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Items: 1 to 20 of 137

1.

Novel CD47: SIRPα dependent mechanism for the activation of STAT3 in antigen-presenting cell.

Toledano N, Gur-Wahnon D, Ben-Yehuda A, Rachmilewitz J.

PLoS One. 2013 Sep 20;8(9):e75595. doi: 10.1371/journal.pone.0075595. eCollection 2013.

2.

"Velcro" engineering of high affinity CD47 ectodomain as signal regulatory protein α (SIRPα) antagonists that enhance antibody-dependent cellular phagocytosis.

Ho CC, Guo N, Sockolosky JT, Ring AM, Weiskopf K, Özkan E, Mori Y, Weissman IL, Garcia KC.

J Biol Chem. 2015 May 15;290(20):12650-63. doi: 10.1074/jbc.M115.648220. Epub 2015 Apr 2.

3.

The interaction between signal regulatory protein alpha (SIRPα) and CD47: structure, function, and therapeutic target.

Barclay AN, Van den Berg TK.

Annu Rev Immunol. 2014;32:25-50. doi: 10.1146/annurev-immunol-032713-120142. Epub 2013 Nov 6. Review.

PMID:
24215318
4.

Functions and molecular mechanisms of the CD47-SIRPalpha signalling pathway.

Matozaki T, Murata Y, Okazawa H, Ohnishi H.

Trends Cell Biol. 2009 Feb;19(2):72-80. doi: 10.1016/j.tcb.2008.12.001. Epub 2009 Jan 12. Review.

PMID:
19144521
5.
6.

Lack of CD47 impairs bone cell differentiation and results in an osteopenic phenotype in vivo due to impaired signal regulatory protein α (SIRPα) signaling.

Koskinen C, Persson E, Baldock P, Stenberg Å, Boström I, Matozaki T, Oldenborg PA, Lundberg P.

J Biol Chem. 2013 Oct 11;288(41):29333-44. doi: 10.1074/jbc.M113.494591. Epub 2013 Aug 29.

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8.

Role for CD47-SIRPalpha signaling in xenograft rejection by macrophages.

Ide K, Wang H, Tahara H, Liu J, Wang X, Asahara T, Sykes M, Yang YG, Ohdan H.

Proc Natl Acad Sci U S A. 2007 Mar 20;104(12):5062-6. Epub 2007 Mar 12.

9.

Functional CD47/signal regulatory protein alpha (SIRP(alpha)) interaction is required for optimal human T- and natural killer- (NK) cell homeostasis in vivo.

Legrand N, Huntington ND, Nagasawa M, Bakker AQ, Schotte R, Strick-Marchand H, de Geus SJ, Pouw SM, Böhne M, Voordouw A, Weijer K, Di Santo JP, Spits H.

Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13224-9. doi: 10.1073/pnas.1101398108. Epub 2011 Jul 25.

10.

Polymorphisms in the human inhibitory signal-regulatory protein α do not affect binding to its ligand CD47.

Hatherley D, Lea SM, Johnson S, Barclay AN.

J Biol Chem. 2014 Apr 4;289(14):10024-8. doi: 10.1074/jbc.M114.550558. Epub 2014 Feb 18.

11.

The CD47-SIRPα signalling system: its physiological roles and therapeutic application.

Murata Y, Kotani T, Ohnishi H, Matozaki T.

J Biochem. 2014 Jun;155(6):335-44. doi: 10.1093/jb/mvu017. Epub 2014 Mar 12. Review.

PMID:
24627525
12.

Dual regulation of SIRPalpha phosphorylation by integrins and CD47.

Johansen ML, Brown EJ.

J Biol Chem. 2007 Aug 17;282(33):24219-30. Epub 2007 Jun 21.

13.

Myelin down-regulates myelin phagocytosis by microglia and macrophages through interactions between CD47 on myelin and SIRPα (signal regulatory protein-α) on phagocytes.

Gitik M, Liraz-Zaltsman S, Oldenborg PA, Reichert F, Rotshenker S.

J Neuroinflammation. 2011 Mar 15;8:24. doi: 10.1186/1742-2094-8-24.

14.

Evaluation of normal and neoplastic human mast cells for expression of CD172a (SIRPalpha), CD47, and SHP-1.

Florian S, Ghannadan M, Mayerhofer M, Aichberger KJ, Hauswirth AW, Schernthaner GH, Printz D, Fritsch G, Böhm A, Sonneck K, Krauth MT, Müller MR, Sillaber C, Sperr WR, Bühring HJ, Valent P.

J Leukoc Biol. 2005 Jun;77(6):984-92. Epub 2005 Mar 22.

15.

Negative regulation of phagocytosis in macrophages by the CD47-SHPS-1 system.

Okazawa H, Motegi S, Ohyama N, Ohnishi H, Tomizawa T, Kaneko Y, Oldenborg PA, Ishikawa O, Matozaki T.

J Immunol. 2005 Feb 15;174(4):2004-11.

16.

Loss of Cell Surface CD47 Clustering Formation and Binding Avidity to SIRPα Facilitate Apoptotic Cell Clearance by Macrophages.

Lv Z, Bian Z, Shi L, Niu S, Ha B, Tremblay A, Li L, Zhang X, Paluszynski J, Liu M, Zen K, Liu Y.

J Immunol. 2015 Jul 15;195(2):661-71. doi: 10.4049/jimmunol.1401719. Epub 2015 Jun 17.

PMID:
26085683
17.

Autoimmune animal models in the analysis of the CD47-SIRPα signaling pathway.

Murata Y, Saito Y, Kaneko T, Kotani T, Kaneko Y, Ohnishi H, Matozaki T.

Methods. 2014 Jan 15;65(2):254-9. doi: 10.1016/j.ymeth.2013.09.016. Epub 2013 Oct 1.

PMID:
24091004
18.

The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors.

Willingham SB, Volkmer JP, Gentles AJ, Sahoo D, Dalerba P, Mitra SS, Wang J, Contreras-Trujillo H, Martin R, Cohen JD, Lovelace P, Scheeren FA, Chao MP, Weiskopf K, Tang C, Volkmer AK, Naik TJ, Storm TA, Mosley AR, Edris B, Schmid SM, Sun CK, Chua MS, Murillo O, Rajendran P, Cha AC, Chin RK, Kim D, Adorno M, Raveh T, Tseng D, Jaiswal S, Enger PØ, Steinberg GK, Li G, So SK, Majeti R, Harsh GR, van de Rijn M, Teng NN, Sunwoo JB, Alizadeh AA, Clarke MF, Weissman IL.

Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):6662-7. doi: 10.1073/pnas.1121623109. Epub 2012 Mar 26.

19.

The role of cis dimerization of signal regulatory protein alpha (SIRPalpha) in binding to CD47.

Lee WY, Weber DA, Laur O, Stowell SR, McCall I, Andargachew R, Cummings RD, Parkos CA.

J Biol Chem. 2010 Dec 3;285(49):37953-63. doi: 10.1074/jbc.M110.180018. Epub 2010 Sep 7.

20.
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