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Results: 1 to 20 of 95

1.

Human memory Helios- FOXP3+ regulatory T cells (Tregs) encompass induced Tregs that express Aiolos and respond to IL-1β by downregulating their suppressor functions.

Raffin C, Pignon P, Celse C, Debien E, Valmori D, Ayyoub M.

J Immunol. 2013 Nov 1;191(9):4619-27. doi: 10.4049/jimmunol.1301378. Epub 2013 Sep 25.

PMID:
24068664
[PubMed - indexed for MEDLINE]
Free Article
2.

Helios+ and Helios- cells coexist within the natural FOXP3+ T regulatory cell subset in humans.

Himmel ME, MacDonald KG, Garcia RV, Steiner TS, Levings MK.

J Immunol. 2013 Mar 1;190(5):2001-8. doi: 10.4049/jimmunol.1201379. Epub 2013 Jan 28.

PMID:
23359504
[PubMed - indexed for MEDLINE]
Free Article
3.

Helios induces epigenetic silencing of IL2 gene expression in regulatory T cells.

Baine I, Basu S, Ames R, Sellers RS, Macian F.

J Immunol. 2013 Feb 1;190(3):1008-16. doi: 10.4049/jimmunol.1200792. Epub 2012 Dec 28.

PMID:
23275607
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Expanded subpopulation of FoxP3+ T regulatory cells in renal cell carcinoma co-express Helios, indicating they could be derived from natural but not induced Tregs.

Elkord E, Sharma S, Burt DJ, Hawkins RE.

Clin Immunol. 2011 Sep;140(3):218-22. doi: 10.1016/j.clim.2011.04.014. Epub 2011 Apr 29.

PMID:
21570917
[PubMed - indexed for MEDLINE]
5.

Oligodeoxynucleotides stabilize Helios-expressing Foxp3+ human T regulatory cells during in vitro expansion.

Kim YC, Bhairavabhotla R, Yoon J, Golding A, Thornton AM, Tran DQ, Shevach EM.

Blood. 2012 Mar 22;119(12):2810-8. doi: 10.1182/blood-2011-09-377895. Epub 2012 Jan 31.

PMID:
22294730
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Foxp3+ Helios+ regulatory T cells are expanded in active systemic lupus erythematosus.

Alexander T, Sattler A, Templin L, Kohler S, Groß C, Meisel A, Sawitzki B, Burmester GR, Arnold R, Radbruch A, Thiel A, Hiepe F.

Ann Rheum Dis. 2013 Sep 1;72(9):1549-58. doi: 10.1136/annrheumdis-2012-202216. Epub 2012 Dec 21.

PMID:
23264341
[PubMed - indexed for MEDLINE]
7.

Expression of Helios, an Ikaros transcription factor family member, differentiates thymic-derived from peripherally induced Foxp3+ T regulatory cells.

Thornton AM, Korty PE, Tran DQ, Wohlfert EA, Murray PE, Belkaid Y, Shevach EM.

J Immunol. 2010 Apr 1;184(7):3433-41. doi: 10.4049/jimmunol.0904028. Epub 2010 Feb 24.

PMID:
20181882
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Differential control of Helios(+/-) Treg development by monocyte subsets through disparate inflammatory cytokines.

Zhong H, Yazdanbakhsh K.

Blood. 2013 Mar 28;121(13):2494-502. doi: 10.1182/blood-2012-11-469122. Epub 2013 Jan 30.

PMID:
23365462
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Helios expression is a marker of T cell activation and proliferation.

Akimova T, Beier UH, Wang L, Levine MH, Hancock WW.

PLoS One. 2011;6(8):e24226. doi: 10.1371/journal.pone.0024226. Epub 2011 Aug 30.

PMID:
21918685
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Ex vivo IL-1 receptor type I expression in human CD4+ T cells identifies an early intermediate in the differentiation of Th17 from FOXP3+ naive regulatory T cells.

Raffin C, Raimbaud I, Valmori D, Ayyoub M.

J Immunol. 2011 Nov 15;187(10):5196-202. doi: 10.4049/jimmunol.1101742. Epub 2011 Oct 12.

PMID:
21998454
[PubMed - indexed for MEDLINE]
Free Article
11.

A role for the transcription factor Helios in human CD4(+)CD25(+) regulatory T cells.

Getnet D, Grosso JF, Goldberg MV, Harris TJ, Yen HR, Bruno TC, Durham NM, Hipkiss EL, Pyle KJ, Wada S, Pan F, Pardoll DM, Drake CG.

Mol Immunol. 2010 Apr;47(7-8):1595-600. doi: 10.1016/j.molimm.2010.02.001. Epub 2010 Mar 11.

PMID:
20226531
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

IL-1beta and IL-2 convert human Treg into T(H)17 cells.

Deknuydt F, Bioley G, Valmori D, Ayyoub M.

Clin Immunol. 2009 May;131(2):298-307. doi: 10.1016/j.clim.2008.12.008. Epub 2009 Feb 11.

PMID:
19211307
[PubMed - indexed for MEDLINE]
13.

The time is crucial for ex vivo expansion of T regulatory cells for therapy.

Marek N, Bieniaszewska M, Krzystyniak A, Juścińska J, Myśliwska J, Witkowski P, Hellmann A, Trzonkowski P.

Cell Transplant. 2011;20(11-12):1747-58. doi: 10.3727/096368911X566217. Epub 2011 Apr 1.

PMID:
21457615
[PubMed - indexed for MEDLINE]
14.

FoxP3, Helios, and SATB1: roles and relationships in regulatory T cells.

Grzanka J, Leveson-Gower D, Golab K, Wang XJ, Marek-Trzonkowska N, Krzystyniak A, Wardowska A, Mills JM, Trzonkowski P, Witkowski P.

Int Immunopharmacol. 2013 Jul;16(3):343-7. doi: 10.1016/j.intimp.2013.02.004. Epub 2013 Feb 18. Review.

PMID:
23428911
[PubMed - indexed for MEDLINE]
15.

Foxp3+ Treg expanded from patients with established diabetes reduce Helios expression while retaining normal function compared to healthy individuals.

Du W, Shen YW, Lee WH, Wang D, Paz S, Kandeel F, Liu CP.

PLoS One. 2013;8(2):e56209. doi: 10.1371/journal.pone.0056209. Epub 2013 Feb 11.

PMID:
23409157
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Comparative analyses of regulatory T cell subsets in patients with hepatocellular carcinoma: a crucial role of CD25(-) FOXP3(-) T cells.

Kakita N, Kanto T, Itose I, Kuroda S, Inoue M, Matsubara T, Higashitani K, Miyazaki M, Sakakibara M, Hiramatsu N, Takehara T, Kasahara A, Hayashi N.

Int J Cancer. 2012 Dec 1;131(11):2573-83. doi: 10.1002/ijc.27535. Epub 2012 Mar 29.

PMID:
22419479
[PubMed - indexed for MEDLINE]
17.

Differential expression of CCR7 defines two distinct subsets of human memory CD4+CD25+ Tregs.

Tosello V, Odunsi K, Souleimanian NE, Lele S, Shrikant P, Old LJ, Valmori D, Ayyoub M.

Clin Immunol. 2008 Mar;126(3):291-302. doi: 10.1016/j.clim.2007.11.008. Epub 2007 Dec 31.

PMID:
18166500
[PubMed - indexed for MEDLINE]
18.

Characterization of protective human CD4CD25 FOXP3 regulatory T cells generated with IL-2, TGF-β and retinoic acid.

Lu L, Zhou X, Wang J, Zheng SG, Horwitz DA.

PLoS One. 2010 Dec 17;5(12):e15150. doi: 10.1371/journal.pone.0015150.

PMID:
21179414
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Stimulation of α7 nicotinic acetylcholine receptor by nicotine increases suppressive capacity of naturally occurring CD4+CD25+ regulatory T cells in mice in vitro.

Wang DW, Zhou RB, Yao YM, Zhu XM, Yin YM, Zhao GJ, Dong N, Sheng ZY.

J Pharmacol Exp Ther. 2010 Dec;335(3):553-61. doi: 10.1124/jpet.110.169961. Epub 2010 Sep 15.

PMID:
20843956
[PubMed - indexed for MEDLINE]
Free Article
20.

Expression of Helios in peripherally induced Foxp3+ regulatory T cells.

Gottschalk RA, Corse E, Allison JP.

J Immunol. 2012 Feb 1;188(3):976-80. doi: 10.4049/jimmunol.1102964. Epub 2011 Dec 23.

PMID:
22198953
[PubMed - indexed for MEDLINE]
Free Article

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