplasmic phosphatase PPM1H.

Shen T, Sun C, Zhang Z, Xu N, Duan X, Feng XH, Lin X.

Cell Res. 2014 Jun;24(6):727-41. doi: 10.1038/cr.2014.48. Epub 2014 Apr 15.


The bone morphogenetic protein axis is a positive regulator of skeletal muscle mass.

Winbanks CE, Chen JL, Qian H, Liu Y, Bernardo BC, Beyer C, Watt KI, Thomson RE, Connor T, Turner BJ, McMullen JR, Larsson L, McGee SL, Harrison CA, Gregorevic P.

J Cell Biol. 2013 Oct 28;203(2):345-57. doi: 10.1083/jcb.201211134. Epub 2013 Oct 21.


Transcriptional factors smad1 and smad9 act redundantly to mediate zebrafish ventral specification downstream of smad5.

Wei CY, Wang HP, Zhu ZY, Sun YH.

J Biol Chem. 2014 Mar 7;289(10):6604-18. doi: 10.1074/jbc.M114.549758. Epub 2014 Jan 31.


An atypical canonical bone morphogenetic protein (BMP) signaling pathway regulates Msh homeobox 1 (Msx1) expression during odontogenesis.

Yang G, Yuan G, Ye W, Cho KW, Chen Y.

J Biol Chem. 2014 Nov 7;289(45):31492-502. doi: 10.1074/jbc.M114.600064. Epub 2014 Oct 1.


BMP/Smad signaling is not enhanced in Hfe-deficient mice despite increased Bmp6 expression.

Kautz L, Meynard D, Besson-Fournier C, Darnaud V, Al Saati T, Coppin H, Roth MP.

Blood. 2009 Sep 17;114(12):2515-20. doi: 10.1182/blood-2009-02-206771. Epub 2009 Jul 21.


Canonical BMP signaling is dispensable for hematopoietic stem cell function in both adult and fetal liver hematopoiesis, but essential to preserve colon architecture.

Singbrant S, Karlsson G, Ehinger M, Olsson K, Jaako P, Miharada K, Stadtfeld M, Graf T, Karlsson S.

Blood. 2010 Jun 10;115(23):4689-98. doi: 10.1182/blood-2009-05-220988. Epub 2010 Apr 6.


The bone morphogenetic protein receptor-1A pathway is required for lactogenic differentiation of mammary epithelial cells in vitro.

Perotti C, Karayazi O, Moffat S, Shemanko CS.

In Vitro Cell Dev Biol Anim. 2012 Jun;48(6):377-84. doi: 10.1007/s11626-012-9522-z. Epub 2012 Jun 23.


Ubc9 promotes the stability of Smad4 and the nuclear accumulation of Smad1 in osteoblast-like Saos-2 cells.

Shimada K, Suzuki N, Ono Y, Tanaka K, Maeno M, Ito K.

Bone. 2008 May;42(5):886-93. doi: 10.1016/j.bone.2008.01.009. Epub 2008 Feb 7.


Genome-wide mapping of SMAD target genes reveals the role of BMP signaling in embryonic stem cell fate determination.

Fei T, Xia K, Li Z, Zhou B, Zhu S, Chen H, Zhang J, Chen Z, Xiao H, Han JD, Chen YG.

Genome Res. 2010 Jan;20(1):36-44. doi: 10.1101/gr.092114.109. Epub 2009 Nov 19.


Dysregulated bone morphogenetic protein signaling in monocrotaline-induced pulmonary arterial hypertension.

Morty RE, Nejman B, Kwapiszewska G, Hecker M, Zakrzewicz A, Kouri FM, Peters DM, Dumitrascu R, Seeger W, Knaus P, Schermuly RT, Eickelberg O.

Arterioscler Thromb Vasc Biol. 2007 May;27(5):1072-8. Epub 2007 Mar 8.


c-Abl promotes osteoblast expansion by differentially regulating canonical and non-canonical BMP pathways and p16INK4a expression.

Kua HY, Liu H, Leong WF, Li L, Jia D, Ma G, Hu Y, Wang X, Chau JF, Chen YG, Mishina Y, Boast S, Yeh J, Xia L, Chen GQ, He L, Goff SP, Li B.

Nat Cell Biol. 2012 Jun 24;14(7):727-37. doi: 10.1038/ncb2528.


Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1, and Atoh8 in the mouse liver.

Kautz L, Meynard D, Monnier A, Darnaud V, Bouvet R, Wang RH, Deng C, Vaulont S, Mosser J, Coppin H, Roth MP.

Blood. 2008 Aug 15;112(4):1503-9. doi: 10.1182/blood-2008-03-143354. Epub 2008 Jun 6.


Conditional deletion of Smad1 and Smad5 in somatic cells of male and female gonads leads to metastatic tumor development in mice.

Pangas SA, Li X, Umans L, Zwijsen A, Huylebroeck D, Gutierrez C, Wang D, Martin JF, Jamin SP, Behringer RR, Robertson EJ, Matzuk MM.

Mol Cell Biol. 2008 Jan;28(1):248-57. Epub 2007 Oct 29.


Bone morphogenetic protein-7 expression and activity in the human adult normal kidney is predominantly localized to the distal nephron.

Wetzel P, Haag J, Câmpean V, Goldschmeding R, Atalla A, Amann K, Aigner T.

Kidney Int. 2006 Aug;70(4):717-23.

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