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Results: 1 to 20 of 203

1.

Development of novel 123I-labeled pyridyl benzofuran derivatives for SPECT imaging of β-amyloid plaques in Alzheimer's disease.

Ono M, Cheng Y, Kimura H, Watanabe H, Matsumura K, Yoshimura M, Iikuni S, Okamoto Y, Ihara M, Takahashi R, Saji H.

PLoS One. 2013 Sep 13;8(9):e74104. doi: 10.1371/journal.pone.0074104. eCollection 2013.

PMID:
24058519
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Technetium-99m labeled pyridyl benzofuran derivatives as single photon emission computed tomography imaging probes for β-amyloid plaques in Alzheimer's brains.

Cheng Y, Ono M, Kimura H, Ueda M, Saji H.

J Med Chem. 2012 Mar 8;55(5):2279-86. doi: 10.1021/jm201513c. Epub 2012 Feb 24.

PMID:
22364445
[PubMed - indexed for MEDLINE]
3.

A novel 18F-labeled pyridyl benzofuran derivative for imaging of β-amyloid plaques in Alzheimer's brains.

Cheng Y, Ono M, Kimura H, Kagawa S, Nishii R, Saji H.

Bioorg Med Chem Lett. 2010 Oct 15;20(20):6141-4. doi: 10.1016/j.bmcl.2010.08.016. Epub 2010 Aug 8.

PMID:
20817524
[PubMed - indexed for MEDLINE]
4.

Radioiodinated benzimidazole derivatives as single photon emission computed tomography probes for imaging of β-amyloid plaques in Alzheimer's disease.

Cui M, Ono M, Kimura H, Kawashima H, Liu BL, Saji H.

Nucl Med Biol. 2011 Apr;38(3):313-20. doi: 10.1016/j.nucmedbio.2010.09.012. Epub 2010 Dec 3.

PMID:
21492779
[PubMed - indexed for MEDLINE]
5.

Synthesis and evaluation of novel chalcone derivatives with (99m)Tc/Re complexes as potential probes for detection of β-amyloid plaques.

Ono M, Ikeoka R, Watanabe H, Kimura H, Fuchigami T, Haratake M, Saji H, Nakayama M.

ACS Chem Neurosci. 2010 Sep 15;1(9):598-607. doi: 10.1021/cn100042d. Epub 2010 Jul 8.

PMID:
22778849
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Diphenylpropynone derivatives as probes for imaging β-amyloid plaques in Alzheimer's brains.

Ono M, Watanabe H, Watanabe R, Haratake M, Nakayama M, Saji H.

Bioorg Med Chem Lett. 2011 Jan 1;21(1):117-20. doi: 10.1016/j.bmcl.2010.11.058. Epub 2010 Nov 23.

PMID:
21145738
[PubMed - indexed for MEDLINE]
7.

Novel radioiodinated aurones as probes for SPECT imaging of beta-amyloid plaques in the brain.

Maya Y, Ono M, Watanabe H, Haratake M, Saji H, Nakayama M.

Bioconjug Chem. 2009 Jan;20(1):95-101. doi: 10.1021/bc8003292.

PMID:
19072219
[PubMed - indexed for MEDLINE]
8.

Synthesis and evaluation of benzofuran-2-yl(phenyl)methanone derivatives as ligands for β-amyloid plaques.

Cui M, Ono M, Kimura H, Liu B, Saji H.

Bioorg Med Chem. 2011 Jul 1;19(13):4148-53. doi: 10.1016/j.bmc.2011.04.049. Epub 2011 May 3.

PMID:
21622003
[PubMed - indexed for MEDLINE]
9.

Novel 18F-labeled benzofuran derivatives with improved properties for positron emission tomography (PET) imaging of β-amyloid plaques in Alzheimer's brains.

Ono M, Cheng Y, Kimura H, Cui M, Kagawa S, Nishii R, Saji H.

J Med Chem. 2011 Apr 28;54(8):2971-9. doi: 10.1021/jm200057u. Epub 2011 Mar 23.

PMID:
21428407
[PubMed - indexed for MEDLINE]
10.

Characterization of IMPY as a potential imaging agent for beta-amyloid plaques in double transgenic PSAPP mice.

Kung MP, Hou C, Zhuang ZP, Cross AJ, Maier DL, Kung HF.

Eur J Nucl Med Mol Imaging. 2004 Aug;31(8):1136-45. Epub 2004 Mar 9.

PMID:
15007564
[PubMed - indexed for MEDLINE]
11.

A dual fluorinated and iodinated radiotracer for PET and SPECT imaging of β-amyloid plaques in the brain.

Watanabe H, Ono M, Kimura H, Kagawa S, Nishii R, Fuchigami T, Haratake M, Nakayama M, Saji H.

Bioorg Med Chem Lett. 2011 Nov 1;21(21):6519-22. doi: 10.1016/j.bmcl.2011.08.063. Epub 2011 Aug 24.

PMID:
21920750
[PubMed - indexed for MEDLINE]
12.

(E)-5-styryl-1H-indole and (E)-6-styrylquinoline derivatives serve as probes for β-amyloid plaques.

Yang Y, Jia HM, Liu BL.

Molecules. 2012 Apr 10;17(4):4252-65. doi: 10.3390/molecules17044252.

PMID:
22491675
[PubMed - indexed for MEDLINE]
Free Article
13.

Novel ¹⁸F-labeled benzoxazole derivatives as potential positron emission tomography probes for imaging of cerebral β-amyloid plaques in Alzheimer's disease.

Cui M, Ono M, Kimura H, Ueda M, Nakamoto Y, Togashi K, Okamoto Y, Ihara M, Takahashi R, Liu B, Saji H.

J Med Chem. 2012 Nov 8;55(21):9136-45. doi: 10.1021/jm300251n. Epub 2012 Jun 12.

PMID:
22690944
[PubMed - indexed for MEDLINE]
14.

Synthesis and evaluation of two 18F-labeled 6-iodo-2-(4'-N,N-dimethylamino)phenylimidazo[1,2-a]pyridine derivatives as prospective radioligands for beta-amyloid in Alzheimer's disease.

Cai L, Chin FT, Pike VW, Toyama H, Liow JS, Zoghbi SS, Modell K, Briard E, Shetty HU, Sinclair K, Donohue S, Tipre D, Kung MP, Dagostin C, Widdowson DA, Green M, Gao W, Herman MM, Ichise M, Innis RB.

J Med Chem. 2004 Apr 22;47(9):2208-18.

PMID:
15084119
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

IMPY: an improved thioflavin-T derivative for in vivo labeling of beta-amyloid plaques.

Kung MP, Hou C, Zhuang ZP, Zhang B, Skovronsky D, Trojanowski JQ, Lee VM, Kung HF.

Brain Res. 2002 Nov 29;956(2):202-10.

PMID:
12445687
[PubMed - indexed for MEDLINE]
16.

Novel quinoxaline derivatives for in vivo imaging of β-amyloid plaques in the brain.

Cui M, Ono M, Kimura H, Liu B, Saji H.

Bioorg Med Chem Lett. 2011 Jul 15;21(14):4193-6. doi: 10.1016/j.bmcl.2011.05.079. Epub 2011 May 27.

PMID:
21684159
[PubMed - indexed for MEDLINE]
17.

Synthesis and biological evaluation of 18F-labled 2-phenylindole derivatives as PET imaging probes for β-amyloid plaques.

Fu H, Yu L, Cui M, Zhang J, Zhang X, Li Z, Wang X, Jia J, Yang Y, Yu P, Jia H, Liu B.

Bioorg Med Chem. 2013 Jul 1;21(13):3708-14. doi: 10.1016/j.bmc.2013.04.028. Epub 2013 Apr 24.

PMID:
23673220
[PubMed - indexed for MEDLINE]
18.

99mTc/Re complexes based on flavone and aurone as SPECT probes for imaging cerebral β-amyloid plaques.

Ono M, Ikeoka R, Watanabe H, Kimura H, Fuchigami T, Haratake M, Saji H, Nakayama M.

Bioorg Med Chem Lett. 2010 Oct 1;20(19):5743-8. doi: 10.1016/j.bmcl.2010.08.004. Epub 2010 Aug 6.

PMID:
20797860
[PubMed - indexed for MEDLINE]
19.

Preclinical properties of 18F-AV-45: a PET agent for Abeta plaques in the brain.

Choi SR, Golding G, Zhuang Z, Zhang W, Lim N, Hefti F, Benedum TE, Kilbourn MR, Skovronsky D, Kung HF.

J Nucl Med. 2009 Nov;50(11):1887-94. doi: 10.2967/jnumed.109.065284. Epub 2009 Oct 16.

PMID:
19837759
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

99mTc-Labeled pyridyl benzofuran derivatives to target β-amyloid plaques.

Chopra A.

Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004-2013.
2012 Jul 11 [updated 2012 Aug 16].

PMID:
22896863
[PubMed]
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