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Results: 1 to 20 of 103

1.

Mitochondrial mutations and ageing: can mitochondrial deletion mutants accumulate via a size based replication advantage?

Kowald A, Dawson M, Kirkwood TB.

J Theor Biol. 2014 Jan 7;340:111-8. doi: 10.1016/j.jtbi.2013.09.009. Epub 2013 Sep 17.

PMID:
24055401
[PubMed - indexed for MEDLINE]
2.

Mitochondrial mutations and aging: random drift is insufficient to explain the accumulation of mitochondrial deletion mutants in short-lived animals.

Kowald A, Kirkwood TB.

Aging Cell. 2013 Aug;12(4):728-31. doi: 10.1111/acel.12098. Epub 2013 Jun 7.

PMID:
23742009
[PubMed - indexed for MEDLINE]
Free Article
3.

Transcription could be the key to the selection advantage of mitochondrial deletion mutants in aging.

Kowald A, Kirkwood TB.

Proc Natl Acad Sci U S A. 2014 Feb 25;111(8):2972-7. doi: 10.1073/pnas.1314970111. Epub 2014 Feb 3.

PMID:
24569805
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Germline mitochondrial DNA mutations aggravate ageing and can impair brain development.

Ross JM, Stewart JB, Hagström E, Brené S, Mourier A, Coppotelli G, Freyer C, Lagouge M, Hoffer BJ, Olson L, Larsson NG.

Nature. 2013 Sep 19;501(7467):412-5. doi: 10.1038/nature12474. Epub 2013 Aug 21.

PMID:
23965628
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Mitochondrial DNA alterations as ageing-associated molecular events.

Wei YH.

Mutat Res. 1992 Sep;275(3-6):145-55. Review.

PMID:
1383757
[PubMed - indexed for MEDLINE]
6.

Is selection required for the accumulation of somatic mitochondrial DNA mutations in post-mitotic cells?

Durham SE, Samuels DC, Chinnery PF.

Neuromuscul Disord. 2006 Jun;16(6):381-6. Epub 2006 May 8.

PMID:
16684599
[PubMed - indexed for MEDLINE]
7.

On the relevance of mitochondrial fusions for the accumulation of mitochondrial deletion mutants: a modelling study.

Kowald A, Jendrach M, Pohl S, Bereiter-Hahn J, Hammerstein P.

Aging Cell. 2005 Oct;4(5):273-83.

PMID:
16164426
[PubMed - indexed for MEDLINE]
8.

Contribution of common deletion to total deletion burden in mitochondrial DNA from inner ear of d-galactose-induced aging rats.

Zhong Y, Hu YJ, Yang Y, Peng W, Sun Y, Chen B, Huang X, Kong WJ.

Mutat Res. 2011 Jul 1;712(1-2):11-9. doi: 10.1016/j.mrfmmm.2011.03.013. Epub 2011 Apr 5.

PMID:
21473872
[PubMed - indexed for MEDLINE]
9.

Mutations of mitochondrial DNA - cause or consequence of the ageing process?

Meissner C.

Z Gerontol Geriatr. 2007 Oct;40(5):325-33. Review.

PMID:
17943235
[PubMed - indexed for MEDLINE]
10.

The mitochondrial theory of aging: do damaged mitochondria accumulate by delayed degradation?

Kowald A.

Exp Gerontol. 1999 Aug;34(5):605-12. Review.

PMID:
10530786
[PubMed - indexed for MEDLINE]
11.

Mitochondria and ageing.

Müller-Höcker J.

Brain Pathol. 1992 Apr;2(2):149-58. Review.

PMID:
1341956
[PubMed - indexed for MEDLINE]
12.

In vivo interaction between mitochondria carrying mtDNAs from different mouse species.

Sato A, Nakada K, Shitara H, Yonekawa H, Hayashi J.

Genetics. 2004 Aug;167(4):1855-61.

PMID:
15342523
[PubMed - indexed for MEDLINE]
Free PMC Article
13.
14.

Mitochondrial DNA mutation and the ageing process: bioenergy and pharmacological intervention.

Linnane AW, Zhang C, Baumer A, Nagley P.

Mutat Res. 1992 Sep;275(3-6):195-208. Review.

PMID:
1383761
[PubMed - indexed for MEDLINE]
15.

Mathematical modeling of the role of mitochondrial fusion and fission in mitochondrial DNA maintenance.

Tam ZY, Gruber J, Halliwell B, Gunawan R.

PLoS One. 2013 Oct 11;8(10):e76230. doi: 10.1371/journal.pone.0076230. eCollection 2013.

PMID:
24146842
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Mitochondrial DNA mutations in disease and ageing.

Cottrell DA, Blakely EL, Johnson MA, Borthwick GM, Ince PI, Turnbull DM.

Novartis Found Symp. 2001;235:234-43; discussion 243-6. Review.

PMID:
11280028
[PubMed - indexed for MEDLINE]
17.

The mitochondrial free radical theory of aging: a critical view.

Sanz A, Stefanatos RK.

Curr Aging Sci. 2008 Mar;1(1):10-21.

PMID:
20021368
[PubMed - indexed for MEDLINE]
18.

DNA deletions and clonal mutations drive premature aging in mitochondrial mutator mice.

Vermulst M, Wanagat J, Kujoth GC, Bielas JH, Rabinovitch PS, Prolla TA, Loeb LA.

Nat Genet. 2008 Apr;40(4):392-4. doi: 10.1038/ng.95. Epub 2008 Mar 2.

PMID:
18311139
[PubMed - indexed for MEDLINE]
19.

Estimation of the mtDNA mutation rate in aging mice by proteome analysis and mathematical modeling.

Mao L, Zabel C, Wacker MA, Nebrich G, Sagi D, Schrade P, Bachmann S, Kowald A, Klose J.

Exp Gerontol. 2006 Jan;41(1):11-24. Epub 2005 Nov 22.

PMID:
16307857
[PubMed - indexed for MEDLINE]
20.

Mitochondrial DNA deletion mutations: a causal role in sarcopenia.

McKenzie D, Bua E, McKiernan S, Cao Z, Aiken JM; Jonathan Wanagat.

Eur J Biochem. 2002 Apr;269(8):2010-5. Review.

PMID:
11985577
[PubMed - indexed for MEDLINE]
Free Article

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